BG102470A - Method for the preparation of [s-r*, r*)]-3-methyl- 2-(oxo-3h-benzo(d)isothiazol-2-yl)pentane acid and [s-(r*, r*)], l-2--(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulphonyl)ben zoyl-amino-3-methylpentane acid - Google Patents

Method for the preparation of [s-r*, r*)]-3-methyl- 2-(oxo-3h-benzo(d)isothiazol-2-yl)pentane acid and [s-(r*, r*)], l-2--(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulphonyl)ben zoyl-amino-3-methylpentane acid

Info

Publication number
BG102470A
BG102470A BG102470A BG10247098A BG102470A BG 102470 A BG102470 A BG 102470A BG 102470 A BG102470 A BG 102470A BG 10247098 A BG10247098 A BG 10247098A BG 102470 A BG102470 A BG 102470A
Authority
BG
Bulgaria
Prior art keywords
acid
phenyldisulphonyl
methylbutylcarbamoyl
isothiazol
benzo
Prior art date
Application number
BG102470A
Other languages
Bulgarian (bg)
Inventor
Phillip Fiore
Timothy Puls
Jonathan Walker
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of BG102470A publication Critical patent/BG102470A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

The invention relates to the synthesis of the compounds shownin the title above.12 claims
BG102470A 1995-12-15 1998-05-20 Method for the preparation of [s-r*, r*)]-3-methyl- 2-(oxo-3h-benzo(d)isothiazol-2-yl)pentane acid and [s-(r*, r*)], l-2--(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulphonyl)ben zoyl-amino-3-methylpentane acid BG102470A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US874595P 1995-12-15 1995-12-15
PCT/US1996/018929 WO1997022598A1 (en) 1995-12-15 1996-11-27 Method of making (s-(r*,r*))-3-methyl-2-(3-oxo-3h-benzo(d)isothiazol-2-yl)pentanoic acid and (s-(r*,r*)), l-2-(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulfonyl)benzoyl-amino)-3-methylpentanoic acid

Publications (1)

Publication Number Publication Date
BG102470A true BG102470A (en) 1999-08-31

Family

ID=21733413

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102470A BG102470A (en) 1995-12-15 1998-05-20 Method for the preparation of [s-r*, r*)]-3-methyl- 2-(oxo-3h-benzo(d)isothiazol-2-yl)pentane acid and [s-(r*, r*)], l-2--(2-(2-(1-carboxy-2-methylbutylcarbamoyl)phenyldisulphonyl)ben zoyl-amino-3-methylpentane acid

Country Status (17)

Country Link
EP (1) EP0874835A1 (en)
JP (1) JP2000505067A (en)
KR (1) KR20000064403A (en)
CN (1) CN1208407A (en)
AU (1) AU1083597A (en)
BG (1) BG102470A (en)
BR (1) BR9612020A (en)
CA (1) CA2233553A1 (en)
CZ (1) CZ182498A3 (en)
HU (1) HUP9902043A3 (en)
IL (1) IL123903A0 (en)
NO (1) NO982709L (en)
NZ (1) NZ323803A (en)
PL (1) PL327135A1 (en)
SK (1) SK81798A3 (en)
WO (1) WO1997022598A1 (en)
ZA (1) ZA9610479B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9304903D0 (en) * 1993-03-10 1993-04-28 Zeneca Ltd Compounds,preparation and use
US5734081A (en) * 1994-08-05 1998-03-31 Warner-Lambert Company Arylthio compounds
US5463122A (en) * 1994-08-05 1995-10-31 Warner-Lambert Company Arylthio compounds

Also Published As

Publication number Publication date
NO982709D0 (en) 1998-06-12
JP2000505067A (en) 2000-04-25
ZA9610479B (en) 1998-06-09
SK81798A3 (en) 1998-11-04
AU1083597A (en) 1997-07-14
EP0874835A1 (en) 1998-11-04
CN1208407A (en) 1999-02-17
WO1997022598A1 (en) 1997-06-26
HUP9902043A3 (en) 2000-03-28
IL123903A0 (en) 1998-10-30
CZ182498A3 (en) 1998-09-16
NO982709L (en) 1998-06-12
NZ323803A (en) 1999-02-25
PL327135A1 (en) 1998-11-23
KR20000064403A (en) 2000-11-06
CA2233553A1 (en) 1997-06-26
HUP9902043A2 (en) 1999-11-29
BR9612020A (en) 1999-06-29

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