NO952596D0 - Ortho-amino-substituted benzoyl guandines, processes for their preparation, their use as a drug or diagnostic as well as drugs containing them - Google Patents

Ortho-amino-substituted benzoyl guandines, processes for their preparation, their use as a drug or diagnostic as well as drugs containing them

Info

Publication number
NO952596D0
NO952596D0 NO952596A NO952596A NO952596D0 NO 952596 D0 NO952596 D0 NO 952596D0 NO 952596 A NO952596 A NO 952596A NO 952596 A NO952596 A NO 952596A NO 952596 D0 NO952596 D0 NO 952596D0
Authority
NO
Norway
Prior art keywords
guandines
ortho
diagnostic
drug
amino
Prior art date
Application number
NO952596A
Other languages
Norwegian (no)
Other versions
NO952596L (en
Inventor
Jan-Robert Schwark
Hans-Werner Kleemann
Hans-Jochen Lang
Andreas Weichert
Wolfgang Scholz
Udo Albus
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO952596D0 publication Critical patent/NO952596D0/en
Publication of NO952596L publication Critical patent/NO952596L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO952596A 1994-06-29 1995-06-28 Ortho-amino-substituted benzoyl guandines, processes for their preparation, their use as a drug or diagnostic as well as drugs containing them NO952596L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4422685A DE4422685A1 (en) 1994-06-29 1994-06-29 Ortho-amino-substituted benzoylguanidines, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them

Publications (2)

Publication Number Publication Date
NO952596D0 true NO952596D0 (en) 1995-06-28
NO952596L NO952596L (en) 1996-01-02

Family

ID=6521760

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952596A NO952596L (en) 1994-06-29 1995-06-28 Ortho-amino-substituted benzoyl guandines, processes for their preparation, their use as a drug or diagnostic as well as drugs containing them

Country Status (17)

Country Link
EP (1) EP0690048A1 (en)
JP (1) JPH0812643A (en)
CN (1) CN1119183A (en)
AU (1) AU2330095A (en)
CA (1) CA2152878A1 (en)
CZ (1) CZ169295A3 (en)
DE (1) DE4422685A1 (en)
FI (1) FI953173A (en)
HU (1) HUT72413A (en)
IL (1) IL114377A0 (en)
NO (1) NO952596L (en)
NZ (1) NZ272449A (en)
PL (1) PL309386A1 (en)
SI (1) SI9500211A (en)
SK (1) SK84195A3 (en)
TW (1) TW273545B (en)
ZA (1) ZA955342B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430212A1 (en) * 1994-08-28 1996-02-29 Merck Patent Gmbh Ortho-substituted benzoic acid derivatives
EP0765867A1 (en) * 1995-09-27 1997-04-02 Hoechst Aktiengesellschaft Substituted benzoyl guanidines, process for their preparation, their use as antiarrhythmics or diagnostic agent as well as pharmaceuticals containing them
DE19540995A1 (en) * 1995-11-03 1997-05-07 Hoechst Ag Substituted sulfonimidamides, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them
DE19542306A1 (en) * 1995-11-14 1997-05-15 Hoechst Ag Sulfonylamino-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them
PL316439A1 (en) * 1995-11-20 1997-05-26 Hoechst Ag Novel substituted derivatives of benzoyloguanidine, method of obtaining them, their application in production of pharmaceutic and diagnostic agents and pharmaceutic agent as such
DE19546736A1 (en) * 1995-12-14 1997-06-19 Hoechst Ag Substituted chromanylsulfonyl (thio) ureas, process for their preparation and their use in the manufacture of pharmaceutical preparations
WO1997027183A1 (en) * 1996-01-26 1997-07-31 Fujisawa Pharmaceutical Co., Ltd. Guanidine derivatives
DE19621319A1 (en) * 1996-05-28 1997-12-04 Hoechst Ag Bis-ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent and medicament containing them
DE19622370A1 (en) * 1996-06-04 1997-12-11 Hoechst Ag Ortho-substituted benzoylguanidines, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
DE19737224A1 (en) 1997-08-27 1999-03-18 Hoechst Marion Roussel De Gmbh Pharmaceutical preparation for cardiovascular treatment
DE19738604A1 (en) * 1997-09-04 1999-03-11 Hoechst Marion Roussel De Gmbh Use of Na<+>/H<+> exchange inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB966816A (en) * 1961-09-05 1964-08-19 Ciba Ltd New guanidines and process for their preparation
US3780027A (en) 1970-04-29 1973-12-18 Merck & Co Inc Anthranilic acid derivatives
ATE158278T1 (en) * 1992-02-15 1997-10-15 Hoechst Ag ORTHO-SUBSTITUTED BENZOYLGUANIDINES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICATION OR DIAGNOSTIC AND A MEDICINE CONTAINING THEM
DK0603650T3 (en) * 1992-12-16 1997-10-20 Hoechst Ag 3,5-Substituted aminobenzoylguanidines, their method of preparation, their use as a drug or diagnostic, and drug containing them.
DE4318658A1 (en) * 1993-06-04 1994-12-08 Hoechst Ag Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, and medicament containing them

Also Published As

Publication number Publication date
HU9501925D0 (en) 1995-08-28
CZ169295A3 (en) 1996-05-15
CA2152878A1 (en) 1995-12-30
PL309386A1 (en) 1996-01-08
FI953173A (en) 1995-12-30
EP0690048A1 (en) 1996-01-03
TW273545B (en) 1996-04-01
JPH0812643A (en) 1996-01-16
DE4422685A1 (en) 1996-01-04
AU2330095A (en) 1996-01-11
HUT72413A (en) 1996-04-29
NZ272449A (en) 1996-07-26
SI9500211A (en) 1996-02-29
IL114377A0 (en) 1995-10-31
CN1119183A (en) 1996-03-27
ZA955342B (en) 1996-02-13
FI953173A0 (en) 1995-06-27
NO952596L (en) 1996-01-02
SK84195A3 (en) 1996-10-02

Similar Documents

Publication Publication Date Title
NO973850D0 (en) Phenyl-substituted alkenylcarboxylic acid guanidides; processes for their preparation, their use as a drug or diagnostic as well as drugs containing them
DK0771788T3 (en) Substituted sulfonimidamides, processes for their preparation, use thereof as a drug or diagnostic agent, and
NO972211D0 (en) Sulfonamide-substituted chromanes, their preparation, their use as a drug or diagnostic, and drugs containing the chromanes
NO962063L (en) Fluorophenyl-substituted alkenylcarboxylic acid guanidines, process for their preparation, their use as a drug or diagnostic as well as drug containing them
NO962006L (en) Substituted benzyloxycarbonylguanidines, process for their preparation, their use as drug or diagnostic as well as drug containing them
NO952596D0 (en) Ortho-amino-substituted benzoyl guandines, processes for their preparation, their use as a drug or diagnostic as well as drugs containing them
NO960364L (en) Basic-substituted benzolguanidines, process for their preparation, their use as a drug or diagnostic, and drug containing the compound
NO972433D0 (en) Substituted 2-naphthoylguanidines, processes for their preparation, their use as a drug or diagnostic, and medicaments containing the compounds
NO20022801D0 (en) Substituted norbornylamino derivatives, process for their preparation, their use as a drug or diagnostic as well as drugs containing these
NO960627L (en) Substituted benzene sulfonylureas, processes for their preparation, their use as a medicament or diagnostic, and drugs containing them
NO964053D0 (en) Substituted benzoylguanidines, processes for their preparation, their use as a drug or diagnostic, and medicaments containing the compounds
NO962999L (en) 4-Fluoroalkyl-substituted benzoylguanidines, processes for their preparation, their use as a drug or diagnostic, as well as drugs containing them
NO972527D0 (en) Ortho-substituted benzoylguanidines, their preparation, their use as a drug or diagnostic as well as drugs containing the benzoylguanidines
DK1097140T3 (en) Imidazole derivatives with biphenyl substitution, process for their preparation, their use as a drug or diagnostic and drug containing them
NO983577D0 (en) Sulfonamide-substituted compounds, processes for their preparation, their use as a drug or diagnostic, as well as drugs containing the compound
NO972434D0 (en) Substituted 1-Naphthoylguanidines, Methods of Preparation thereof, Their Use as a Drug or Diagnostic, and Medicines Containing the Compounds
NO973486D0 (en) Substituted indanylidine acetylguanidines, process for their preparation, their use as medicaments or diagnostics and medicaments containing the compounds
NO964812D0 (en) Sulfonylamino-substituted benzoylguanidines, their preparation, their use as a drug or diagnostic, and drugs containing the compounds
NO954739D0 (en) Substituted benzoylguanidines, processes for their preparation, their use as a drug or diagnostic, and drugs containing these compounds
NO972793D0 (en) Ortho-substituted benzoylguanidines, their preparation, their use as a drug or diagnostic, and medicaments containing the compounds
NO972406D0 (en) Bis-ortho-substituted benzoylguanidines, processes for their preparation, their use as a drug or diagnostic, and medicaments containing the compounds
NO964903D0 (en) Substituted benzenedicarboxylic acid diguanidide, process for their preparation, their use as a drug or diagnostic as well as drug containing them
NO980564D0 (en) Sulfonamide-substituted compounds, method of preparation, use as a medicament or diagnostic and drug obtained are described.
NO964904D0 (en) Substituted benzenedicarboxylic acid diguanidines, process for their preparation, their use as a drug or diagnostic as well as drugs containing them
DK0729954T3 (en) Substituted thiophenylsulfonylureas and thioureas, processes for their preparation, their use as a drug or diagnostic, and drugs containing them