NO975660L - Use of benzimidazoles for the manufacture of a medicament for the treatment of leukemia - Google Patents

Use of benzimidazoles for the manufacture of a medicament for the treatment of leukemia

Info

Publication number
NO975660L
NO975660L NO975660A NO975660A NO975660L NO 975660 L NO975660 L NO 975660L NO 975660 A NO975660 A NO 975660A NO 975660 A NO975660 A NO 975660A NO 975660 L NO975660 L NO 975660L
Authority
NO
Norway
Prior art keywords
carbon atoms
less
hydrogen
leukemia
benzimidazoles
Prior art date
Application number
NO975660A
Other languages
Norwegian (no)
Other versions
NO975660D0 (en
Inventor
James Berger Camden
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO975660D0 publication Critical patent/NO975660D0/en
Publication of NO975660L publication Critical patent/NO975660L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Et farmasøytisk preparat for behandling av leukemi i pattedyr. Det spesielle fungicidet som anvendes er et benzimidazolderivat med formel (I) hvor X er hydrogen, halogen, alkyl med mindre enn 7 karbonatomer eller alkoksy med mindre enn 7 karbonatomer, n er et positivt helt tall som er mindre enn 4, Y er hydrogen, klor, nitro, metyl eller etyl, og R er hydrogen eller en alkylgruppe med fra l til 8 karbonatomer og R2 er 4-tiazolyl eller NHCOORj hvor Rj er alifatisk hydrokarbon med mindre enn 7 karbonatomer, eller de farmasøytisk tålbare organiske eller uorganiske syreaddisjonssalter derav.A pharmaceutical preparation for treating leukemia in mammals. The particular fungicide used is a benzimidazole derivative of formula (I) wherein X is hydrogen, halogen, alkyl of less than 7 carbon atoms or alkoxy of less than 7 carbon atoms, n is a positive integer less than 4, Y is hydrogen, chlorine, nitro, methyl or ethyl, and R is hydrogen or an alkyl group having from 1 to 8 carbon atoms and R 2 is 4-thiazolyl or NHCOOR 3 wherein R 1 is aliphatic hydrocarbon having less than 7 carbon atoms, or the pharmaceutically acceptable organic or inorganic acid addition salts thereof.

NO975660A 1995-06-07 1997-12-05 Use of benzimidazoles for the manufacture of a medicament for the treatment of leukemia NO975660L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47381795A 1995-06-07 1995-06-07
PCT/US1996/007445 WO1996040122A1 (en) 1995-06-07 1996-05-22 Use of benzimidazoles for the manufacture of a medicament for the treatment of leukemia

Publications (2)

Publication Number Publication Date
NO975660D0 NO975660D0 (en) 1997-12-05
NO975660L true NO975660L (en) 1998-02-09

Family

ID=23881113

Family Applications (1)

Application Number Title Priority Date Filing Date
NO975660A NO975660L (en) 1995-06-07 1997-12-05 Use of benzimidazoles for the manufacture of a medicament for the treatment of leukemia

Country Status (17)

Country Link
EP (1) EP0831816A1 (en)
JP (1) JPH11506732A (en)
KR (1) KR19990022617A (en)
CN (1) CN1186433A (en)
AR (1) AR003137A1 (en)
AU (1) AU717382B2 (en)
BR (1) BR9608730A (en)
CA (1) CA2223435A1 (en)
CZ (1) CZ391197A3 (en)
HU (1) HUP9802634A3 (en)
IL (1) IL118424A0 (en)
NO (1) NO975660L (en)
PL (1) PL324026A1 (en)
SK (1) SK168697A3 (en)
TR (1) TR199701536T1 (en)
WO (1) WO1996040122A1 (en)
ZA (1) ZA964373B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6177460B1 (en) 1995-04-12 2001-01-23 The Procter & Gamble Company Method of treatment for cancer or viral infections
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US6686391B2 (en) 1995-08-04 2004-02-03 University Of Arizona Foundation N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6608096B1 (en) 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6462062B1 (en) 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
EP2251010A1 (en) 2009-05-08 2010-11-17 Sygnis Bioscience GmbH & Co. KG Use of thiabendazole and derivatives thereof for the therapy of neurological conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL134354C (en) * 1963-05-23
FR2155888A1 (en) * 1971-10-13 1973-05-25 Agot Aime Solid anthelmintic composn - for more economical treatment of ruminants

Also Published As

Publication number Publication date
BR9608730A (en) 1999-06-29
CA2223435A1 (en) 1996-12-19
AU5802096A (en) 1996-12-30
NO975660D0 (en) 1997-12-05
KR19990022617A (en) 1999-03-25
CN1186433A (en) 1998-07-01
SK168697A3 (en) 1998-12-02
TR199701536T1 (en) 1998-02-21
ZA964373B (en) 1996-09-02
JPH11506732A (en) 1999-06-15
IL118424A0 (en) 1996-09-12
HUP9802634A2 (en) 1999-03-29
PL324026A1 (en) 1998-05-11
CZ391197A3 (en) 1998-05-13
AR003137A1 (en) 1998-07-08
WO1996040122A1 (en) 1996-12-19
AU717382B2 (en) 2000-03-23
EP0831816A1 (en) 1998-04-01
HUP9802634A3 (en) 1999-05-28

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application