NO964472D0 - Halo methylamides as IL-1 prosthesis inhibitors - Google Patents

Halo methylamides as IL-1 prosthesis inhibitors

Info

Publication number
NO964472D0
NO964472D0 NO964472A NO964472A NO964472D0 NO 964472 D0 NO964472 D0 NO 964472D0 NO 964472 A NO964472 A NO 964472A NO 964472 A NO964472 A NO 964472A NO 964472 D0 NO964472 D0 NO 964472D0
Authority
NO
Norway
Prior art keywords
methylamides
prosthesis
halo
inhibitors
prosthesis inhibitors
Prior art date
Application number
NO964472A
Other languages
Norwegian (no)
Other versions
NO964472L (en
Inventor
Roland E Dolle
James M Rinker
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of NO964472D0 publication Critical patent/NO964472D0/en
Publication of NO964472L publication Critical patent/NO964472L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/25—Aminoacetonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO964472A 1994-04-29 1996-10-21 Halo methylamides as IL-1 prosthesis inhibitors NO964472L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23642594A 1994-04-29 1994-04-29
PCT/US1995/005347 WO1995029672A1 (en) 1994-04-29 1995-04-28 HALOMETHYL AMIDES AS IL-1β PROTEASE INHIBITORS

Publications (2)

Publication Number Publication Date
NO964472D0 true NO964472D0 (en) 1996-10-21
NO964472L NO964472L (en) 1996-10-21

Family

ID=22889450

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964472A NO964472L (en) 1994-04-29 1996-10-21 Halo methylamides as IL-1 prosthesis inhibitors

Country Status (9)

Country Link
EP (1) EP0758891A4 (en)
JP (1) JPH09512556A (en)
CN (1) CN1147201A (en)
AU (1) AU705321B2 (en)
CA (1) CA2189036A1 (en)
FI (1) FI964342A0 (en)
MX (1) MX9605196A (en)
NO (1) NO964472L (en)
WO (1) WO1995029672A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008217A (en) * 1995-12-20 1999-12-28 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β converting enzyme
US5874424A (en) * 1995-12-20 1999-02-23 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β converting enzyme
US6204261B1 (en) 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US6420522B1 (en) 1995-06-05 2002-07-16 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β converting enzyme
CA2215211A1 (en) * 1995-03-31 1996-10-03 Takeda Chemical Industries, Ltd. Cysteine protease inhibitor
US5843904A (en) * 1995-12-20 1998-12-01 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1βconverting enzyme
DE69925581T2 (en) 1998-03-09 2006-04-27 Vertex Pharmaceuticals Inc., Cambridge 1,2-DIAZEPANDERIVATE AS INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME
EP2261233A3 (en) 1998-03-19 2011-04-20 Vertex Pharmaceuticals Incorporated Inhibitors of caspases
GB9922830D0 (en) 1999-09-27 1999-11-24 Novartis Ag Processes
AU779855B2 (en) * 2000-01-06 2005-02-17 Axys Pharmaceuticals, Inc. Novel compounds and compositions as protease inhibitors
PE20011350A1 (en) 2000-05-19 2002-01-15 Vertex Pharma PROPHARMAC OF AN INHIBITOR OF INTERLEUKIN-1ß CONVERTER ENZYME (ICE)
CA2464846C (en) 2002-08-30 2010-04-06 Japan Tobacco Inc. Dibenzylamine compounds and pharmaceutical use thereof
CN100441186C (en) * 2003-12-03 2008-12-10 和记黄埔医药企业有限公司 Medical use of artificial lywrine
CA2567080A1 (en) 2004-05-27 2005-12-15 Vertex Pharmaceuticals Incorporated Ice inhibitors for the treatment of autoinflammatory diseases
US9956260B1 (en) 2011-07-22 2018-05-01 The J. David Gladstone Institutes Treatment of HIV-1 infection and AIDS

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1806291A1 (en) * 1968-10-31 1970-05-14 Badische Anilin Und & Soda Fab fungicide
US4195096A (en) * 1977-01-12 1980-03-25 Gaf Corporation Carboxylic amides as fungicides to eumycotina in phanerogamia plant life
DE2946910A1 (en) * 1979-11-21 1981-07-02 Hoechst Ag, 6230 Frankfurt FUNGICIDAL SULFONYL, BZW. SULFINYL ACETANILIDE
DE3122738A1 (en) * 1980-06-12 1982-03-18 CIBA-GEIGY AG, 4002 Basel "USE OF IODOACETAMIDE FOR CONTROLLING PAD ORGANISMS AND AGENT FOR CONTROLLING"
US4377587A (en) * 1980-07-25 1983-03-22 Ciba-Geigy Corporation Arylamine derivatives and use thereof as microbicides
JPS5798202A (en) * 1980-12-09 1982-06-18 Kumiai Chem Ind Co Ltd Herbicide
DE3276110D1 (en) * 1981-03-04 1987-05-27 Ici Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them
DE3339351A1 (en) * 1983-10-29 1985-05-09 Bayer Ag, 5090 Leverkusen IODACETAMIDE
US4800211A (en) * 1986-08-18 1989-01-24 Merck & Co., Inc. 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
US4874864A (en) * 1988-05-24 1989-10-17 Pfizer Inc. Benzamide protease inhibitors
US5258407A (en) * 1991-12-31 1993-11-02 Sterling Winthrop Inc. 3,4-disubstituted phenols-immunomodulating agents

Also Published As

Publication number Publication date
MX9605196A (en) 1997-12-31
JPH09512556A (en) 1997-12-16
WO1995029672A1 (en) 1995-11-09
CN1147201A (en) 1997-04-09
EP0758891A4 (en) 1997-12-03
AU2463495A (en) 1995-11-29
FI964342A (en) 1996-10-28
NO964472L (en) 1996-10-21
FI964342A0 (en) 1996-10-28
AU705321B2 (en) 1999-05-20
EP0758891A1 (en) 1997-02-26
CA2189036A1 (en) 1995-11-09

Similar Documents

Publication Publication Date Title
FI963597A (en) Isoprenyylitransferaasi inhibitors
NO972930D0 (en) Fibronectin-adhesion inhibitors
DE59507573D1 (en) Implant
NO980467L (en) 4-mercaptopyrrolidine derivatives as farnesyl transerase inhibitors
NO20006716D0 (en) protease inhibitors
NO992725L (en) 6-Phenylpyridyl-2-amine derivatives useful as NOS inhibitors
DE69515163D1 (en) Photoresist compositions
NO964472D0 (en) Halo methylamides as IL-1 prosthesis inhibitors
DE69503738T2 (en) Photopolymerizable composition
DE59402543D1 (en) Resilient stem
DE69526475D1 (en) 5-alpha-reductase inhibitors
FI971447A0 (en) Valve for hand basin
DE59506738D1 (en) STEM DEVICE
DE69530085D1 (en) SYNERGISTIC REMOVER
FI951188A0 (en) Valve
KR960016621U (en) spanner
CY2007006I2 (en) ALIPOPROTEIN-B INHIBITORS
KR970064049U (en) Transformer valve
FI944788A0 (en) Skidstav som foeljer roerelse
FI1600U1 (en) Bojhakes regel
KR960004244U (en) wrench
FI945342A0 (en) Rule
SE9402923D0 (en) STOP vALVE
BR7400608U (en) Hydropole valve
KR960002320U (en) valve

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application