NO952521L - Fluorocarbon emulsions - Google Patents

Fluorocarbon emulsions

Info

Publication number
NO952521L
NO952521L NO952521A NO952521A NO952521L NO 952521 L NO952521 L NO 952521L NO 952521 A NO952521 A NO 952521A NO 952521 A NO952521 A NO 952521A NO 952521 L NO952521 L NO 952521L
Authority
NO
Norway
Prior art keywords
drug
increasing
fluorocarbon
fluorocarbon emulsions
organs
Prior art date
Application number
NO952521A
Other languages
Norwegian (no)
Other versions
NO952521D0 (en
Inventor
Robert J Kaufman
Thomas J Richard
Original Assignee
Hemagen Pfc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemagen Pfc filed Critical Hemagen Pfc
Publication of NO952521D0 publication Critical patent/NO952521D0/en
Publication of NO952521L publication Critical patent/NO952521L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Medikamentavleveringseraulsjoner som Inneholder emulgerte partikler av en fluorkarbon, en olje i vann, et overflateaktivt middel og et medikament oppløselig-gjort 1 emulsjonen. Sammensetninger og metoder blir tllvelebragt for redusering av toksisitet, økning av målretting eller selektivitet mot visse organer, og økning av avsetning og retensjon av det ønskede medikamentet 1 disse målorganene, og dermed øke effekt av medikamenter.Drug delivery emulsions containing emulsified particles of a fluorocarbon, an oil in water, a surfactant and a drug solubilized in the emulsion. Compositions and methods are provided for reducing toxicity, increasing targeting or selectivity towards certain organs, and increasing deposition and retention of the desired drug in these target organs, thereby increasing drug efficacy.

NO952521A 1992-12-24 1995-06-22 Fluorocarbon emulsions NO952521L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99666192A 1992-12-24 1992-12-24
PCT/US1993/010209 WO1994014415A1 (en) 1992-12-24 1993-10-25 Fluorocarbon emulsions

Publications (2)

Publication Number Publication Date
NO952521D0 NO952521D0 (en) 1995-06-22
NO952521L true NO952521L (en) 1995-06-22

Family

ID=25543160

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952521A NO952521L (en) 1992-12-24 1995-06-22 Fluorocarbon emulsions

Country Status (7)

Country Link
JP (1) JPH08504811A (en)
CN (1) CN1093283A (en)
AU (1) AU5539294A (en)
CA (1) CA2151491A1 (en)
IL (1) IL107449A0 (en)
NO (1) NO952521L (en)
WO (1) WO1994014415A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436425B1 (en) 1988-11-16 2002-08-20 Mdv Technologies, Inc. Method and non-gelling composition for inhibiting post-surgical adhesions
US5346703A (en) 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US5667809A (en) * 1995-06-07 1997-09-16 Alliance Pharmaceutical Corp. Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents
US5874481A (en) * 1995-06-07 1999-02-23 Alliance Pharmaceutical Corp. Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents
US5843470A (en) 1995-10-06 1998-12-01 Mdv Technologies, Inc. Method and composition for inhibiting post-surgical adhesions
US5733526A (en) * 1995-12-14 1998-03-31 Alliance Pharmaceutical Corp. Hydrocarbon oil/fluorochemical preparations and methods of use
US5980936A (en) * 1997-08-07 1999-11-09 Alliance Pharmaceutical Corp. Multiple emulsions comprising a hydrophobic continuous phase
WO1999032151A1 (en) * 1997-12-23 1999-07-01 Alliance Pharmaceutical Corporation Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions
JP2001300287A (en) * 2000-04-20 2001-10-30 Nof Corp Perfluorocarbon emulsifying preparation
WO2002076441A1 (en) * 2001-03-21 2002-10-03 University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
WO2003062198A1 (en) * 2002-01-24 2003-07-31 Barnes Jewish Hospital Integrin targeted imaging agents
JP2004331487A (en) * 2003-02-28 2004-11-25 Topcon Corp Optical member and its manufacturing method
GT200500310A (en) * 2004-11-19 2006-06-19 ORGANIC COMPOUNDS
SA06270147B1 (en) 2005-06-09 2009-12-22 نوفارتيس ايه جي Process for the Synthesis Of 5-(methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine
US9000048B2 (en) 2006-11-28 2015-04-07 Wisconsin Alumni Research Foundation Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics
RU2557933C1 (en) * 2014-03-27 2015-07-27 Сергей Юрьевич Пушкин Method for preparing sterile nanoemulsion of perfluororganic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59130813A (en) * 1983-01-14 1984-07-27 Green Cross Corp:The Adminiculum for chemotherapy of cancer
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
JPH0372423A (en) * 1989-05-26 1991-03-27 Green Cross Corp:The Emulsified formation containing perfluorocarbon compound

Also Published As

Publication number Publication date
WO1994014415A1 (en) 1994-07-07
JPH08504811A (en) 1996-05-28
NO952521D0 (en) 1995-06-22
CA2151491A1 (en) 1994-07-07
AU5539294A (en) 1994-07-19
IL107449A0 (en) 1994-01-25
CN1093283A (en) 1994-10-12

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