NO954403L - Antibodies to P-selectin and their use - Google Patents

Antibodies to P-selectin and their use

Info

Publication number
NO954403L
NO954403L NO954403A NO954403A NO954403L NO 954403 L NO954403 L NO 954403L NO 954403 A NO954403 A NO 954403A NO 954403 A NO954403 A NO 954403A NO 954403 L NO954403 L NO 954403L
Authority
NO
Norway
Prior art keywords
antibodies
selectin
activated
murine
vivo
Prior art date
Application number
NO954403A
Other languages
Norwegian (no)
Other versions
NO954403D0 (en
Inventor
Robert W Chesnut
Margaret J Polley
James C Paulson
S Tarran Jones
Jose W Saldanha
Mary M Bendig
Michael Kriegler
Carl Perez
Robert Bayer
Michael Nunn
Original Assignee
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1993/004274 external-priority patent/WO1993021956A1/en
Priority claimed from US08/202,047 external-priority patent/US5800815A/en
Priority claimed from PCT/US1994/004935 external-priority patent/WO1994025067A1/en
Application filed by Cytel Corp filed Critical Cytel Corp
Publication of NO954403D0 publication Critical patent/NO954403D0/en
Publication of NO954403L publication Critical patent/NO954403L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Foreliggende oppfinnelse vedrører preparater og fremgangsmåter for be- handling av inflammasjon og andre pato- logiske tilstander under anvendelse av nye blokkerende P-selektinantistoffer som inhiberer adhesjon av leukocytter til aktiverte blodplater og/eller til aktivert vaskulært endotel in vivo. Det er tilveiebrakt både murine og humani- serte antistoffer.The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit leukocyte adhesion to activated platelets and / or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.

NO954403A 1993-05-04 1995-11-03 Antibodies to P-selectin and their use NO954403L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US1993/004274 WO1993021956A1 (en) 1992-05-05 1993-05-04 Antibodies to p-selectin and their uses
US5729293A 1993-05-05 1993-05-05
US08/202,047 US5800815A (en) 1903-05-05 1994-02-25 Antibodies to P-selectin and their uses
PCT/US1994/004935 WO1994025067A1 (en) 1993-05-04 1994-05-04 Antibodies to p-selectin and their uses

Publications (2)

Publication Number Publication Date
NO954403D0 NO954403D0 (en) 1995-11-03
NO954403L true NO954403L (en) 1996-01-03

Family

ID=26736298

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954403A NO954403L (en) 1993-05-04 1995-11-03 Antibodies to P-selectin and their use

Country Status (8)

Country Link
CN (1) CN1124928A (en)
CA (1) CA2162149C (en)
CZ (1) CZ287295A3 (en)
HU (1) HUT75894A (en)
NO (1) NO954403L (en)
NZ (1) NZ266934A (en)
PL (1) PL311666A1 (en)
SK (1) SK137795A3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28886A1 (en) * 2004-05-10 2005-12-30 Boehringer Ingelheim Int ANTIBODIES CONSISTING IN POLYPEPTIDES AND DERIVATIVES UNDERSTANDING THREE SEQUENCES CONCERNING THE FOLLOWING NUMBERS OF SEQ. ID: 1-3 AND 4-6; 7-9 AND 10-12 AND 13-15 OR 16-18
EP2654781B1 (en) * 2010-12-21 2018-01-24 Selexys Pharmaceuticals Corporation Anti-p-selectin antibodies and methods of their use and identification
CN113952468B (en) * 2021-09-26 2023-07-07 中国人民解放军空军军医大学 Cyclosporin A nano-drug for treating myocardial ischemia reperfusion injury

Also Published As

Publication number Publication date
PL311666A1 (en) 1996-03-04
NZ266934A (en) 1997-07-27
SK137795A3 (en) 1996-11-06
NO954403D0 (en) 1995-11-03
CA2162149C (en) 2007-07-10
CA2162149A1 (en) 1994-11-10
HU9503156D0 (en) 1996-01-29
HUT75894A (en) 1997-05-28
CN1124928A (en) 1996-06-19
CZ287295A3 (en) 1996-05-15

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