NO951110D0 - Prolonged release pharmaceutical preparations of trimethazidine - Google Patents

Prolonged release pharmaceutical preparations of trimethazidine

Info

Publication number
NO951110D0
NO951110D0 NO951110A NO951110A NO951110D0 NO 951110 D0 NO951110 D0 NO 951110D0 NO 951110 A NO951110 A NO 951110A NO 951110 A NO951110 A NO 951110A NO 951110 D0 NO951110 D0 NO 951110D0
Authority
NO
Norway
Prior art keywords
trimethazidine
pharmaceutical preparations
release pharmaceutical
prolonged release
liberation
Prior art date
Application number
NO951110A
Other languages
Norwegian (no)
Other versions
NO951110L (en
NO306450B1 (en
Inventor
Bruno Huet De Barochez
Patrick Genty
Alain Cuine
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NO951110D0 publication Critical patent/NO951110D0/en
Publication of NO951110L publication Critical patent/NO951110L/en
Publication of NO306450B1 publication Critical patent/NO306450B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compsn. for prolonged liberation of trimetazidine (II) or its salts, uses a polymer insoluble in water and a plasticiser to control liberation.
NO951110A 1994-03-24 1995-03-23 Prolonged release pharmaceutical preparations of trimethazidine NO306450B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403434A FR2717687B1 (en) 1994-03-24 1994-03-24 Pharmaceutical compositions for the sustained release of trimetazidine after oral administration.

Publications (3)

Publication Number Publication Date
NO951110D0 true NO951110D0 (en) 1995-03-23
NO951110L NO951110L (en) 1995-09-25
NO306450B1 NO306450B1 (en) 1999-11-08

Family

ID=9461361

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951110A NO306450B1 (en) 1994-03-24 1995-03-23 Prolonged release pharmaceutical preparations of trimethazidine

Country Status (15)

Country Link
EP (1) EP0673649B1 (en)
JP (1) JP3017040B2 (en)
CN (1) CN1056057C (en)
AT (1) ATE216583T1 (en)
AU (1) AU684893B2 (en)
CA (1) CA2145248C (en)
DE (1) DE69526467T2 (en)
DK (1) DK0673649T3 (en)
ES (1) ES2176296T3 (en)
FI (1) FI116881B (en)
FR (1) FR2717687B1 (en)
NO (1) NO306450B1 (en)
NZ (1) NZ270791A (en)
PT (1) PT673649E (en)
ZA (1) ZA952418B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2802424B1 (en) * 1999-12-17 2002-02-15 Adir MATRIX TABLET FOR THE EXTENDED RELEASE OF TRIMETAZIDINE AFTER ORAL ADMINISTRATION
ATE442852T1 (en) * 2000-10-05 2009-10-15 Usv Ltd DELAYED-RELEASE MEDICINAL COMPRISING TRIMETAZIDINE AND METHOD FOR THE PRODUCTION
FR2818549B1 (en) * 2000-12-26 2003-02-07 Servier Lab SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF TRIMETAZIDINE
HUP0500382A3 (en) * 2001-11-21 2008-03-28 Themis Lab Private Ltd Sustained release pharmaceutical compositions containing microbeads of trimetazidine dihydrochloride and process for producing them
FR2885807B1 (en) * 2005-05-18 2008-05-16 Mg Pharma SOLID PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE, AND PREPARATION METHOD
WO2007116243A2 (en) * 2006-04-10 2007-10-18 Mintails Limited Method for treating fibromyalgia and related conditions
EP2200591A2 (en) 2007-09-11 2010-06-30 Ranbaxy Laboratories Limited Controlled release pharmaceutical dosage forms of trimetazidine
JP2012515757A (en) 2009-01-20 2012-07-12 マイクロ ラブス リミテッド Trimetazidine controlled release solid pharmaceutical composition and method for producing the same
HUE027498T2 (en) * 2009-01-30 2016-10-28 Lupin Ltd Pharmaceutical compositions of trimetazidine
TR201001902A2 (en) 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Trimetazidine tablets with extended release
ES2508490T3 (en) 2010-05-04 2014-10-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulation of trimetazidine with different release profiles
EP2386302A1 (en) 2010-05-11 2011-11-16 Ranbaxy Laboratories Limited A controlled release pharmaceutical dosage form of trimetazidine and processes for the preparation thereof
BG1345U1 (en) * 2010-05-20 2010-08-31 "Адифарм" Ад Modified-release pharmaceutical formulation
EP2491930A1 (en) 2011-02-25 2012-08-29 Deva Holding Anonim Sirketi Pharmaceutical combination of betahistine and trimetazidine
CN102133195A (en) * 2011-03-17 2011-07-27 王国栋 Trimetazidine dihydrochloride sustained control release pellet and preparation method thereof
CN102319225B (en) * 2011-09-23 2013-04-03 广州白云山光华制药股份有限公司 Trimetazidine hydrochloride sustained release tablet and preparation method thereof
FR2986431B1 (en) * 2012-02-03 2017-03-17 Servier Lab PROLONGED RELEASE OF TRIMETAZIDINE PHARMACEUTICAL COMPOSITION, PROCESS FOR THE PRODUCTION THEREOF AND USE IN THERAPEUTIC TREATMENTS
CN102764261A (en) * 2012-07-30 2012-11-07 沈阳药科大学 Oral composition controlling release of trimetazidine dihydrochloride and preparation method of oral composition
CN103565751A (en) * 2013-10-17 2014-02-12 广州帝奇医药技术有限公司 Long-acting sustained-release pellet and preparation method thereof
US20190381034A1 (en) * 2018-06-14 2019-12-19 Ming Fang Pharmaceutical composition and method for acute on chronic liver failure and related liver diseases
CN110237053A (en) * 2019-07-26 2019-09-17 湖北欣泽霏药业有限公司 A kind of trimetazidine hydrochloride sustained-release pellet and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490963B1 (en) * 1980-09-30 1986-04-18 Science Union & Cie NOVEL THERAPEUTIC COMPOSITION WITH ANTI-ISCHEMIC ACTION CONTAINING TRIMETHOXY 2, 3, 4-BENZYL 1-PIPERAZINE
DE3686275T2 (en) * 1985-01-11 1993-03-18 Teijin Ltd PREPARED PRODUCTS WITH DELAYED RELEASE.
JPH0625055B2 (en) * 1985-03-18 1994-04-06 日本ケミフア株式会社 Persistent tablets
US5260066A (en) * 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
US5417983A (en) * 1992-02-19 1995-05-23 Sagami Chemical Research Center Drug release controlling material responsive to changes in temperature

Also Published As

Publication number Publication date
EP0673649A1 (en) 1995-09-27
FI951357A0 (en) 1995-03-22
ATE216583T1 (en) 2002-05-15
AU684893B2 (en) 1998-01-08
NZ270791A (en) 1996-07-26
FR2717687B1 (en) 1996-06-14
CA2145248C (en) 2004-01-06
NO951110L (en) 1995-09-25
CN1124140A (en) 1996-06-12
CN1056057C (en) 2000-09-06
JPH07258086A (en) 1995-10-09
ZA952418B (en) 1995-12-18
FI951357A (en) 1995-09-25
DE69526467D1 (en) 2002-05-29
JP3017040B2 (en) 2000-03-06
NO306450B1 (en) 1999-11-08
FI116881B (en) 2006-03-31
CA2145248A1 (en) 1995-09-25
DK0673649T3 (en) 2002-08-05
FR2717687A1 (en) 1995-09-29
AU1502995A (en) 1995-10-05
DE69526467T2 (en) 2002-12-05
EP0673649B1 (en) 2002-04-24
PT673649E (en) 2002-08-30
ES2176296T3 (en) 2002-12-01

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