NO982709L - Process for Preparation of S- (R, R *) | -3-Methyl-2 (3-oxo-3H-benzoic acid) -thiazol-2-yl) pentaenoic acid and S- (R, R *) | , L-2- {2- £ 2- (1-carboxy-2-methylbutylcarbamoyl) phenyldisulfonyl | benzoylamino-3-metylpentaensyre - Google Patents

Process for Preparation of S- (R, R *) | -3-Methyl-2 (3-oxo-3H-benzoic acid) -thiazol-2-yl) pentaenoic acid and S- (R, R *) | , L-2- {2- £ 2- (1-carboxy-2-methylbutylcarbamoyl) phenyldisulfonyl | benzoylamino-3-metylpentaensyre

Info

Publication number
NO982709L
NO982709L NO982709A NO982709A NO982709L NO 982709 L NO982709 L NO 982709L NO 982709 A NO982709 A NO 982709A NO 982709 A NO982709 A NO 982709A NO 982709 L NO982709 L NO 982709L
Authority
NO
Norway
Prior art keywords
phenyldisulfonyl
methylbutylcarbamoyl
benzoylamino
oxo
carboxy
Prior art date
Application number
NO982709A
Other languages
Norwegian (no)
Other versions
NO982709D0 (en
Inventor
Phillip Fiore
Timothy P Puls
Jonathan Walker
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO982709D0 publication Critical patent/NO982709D0/en
Publication of NO982709L publication Critical patent/NO982709L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Foreliggende oppfinnelse tilveiebringer en forbedret syntese av [S-(R*,R*)]-3-metyl-2-(3-okso-3H-benzo[d]isotiazol-2-yl)pentansyreog [S-(R*,R*)],L-2-{2-[2-(1-karboksy-2-metylbutylkarbamoyl)fenyldisulfonyl]- benzoylamino}-3-metylpentansyre.The present invention provides an improved synthesis of [S- (R *, R *)] - 3-methyl-2- (3-oxo-3H-benzo [d] isothiazol-2-yl) pentanoic acid and [S- (R *, R *)], L-2- {2- [2- (1-carboxy-2-methylbutylcarbamoyl) phenyldisulfonyl] benzoylamino} -3-methylpentanoic acid.

NO982709A 1995-12-15 1998-06-12 Process for Preparation of S- (R, R *) | -3-Methyl-2 (3-oxo-3H-benzoic acid) -thiazol-2-yl) pentaenoic acid and S- (R, R *) | , L-2- {2- £ 2- (1-carboxy-2-methylbutylcarbamoyl) phenyldisulfonyl | benzoylamino-3-metylpentaensyre NO982709L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US874595P 1995-12-15 1995-12-15
PCT/US1996/018929 WO1997022598A1 (en) 1995-12-15 1996-11-27 Method of making (s-(r*,r*))-3-methyl-2-(3-oxo-3h-benzo(d)isothiazol-2-yl)pentanoic acid and (s-(r*,r*)), l-2-(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulfonyl)benzoyl-amino)-3-methylpentanoic acid

Publications (2)

Publication Number Publication Date
NO982709D0 NO982709D0 (en) 1998-06-12
NO982709L true NO982709L (en) 1998-06-12

Family

ID=21733413

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982709A NO982709L (en) 1995-12-15 1998-06-12 Process for Preparation of S- (R, R *) | -3-Methyl-2 (3-oxo-3H-benzoic acid) -thiazol-2-yl) pentaenoic acid and S- (R, R *) | , L-2- {2- £ 2- (1-carboxy-2-methylbutylcarbamoyl) phenyldisulfonyl | benzoylamino-3-metylpentaensyre

Country Status (17)

Country Link
EP (1) EP0874835A1 (en)
JP (1) JP2000505067A (en)
KR (1) KR20000064403A (en)
CN (1) CN1208407A (en)
AU (1) AU1083597A (en)
BG (1) BG102470A (en)
BR (1) BR9612020A (en)
CA (1) CA2233553A1 (en)
CZ (1) CZ182498A3 (en)
HU (1) HUP9902043A3 (en)
IL (1) IL123903A0 (en)
NO (1) NO982709L (en)
NZ (1) NZ323803A (en)
PL (1) PL327135A1 (en)
SK (1) SK81798A3 (en)
WO (1) WO1997022598A1 (en)
ZA (1) ZA9610479B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9304903D0 (en) * 1993-03-10 1993-04-28 Zeneca Ltd Compounds,preparation and use
US5734081A (en) * 1994-08-05 1998-03-31 Warner-Lambert Company Arylthio compounds
US5463122A (en) * 1994-08-05 1995-10-31 Warner-Lambert Company Arylthio compounds

Also Published As

Publication number Publication date
NO982709D0 (en) 1998-06-12
JP2000505067A (en) 2000-04-25
IL123903A0 (en) 1998-10-30
HUP9902043A2 (en) 1999-11-29
SK81798A3 (en) 1998-11-04
BG102470A (en) 1999-08-31
KR20000064403A (en) 2000-11-06
HUP9902043A3 (en) 2000-03-28
AU1083597A (en) 1997-07-14
CA2233553A1 (en) 1997-06-26
PL327135A1 (en) 1998-11-23
NZ323803A (en) 1999-02-25
CZ182498A3 (en) 1998-09-16
CN1208407A (en) 1999-02-17
EP0874835A1 (en) 1998-11-04
WO1997022598A1 (en) 1997-06-26
ZA9610479B (en) 1998-06-09
BR9612020A (en) 1999-06-29

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