NO983464L - Buffer systems for stabilizing pharmaceutical preparations - Google Patents

Buffer systems for stabilizing pharmaceutical preparations

Info

Publication number
NO983464L
NO983464L NO983464A NO983464A NO983464L NO 983464 L NO983464 L NO 983464L NO 983464 A NO983464 A NO 983464A NO 983464 A NO983464 A NO 983464A NO 983464 L NO983464 L NO 983464L
Authority
NO
Norway
Prior art keywords
buffer systems
pharmaceutical preparations
stabilizing pharmaceutical
stabilizing
preparation
Prior art date
Application number
NO983464A
Other languages
Norwegian (no)
Other versions
NO983464D0 (en
Inventor
Andreas Sachse
Ralf-Siegbert Hauck
Ssling Georg R
Ritz Detlef G
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO983464D0 publication Critical patent/NO983464D0/en
Publication of NO983464L publication Critical patent/NO983464L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Den foreliggende patentsøknad vedrører nye buffersystemer, bestående av et fysiologisk akseptabelt amin og en karboksylsyre, for fremstilling av farmasøytiske midler.The present patent application relates to novel buffer systems, consisting of a physiologically acceptable amine and a carboxylic acid, for the preparation of pharmaceutical agents.

NO983464A 1996-01-29 1998-07-28 Buffer systems for stabilizing pharmaceutical preparations NO983464L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19604230 1996-01-29
PCT/DE1996/002488 WO1997028104A2 (en) 1996-01-29 1996-12-20 Buffer systems for use in stabilizing pharmaceutical preparations

Publications (2)

Publication Number Publication Date
NO983464D0 NO983464D0 (en) 1998-07-28
NO983464L true NO983464L (en) 1998-07-28

Family

ID=7784639

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983464A NO983464L (en) 1996-01-29 1998-07-28 Buffer systems for stabilizing pharmaceutical preparations

Country Status (7)

Country Link
EP (1) EP0877628A2 (en)
JP (1) JP2000504334A (en)
AU (1) AU1870497A (en)
CA (1) CA2244213A1 (en)
DE (1) DE19648650C2 (en)
NO (1) NO983464L (en)
WO (1) WO1997028104A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250153B2 (en) * 2002-12-12 2007-07-31 Biophysica Research, Inc. Contrast media formulations having improved biological tolerance
JP2005170928A (en) * 2003-10-21 2005-06-30 Konica Minolta Medical & Graphic Inc Lyposome-containing x ray-imaging agent and method for producing the same
JP2005170923A (en) * 2003-10-21 2005-06-30 Konica Minolta Medical & Graphic Inc Lyposome-containing x ray-imaging agent and method for producing the same
JP2005220034A (en) * 2004-02-03 2005-08-18 Konica Minolta Medical & Graphic Inc Method for producing contrast medium for roentgenologic examination
JP4654590B2 (en) * 2004-03-31 2011-03-23 コニカミノルタエムジー株式会社 Contrast composition for X-ray CT and method for producing the same
JPWO2006009022A1 (en) * 2004-07-21 2008-05-01 コニカミノルタエムジー株式会社 Liposome-containing X-ray contrast medium and method for producing the same
RU2012138280A (en) 2010-03-23 2014-04-27 ДжиИ Хелткер АС OBTAINING A STABILIZED DIAGNOSTIC COMPOSITION FOR X-RAY STUDY
SG11201501010QA (en) 2012-08-10 2015-04-29 Taiho Pharmaceutical Co Ltd Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
PL3021859T3 (en) 2013-10-25 2018-06-29 Psioxus Therapeutics Limited Oncolytic adenoviruses armed with heterologous genes
CA3006859A1 (en) 2015-12-17 2017-06-22 Psioxus Therapeutics Limited Group b adenovirus encoding an anti-tcr-complex antibody or fragment
CN109862912B (en) 2016-08-29 2024-08-02 阿卡米斯生物公司 Adenovirus carrying dual specificity T cell adapter
JP6867639B2 (en) * 2016-10-11 2021-05-12 学校法人 聖マリアンナ医科大学 Combined nonionic iodine contrast agent
GB201801614D0 (en) 2018-01-31 2018-03-14 Psioxus Therapeutics Ltd Formulation
EP4011369A1 (en) 2020-12-14 2022-06-15 G.L. Pharma GmbH Aqueous pharmaceutical composition comprising tapentadol tartrate
JP7372429B1 (en) 2022-10-31 2023-10-31 キユーピー株式会社 Emulsion and its manufacturing method
JP7353453B1 (en) 2022-10-31 2023-09-29 キユーピー株式会社 Emulsion and its manufacturing method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4278654A (en) * 1978-07-04 1981-07-14 Nyegaard & Co. A/S Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
DE4121568C2 (en) * 1991-04-22 1997-07-03 Schering Ag Method and device for producing a contrast medium from a concentrate
IT1256248B (en) * 1992-12-24 1995-11-29 Bracco Spa WATER INJECTABLE FORMULATIONS FOR RADIODIAGNOSTICS INCLUDING MIXTURES OF IODURATED AROMATIC COMPOUNDS USEFUL AS X-RAY MATTING AGENTS

Also Published As

Publication number Publication date
DE19648650A1 (en) 1997-08-07
EP0877628A2 (en) 1998-11-18
CA2244213A1 (en) 1997-08-07
NO983464D0 (en) 1998-07-28
DE19648650C2 (en) 1998-07-02
WO1997028104A2 (en) 1997-08-07
JP2000504334A (en) 2000-04-11
AU1870497A (en) 1997-08-22
WO1997028104A3 (en) 1997-09-12
WO1997028104A8 (en) 1997-12-18

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application