NO952608L - Derivatized calcitonins - Google Patents

Derivatized calcitonins

Info

Publication number
NO952608L
NO952608L NO952608A NO952608A NO952608L NO 952608 L NO952608 L NO 952608L NO 952608 A NO952608 A NO 952608A NO 952608 A NO952608 A NO 952608A NO 952608 L NO952608 L NO 952608L
Authority
NO
Norway
Prior art keywords
derivatized
molecules
calcitonins
calcitonin
derivatized calcitonins
Prior art date
Application number
NO952608A
Other languages
Norwegian (no)
Other versions
NO952608D0 (en
Inventor
Virender M Labroo
Tomikazu Sasaki
Original Assignee
Zymogenetics Inc
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc, Univ Washington filed Critical Zymogenetics Inc
Publication of NO952608D0 publication Critical patent/NO952608D0/en
Publication of NO952608L publication Critical patent/NO952608L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57527—Calcitonin gene related peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Det er beskrevet derivatiserte kalsitoninmolekyler, farmasøytiske preparater som omfatter derivatiserte kalsitoniner, og fremgangsmåter for reduksjon av serumkalsium hos en pasient under anvendelse av de deri- vatiserte kalsitoniner. Molekylene er kjennetegnet ved en derivatisert amino- ende dannet ved å kombinere et kalsi- tonin med en syklisk, polysyklisk eller heterosyklisk rest. Multimere former av molekylene er også beskrevet.Derivative calcitonin molecules are disclosed, pharmaceutical compositions comprising derivatized calcitonins, and methods for reducing serum calcium in a patient using the derivatized calcitonins. The molecules are characterized by a derivatized amino terminus formed by combining a calcitonin with a cyclic, polycyclic or heterocyclic residue. Multimeric forms of the molecules are also described.

NO952608A 1992-12-31 1995-06-29 Derivatized calcitonins NO952608L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99974992A 1992-12-31 1992-12-31
PCT/US1993/012692 WO1994015962A2 (en) 1992-12-31 1993-12-30 Derivatized calcitonins

Publications (2)

Publication Number Publication Date
NO952608D0 NO952608D0 (en) 1995-06-29
NO952608L true NO952608L (en) 1995-08-30

Family

ID=25546645

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952608A NO952608L (en) 1992-12-31 1995-06-29 Derivatized calcitonins

Country Status (9)

Country Link
EP (1) EP0677062A1 (en)
JP (1) JPH08505393A (en)
KR (1) KR100310280B1 (en)
AU (1) AU673237B2 (en)
CA (1) CA2153071C (en)
FI (1) FI953255A0 (en)
NO (1) NO952608L (en)
NZ (1) NZ261052A (en)
WO (1) WO1994015962A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956260A (en) * 1967-11-09 1976-05-11 Ciba-Geigy Corporation Hypocalcaemic peptides and processes for their manufacture
DE1806135A1 (en) * 1967-11-09 1969-07-17 Ciba Geigy Novel hypocalcaemic peptides and methods of making them
CH523868A (en) * 1969-10-22 1972-06-15 Ciba Geigy Ag Process for the preparation of new dotriacontapeptide amides and their derivatives
NL8602950A (en) * 1985-12-04 1987-07-01 Sandoz Ag CALCITONIN DERIVATIVES AND METHODS FOR PREPARING THESE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
EP0297159A1 (en) * 1987-07-01 1989-01-04 Armour Pharmaceutical Company [N-Acyl, 1,7-Di-Aline] calcitonins, method for their preparation, pharmaceutical compositions and use
EP0298474B1 (en) * 1987-07-08 1992-11-19 Mitsubishi Petrochemical Co., Ltd. Novel calcitonin derivative and salt thereof

Also Published As

Publication number Publication date
CA2153071A1 (en) 1994-07-21
JPH08505393A (en) 1996-06-11
KR100310280B1 (en) 2002-02-28
KR960700273A (en) 1996-01-19
CA2153071C (en) 2000-05-30
AU673237B2 (en) 1996-10-31
AU5962994A (en) 1994-08-15
WO1994015962A3 (en) 1994-09-29
FI953255A (en) 1995-06-30
NO952608D0 (en) 1995-06-29
NZ261052A (en) 1997-10-24
FI953255A0 (en) 1995-06-30
WO1994015962A2 (en) 1994-07-21
EP0677062A1 (en) 1995-10-18

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application