NO963762L - New use of quinoline-3-carboxamide compounds - Google Patents
New use of quinoline-3-carboxamide compoundsInfo
- Publication number
- NO963762L NO963762L NO963762A NO963762A NO963762L NO 963762 L NO963762 L NO 963762L NO 963762 A NO963762 A NO 963762A NO 963762 A NO963762 A NO 963762A NO 963762 L NO963762 L NO 963762L
- Authority
- NO
- Norway
- Prior art keywords
- quinoline
- atoms
- psoriasis
- carboxamide
- methyl
- Prior art date
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Anvendelse av en anti-psoriatisk kinolin-3-karboksamid- forbindelse omfattende strukturen (I) ovenfor, valg- fritt med substituenter for de viste hydrogenatomer (H ), eller et farmasøytisk akseptabelt salt av for- bindelsen, hvor (a)-----betyr at det er to konjugerte dobbeltbindinger mellom atomene, hvilke bindinger representeres med den stiplede linje; (b) X, og X2 hver uavhengig utvelges fra et oksygenatom og en NH9-gruppe, hvor X, og X2 er bundet til ringen med en enkeltbinding når de er forbundet med H7 eller H8, og med en dobbelt- binding når de ikke er forbundet med H7 eller H8; (c) H " hver betyr et hydrogenatom, med det forbehold at H9 kun forekommer når minst en av x, og XE betyr en NH9- gruppe; (d) H7 og H8 hver betyr et hydrogenatom som er forbundet med forskjellige atomer utvalgt fra X,, X2 og nitrogenatomet (N) i kinolinringen, ved fremstilling av en sammensetning for behandling av psoriasis eller til- stander forbundet med psoriasis. Det beskrives også fremgangsmåter ved behandling av psoriasis eller til- stander forbundet med psoriasis, ved hvilke fremgangs- måter ovennevnte forbindelser administreres til et levende vesen. Spesielt foretrukne forbindelser er N- fenyl-N-metyl-1,2-dihydro-4-hydroksy-l-metyl-2-okso- kinolin-3-karboksamid eller et salt derav.Use of an anti-psoriatic quinoline-3-carboxamide compound comprising structure (I) above, optionally with substituents for the hydrogen atoms (H) shown, or a pharmaceutically acceptable salt of the compound, wherein (a) --- - means that there are two conjugated double bonds between the atoms, which bonds are represented by the dotted line; (b) X and X2 are each independently selected from an oxygen atom and an NH9 group, wherein X and X2 are bonded to the ring by a single bond when linked to H7 or H8, and by a double bond when not associated with H7 or H8; (c) H "each means a hydrogen atom, with the proviso that H9 occurs only when at least one of x, and XE represents an NH9 group; (d) H7 and H8 each means a hydrogen atom associated with different atoms selected from X "X2 and the nitrogen atom (N) in the quinoline ring, in the preparation of a composition for the treatment of psoriasis or conditions associated with psoriasis. Particularly preferred compounds are N-phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide or a salt thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9400810A SE9400810D0 (en) | 1994-03-10 | 1994-03-10 | New use of quinoline-3-carboxamide compounds |
| PCT/SE1995/000245 WO1995024196A1 (en) | 1994-03-10 | 1995-03-08 | New use of quinoline-3-carboxamide compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO963762L true NO963762L (en) | 1996-09-09 |
| NO963762D0 NO963762D0 (en) | 1996-09-09 |
Family
ID=26661988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO963762A NO963762D0 (en) | 1994-03-10 | 1996-09-09 | New use of quinoline-3-carboxamide compounds |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO963762D0 (en) |
-
1996
- 1996-09-09 NO NO963762A patent/NO963762D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO963762D0 (en) | 1996-09-09 |
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