US5739135A
(en)
*
|
1993-09-03 |
1998-04-14 |
Bristol-Myers Squibb Company |
Inhibitors of microsomal triglyceride transfer protein and method
|
US5567718A
(en)
*
|
1994-08-11 |
1996-10-22 |
Hoechst Marion Roussel Inc. |
2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors
|
US5919795A
(en)
*
|
1995-06-07 |
1999-07-06 |
Pfizer Inc. |
Biphenyl-2-carboxylic acid-tetrahydro-isoquinolin-6-yl amide derivatives, their preparation and their use as inhibitors of microsomal triglyceride transfer protein and/or apolipoprotein B (Apo B) secretion
|
EP0832069B1
(en)
*
|
1995-06-07 |
2003-03-05 |
Pfizer Inc. |
BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION
|
PT832069E
(en)
*
|
1995-06-07 |
2003-06-30 |
Pfizer |
BIPHENYL-2-CARBOXYLIC ACID TETRAHYDRO-ISOQUINOLIN-6-YLIDATE AND THEIR PREPARATION AND ITS USE AS MICROSOMAL TRIGLYCERID TRANSFERENCE PROTEIN INHIBITORS AND / OR APOLIPOPROTEIN B SECRECY (APO B)
|
SK283408B6
(en)
*
|
1995-06-07 |
2003-07-01 |
Pfizer Inc. |
Amides and pharmaceutical preparations based on them
|
ES2218660T3
(en)
*
|
1996-01-16 |
2004-11-16 |
Bristol-Myers Squibb Company |
AROMATIC INHIBITORS CONFORMALLY RESTRICTED FROM THE MICROSOMAL TRIGLICERID TRANSFER PROTEIN AND PROCEDURE.
|
WO1997041111A1
(en)
*
|
1996-04-30 |
1997-11-06 |
Pfizer Inc. |
Processes and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2h-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide
|
US5827875A
(en)
*
|
1996-05-10 |
1998-10-27 |
Bristol-Myers Squibb Company |
Inhibitors of microsomal triglyceride transfer protein and method
|
US5885983A
(en)
*
|
1996-05-10 |
1999-03-23 |
Bristol-Myers Squibb Company |
Inhibitors of microsomal triglyceride transfer protein and method
|
JP2002513379A
(en)
*
|
1996-07-24 |
2002-05-08 |
ブリストル―マイヤーズ・スクイブ・カンパニー |
Treatment of tumors with high LDL requirements using MTP inhibitors
|
US5883109A
(en)
*
|
1996-07-24 |
1999-03-16 |
Bristol-Myers Squibb Company |
Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
|
US5989873A
(en)
*
|
1996-09-24 |
1999-11-23 |
Vinayagamoorthy; Thuraiayah |
Method of detecting gene expression and/or of preventing such expression in cells
|
WO1998023593A1
(en)
*
|
1996-11-27 |
1998-06-04 |
Pfizer Inc. |
Apo b-secretion/mtp inhibitory amides
|
US5760246A
(en)
|
1996-12-17 |
1998-06-02 |
Biller; Scott A. |
Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
|
WO1998027979A1
(en)
|
1996-12-20 |
1998-07-02 |
Bristol-Myers Squibb Company |
Heterocyclic inhibitors of microsomal triglyceride transfer protein and method
|
US6066653A
(en)
*
|
1997-01-17 |
2000-05-23 |
Bristol-Myers Squibb Co. |
Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs
|
EP0989852A4
(en)
*
|
1997-01-17 |
2002-11-13 |
Bristol Myers Squibb Co |
Method for treating atherosclerosis with an mpt inhibitor and cholesterol lowering drugs
|
US5929091A
(en)
*
|
1997-03-12 |
1999-07-27 |
Warner-Lambert Company |
Method of lowering plasma levels of lipoprotein(a)
|
WO1998054135A1
(en)
|
1997-05-30 |
1998-12-03 |
Meiji Seika Kaisha, Ltd. |
Nitrogenous heterocyclic compounds and hyperlipemia remedy containing the same
|
US5968950A
(en)
*
|
1997-06-23 |
1999-10-19 |
Pfizer Inc |
Apo B-secretion/MTP inhibitor hydrochloride salt
|
US6767739B2
(en)
*
|
2001-07-30 |
2004-07-27 |
Isis Pharmaceuticals Inc. |
Antisense modulation of microsomal triglyceride transfer protein expression
|
US6218524B1
(en)
*
|
1997-09-16 |
2001-04-17 |
Eurona Medical Ab |
Genetic polymorphisms in the microsomal triglyceride transfer protein promoter and uses thereof
|
JP2959765B2
(en)
|
1997-12-12 |
1999-10-06 |
日本たばこ産業株式会社 |
3-piperidyl-4-oxoquinazoline derivative and pharmaceutical composition containing the same
|
EP1085846A2
(en)
|
1998-06-08 |
2001-03-28 |
Advanced Medicine, Inc. |
Multibinding inhibitors of microsomal triglyceride transferase protein
|
US6780883B2
(en)
|
1998-11-05 |
2004-08-24 |
Warner-Lambert Company |
Amide inhibitors of microsomal triglyceride transfer protein
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
KR20020005662A
(en)
|
1999-04-09 |
2002-01-17 |
기따자또 이찌로 |
Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same
|
SE9902987D0
(en)
*
|
1999-08-24 |
1999-08-24 |
Astra Pharma Prod |
Novel compounds
|
KR100879647B1
(en)
*
|
2000-03-06 |
2009-01-20 |
아카디아 파마슈티칼스 인코포레이티드 |
Azacyclic compounds for use in the treatment of serotonin related diseases
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
AU2001262185A1
(en)
*
|
2000-04-10 |
2001-10-23 |
Novartis Ag |
Substituted (hetero)aryl carboxamide derivatives as microsomal triglyceride transfer protein (mtp) and apolipoprotein b (apo b) secretion
|
GB0011838D0
(en)
*
|
2000-05-17 |
2000-07-05 |
Astrazeneca Ab |
Chemical compounds
|
GB0013383D0
(en)
*
|
2000-06-01 |
2000-07-26 |
Glaxo Group Ltd |
Therapeutic benzamide derivatives
|
DE10030375A1
(en)
*
|
2000-06-21 |
2002-01-03 |
Bayer Ag |
Use of MTP inhibitors to lower ppTRL
|
JO2654B1
(en)
|
2000-09-04 |
2012-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Polyarylcarboxamides useful as lipid lowering agents
|
JO2409B1
(en)
|
2000-11-21 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Biphenylcarboxamides useful as lipid lowering agents
|
FR2816940A1
(en)
*
|
2000-11-23 |
2002-05-24 |
Lipha |
New 4-(biphenyl carbonylamino) piperidine derivatives are microsomal triglyceride transfer protein and apoprotein B secretion inhibitors used for treating e.g. hypercholesterolemia and obesity
|
AR031930A1
(en)
*
|
2000-12-22 |
2003-10-08 |
Schering Corp |
MCH ANTAGONISTS AND ITS USE IN THE TREATMENT OF OBESITY
|
GB0104050D0
(en)
|
2001-02-19 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
GB0107228D0
(en)
|
2001-03-22 |
2001-05-16 |
Astrazeneca Ab |
Chemical compounds
|
US6774112B2
(en)
|
2001-04-11 |
2004-08-10 |
Bristol-Myers Squibb Company |
Amino acid complexes of C-aryl glucosides for treatment of diabetes and method
|
IL158516A0
(en)
|
2001-06-28 |
2004-05-12 |
Pfizer Prod Inc |
Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (mtp) and/or apolipoprotein b (apo b) secretion
|
CA2463908A1
(en)
*
|
2001-10-18 |
2003-04-24 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
US7238671B2
(en)
*
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
SE0103818D0
(en)
|
2001-11-15 |
2001-11-15 |
Astrazeneca Ab |
Chemical compounds
|
WO2003043624A1
(en)
|
2001-11-16 |
2003-05-30 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
AU2002360561A1
(en)
*
|
2001-12-11 |
2003-06-23 |
Sepracor, Inc. |
4-substituted piperidines, and methods of use thereof
|
BR0215429A
(en)
*
|
2001-12-28 |
2004-12-14 |
Acadia Pharm Inc |
Compound of formula I and its uses, activity inhibition methods and monoamine receptor activation inhibition method, treatment methods, genetic polymorphism identification method and patient identification method
|
US6747048B2
(en)
|
2002-05-08 |
2004-06-08 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
JP4478563B2
(en)
*
|
2002-05-14 |
2010-06-09 |
プレゼント インヴェストメンツ エルエルシー |
Transmission signal forming method
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
US7253186B2
(en)
*
|
2002-06-24 |
2007-08-07 |
Carl-Magnus Andersson |
N-substituted piperidine derivatives as serotonin receptor agents
|
NZ537522A
(en)
*
|
2002-06-24 |
2006-07-28 |
Acadia Pharm Inc |
N-substituted piperidine derivatives as serotonin receptor agents
|
US7538222B2
(en)
*
|
2002-06-24 |
2009-05-26 |
Acadia Pharmaceuticals, Inc. |
N-substituted piperidine derivatives as serotonin receptor agents
|
TW200409637A
(en)
|
2002-06-26 |
2004-06-16 |
Glaxo Group Ltd |
Compounds
|
DE60332856D1
(en)
*
|
2002-10-23 |
2010-07-15 |
Bristol Myers Squibb Co |
GLYCINNITRIL BASED DIPEPTIDYLPEPTIDASE IV INHIBITORS
|
US7098235B2
(en)
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
EP2009000B1
(en)
|
2003-01-16 |
2011-06-08 |
Acadia Pharmaceuticals Inc. |
Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
|
JP2006516620A
(en)
*
|
2003-01-24 |
2006-07-06 |
ブリストル−マイヤーズ スクイブ カンパニー |
Cycloalkyl-containing anilide ligands in thyroid receptors.
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
US7557143B2
(en)
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
SE0301369D0
(en)
|
2003-05-09 |
2003-05-09 |
Astrazeneca Ab |
Chemical compounds
|
US7459474B2
(en)
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7767828B2
(en)
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
CA2545311C
(en)
|
2003-11-12 |
2012-01-03 |
Phenomix Corporation |
Heterocyclic boronic acid compounds
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7253283B2
(en)
|
2004-01-16 |
2007-08-07 |
Bristol-Myers Squibb Company |
Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US7273881B2
(en)
|
2004-01-16 |
2007-09-25 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
AP2006003685A0
(en)
|
2004-02-04 |
2006-08-31 |
Pfizer Prod Inc |
Substituted quinoline compounds
|
WO2005087234A1
(en)
|
2004-03-05 |
2005-09-22 |
The Trustees Of The University Of Pennsylvania |
Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects
|
US20080280922A1
(en)
*
|
2004-04-09 |
2008-11-13 |
Marc Alois Celine Maria Engelen |
Intermittent Dosing Regimen For Overweight and Obese Subjects
|
TWI396686B
(en)
*
|
2004-05-21 |
2013-05-21 |
Takeda Pharmaceutical |
Cyclic amide derivative, and its production and use
|
US20050261278A1
(en)
|
2004-05-21 |
2005-11-24 |
Weiner David M |
Selective serotonin receptor inverse agonists as therapeutics for disease
|
US7820695B2
(en)
*
|
2004-05-21 |
2010-10-26 |
Acadia Pharmaceuticals, Inc. |
Selective serotonin receptor inverse agonists as therapeutics for disease
|
JP2008504523A
(en)
*
|
2004-06-25 |
2008-02-14 |
ザ リサーチ ファウンデーション オブ ステート ユニバーシティ オブ ニューヨーク |
Fluorescence assay for MTP activity
|
TW200611704A
(en)
*
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
US7145040B2
(en)
*
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
KR101389246B1
(en)
|
2004-07-15 |
2014-04-24 |
브리스톨-마이어스스퀴브컴파니 |
Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
|
AR051446A1
(en)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
C-ARYL GLUCOSIDS AS SELECTIVE INHIBITORS OF GLUCOSE CONVEYORS (SGLT2)
|
MX2007003433A
(en)
*
|
2004-09-27 |
2007-08-06 |
Acadia Pharm Inc |
Synthesis of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4- (2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms.
|
US7790899B2
(en)
*
|
2004-09-27 |
2010-09-07 |
Acadia Pharmaceuticals, Inc. |
Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
|
SE0403117D0
(en)
*
|
2004-12-21 |
2004-12-21 |
Astrazeneca Ab |
New compounds 1
|
US7635699B2
(en)
*
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7589088B2
(en)
*
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7317024B2
(en)
|
2005-01-13 |
2008-01-08 |
Bristol-Myers Squibb Co. |
Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
EP1879881A2
(en)
|
2005-04-14 |
2008-01-23 |
Bristol-Myers Squibb Company |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type i
|
FR2884831B1
(en)
*
|
2005-04-22 |
2007-08-10 |
Merck Sante Soc Par Actions Si |
METHOD FOR SCREENING MTP INHIBITORY COMPOUNDS
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7825139B2
(en)
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
KR20080026117A
(en)
*
|
2005-05-26 |
2008-03-24 |
브리스톨-마이어스 스큅 컴퍼니 |
N-terminally modified glp-1 receptor modulators
|
JP2008542255A
(en)
*
|
2005-05-27 |
2008-11-27 |
ファイザー・プロダクツ・インク |
Combination of cannabinoid-1 receptor antagonist and microsomal triglyceride transfer protein inhibitor for the treatment of obesity or maintenance of weight loss
|
US7888381B2
(en)
|
2005-06-14 |
2011-02-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
|
US20070093468A1
(en)
*
|
2005-10-18 |
2007-04-26 |
Wisler Gerald L |
Methods for treating disorders associated with hyperlipidemia in a mammal
|
EP2487154B1
(en)
|
2005-10-31 |
2013-10-16 |
Bristol-Myers Squibb Company |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
|
JP2007169627A
(en)
*
|
2005-11-28 |
2007-07-05 |
Konica Minolta Medical & Graphic Inc |
Photocurable composition, active ray-curable type ink composition and image forming method
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
JP2009523177A
(en)
*
|
2006-01-11 |
2009-06-18 |
ブリストル−マイヤーズ スクイブ カンパニー |
Human glucagon-like peptide-1 modulator and its use in the treatment of diabetes and related conditions
|
US8110681B2
(en)
|
2006-03-17 |
2012-02-07 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Compounds for the treatment of spinal muscular atrophy and other uses
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
WO2007124461A2
(en)
|
2006-04-20 |
2007-11-01 |
Amgen Inc. |
Glp-1 compounds
|
WO2007140191A2
(en)
|
2006-05-23 |
2007-12-06 |
Theracos, Inc. |
Glucose transport inhibitors and methods of use
|
US20100022457A1
(en)
*
|
2006-05-26 |
2010-01-28 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
US20080044326A1
(en)
*
|
2006-07-04 |
2008-02-21 |
Esencia Co., Ltd. |
Sterilizer for baby products
|
WO2008005910A2
(en)
|
2006-07-06 |
2008-01-10 |
Bristol-Myers Squibb Company |
Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
JP5525261B2
(en)
|
2006-10-24 |
2014-06-18 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
MTP-inhibiting tetrahydro-naphthalene-1-carboxylic acid derivative
|
JO2653B1
(en)
|
2006-10-24 |
2012-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Piperidine Or Piperazine Substituted Tetrahydro-Naphthalene-1-Carboxylic Acid Mtp Inhibiting Compounds.apoB
|
EP2094692B1
(en)
|
2006-11-01 |
2012-11-28 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, ap-1 and/or nf-kappab activity and use thereof
|
JP2010508358A
(en)
|
2006-11-01 |
2010-03-18 |
ブリストル−マイヤーズ スクイブ カンパニー |
Glucocorticoid receptor, AP-1 and / or modulator of NF-κB activity, and use thereof
|
WO2008057862A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
US7994190B2
(en)
|
2006-11-01 |
2011-08-09 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
EP2120927A1
(en)
*
|
2006-12-21 |
2009-11-25 |
Aegerion Pharmaceuticals, Inc. |
Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor
|
UY30892A1
(en)
*
|
2007-02-07 |
2008-09-02 |
Smithkline Beckman Corp |
AKT ACTIVITY INHIBITORS
|
ES2423485T3
(en)
|
2007-03-19 |
2013-09-20 |
Acadia Pharmaceuticals Inc. |
Associations of 5-HT2A inverse agonists and antagonists with antipsychotics
|
PE20090185A1
(en)
|
2007-03-22 |
2009-02-28 |
Bristol Myers Squibb Co |
PHARMACEUTICAL FORMULATIONS CONTAINING AN SGLT2 INHIBITOR
|
CN101687873A
(en)
|
2007-04-17 |
2010-03-31 |
百时美施贵宝公司 |
11 beta-hydroxysteroid dehydrogenase type i inhibitors with annelated heterocycles
|
PE20090696A1
(en)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
CRYSTALLINE FORMS OF SAXAGLIPTIN AND PROCESSES FOR PREPARING THEM
|
EP2147008A2
(en)
*
|
2007-05-18 |
2010-01-27 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for preparing same
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
WO2009018065A2
(en)
*
|
2007-07-27 |
2009-02-05 |
Bristol-Myers Squibb Company |
Novel glucokinase activators and methods of using same
|
KR101107425B1
(en)
|
2007-08-23 |
2012-01-19 |
테라코스, 인코포레이티드 |
Benzylbenzene derivatives and methods of use
|
TW200918062A
(en)
*
|
2007-09-12 |
2009-05-01 |
Wyeth Corp |
Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists
|
US20090082388A1
(en)
*
|
2007-09-21 |
2009-03-26 |
Acadia Pharmaceuticals Inc. |
Co-administration of pimavanserin with other agents
|
AU2008304231A1
(en)
*
|
2007-09-27 |
2009-04-02 |
Albany Molecular Research, Inc. |
Isoindoline compounds for the treatment of spinal muscular atrophy and other uses
|
EP2209780B1
(en)
|
2007-11-01 |
2014-01-01 |
Bristol-Myers Squibb Company |
Nonsteroidal compounds useful as modulators of glucocorticoid receptor ap-1 and/or nf- kappa b activity and use thereof
|
US20090197947A1
(en)
*
|
2008-02-01 |
2009-08-06 |
The Research Foundation Of State University Of New York |
Medicaments and methods for lowering plasma lipid levels and screening drugs
|
EP2247597A1
(en)
|
2008-02-07 |
2010-11-10 |
Bristol-Myers Squibb Company |
Fused heteroaryl modulators of glucocorticoid receptor, ap-1, and/or nf-kb activity and use thereof
|
WO2009133834A1
(en)
*
|
2008-04-28 |
2009-11-05 |
塩野義製薬株式会社 |
Keto-amide derivative having inhibitory activity on endothelial lipase
|
US9156812B2
(en)
|
2008-06-04 |
2015-10-13 |
Bristol-Myers Squibb Company |
Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
|
JP2011525537A
(en)
|
2008-06-24 |
2011-09-22 |
ブリストル−マイヤーズ スクイブ カンパニー |
Cyclopentathiophene modulators of glucocorticoid receptor, AP-1, and / or NF-κB activity and uses thereof
|
US20100035862A1
(en)
*
|
2008-06-25 |
2010-02-11 |
Abbott Laboratories |
Novel aza-cyclic indole-2-carboxamides and methods of use thereof
|
CA2730734C
(en)
*
|
2008-07-15 |
2017-04-25 |
Theracos, Inc. |
Deuterated 2,3,4-trihydroxy-tetrahydropyranyl-benzylbenzene compounds having sodium glucose cotransporter inhibitory activity
|
MA32998B1
(en)
*
|
2009-01-30 |
2012-01-02 |
Glaxosmithkline Llc |
N-{{1-s) -2-amino-1-[(3-fluorophenyl) methyl]} ethyl-5-chloro-4 (4-chloro-1-methyl-1h-pyrazol-5 -yl) Crystalline theophenicarboxamide
|
WO2010127099A2
(en)
|
2009-04-29 |
2010-11-04 |
Amarin Corporation Plc |
Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
|
EP2429296B1
(en)
*
|
2009-05-12 |
2017-12-27 |
Albany Molecular Research, Inc. |
7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
|
MX2011011901A
(en)
|
2009-05-12 |
2012-01-20 |
Albany Molecular Res Inc |
Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof.
|
JP5739415B2
(en)
*
|
2009-05-12 |
2015-06-24 |
ブリストル−マイヤーズ スクウィブ カンパニー |
(S) -7-([1,2,4] triazolo [1,5-a] pyridin-6-yl) -4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydroisoquinoline Crystal forms and uses thereof
|
BR112012011274A2
(en)
|
2009-11-13 |
2016-04-12 |
Astrazeneca Uk Ltd |
reduced mass metformin formulation and its combination
|
ES2693686T3
(en)
|
2009-11-13 |
2018-12-13 |
Astrazeneca Ab |
Immediate-release tablet formulations
|
HUE040486T2
(en)
|
2009-11-13 |
2019-03-28 |
Astrazeneca Ab |
Bilayer tablet formulations
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
EP2558461B1
(en)
|
2010-04-14 |
2015-12-02 |
Bristol-Myers Squibb Company |
Novel glucokinase activators and methods of using same
|
AU2011254658B2
(en)
|
2010-05-19 |
2016-02-18 |
Sandoz Ag |
Purification of posaconazole and of posaconazole intermediates
|
WO2011144656A1
(en)
|
2010-05-19 |
2011-11-24 |
Sandoz Ag |
Preparation of posaconazole intermediates
|
EP2571847B1
(en)
|
2010-05-19 |
2016-09-21 |
Sandoz AG |
Process for the preparation of chiral hydrazides
|
WO2011153712A1
(en)
|
2010-06-12 |
2011-12-15 |
Theracos, Inc. |
Crystalline form of benzylbenzene sglt2 inhibitor
|
CA2804926C
(en)
|
2010-07-09 |
2019-01-08 |
James Trinca Green |
Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
|
EP2600716A4
(en)
|
2010-08-03 |
2014-02-19 |
Beth Israel Hospital |
Methods and compositions for treatment of metabolic disorders
|
TWI631963B
(en)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
Compositions comprising and methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
US9493428B2
(en)
|
2011-06-16 |
2016-11-15 |
Sandoz Ag |
Process for the preparation of a chiral compound
|
CN108440614A
(en)
|
2012-11-20 |
2018-08-24 |
莱西肯医药有限公司 |
The inhibitor of sodium glucose cotransporter 1
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
US10118890B2
(en)
|
2014-10-10 |
2018-11-06 |
The Research Foundation For The State University Of New York |
Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration
|
DK3325444T3
(en)
|
2015-07-20 |
2021-10-04 |
Acadia Pharm Inc |
PROCEDURES FOR THE PREPARATION OF N- (4-FLUOROBENZYL) -N- (1-METHYLPIPERIDIN-4-YL) -N '- (4- (2-METHYLPROPYLOXY) PHENYLMETHYL) CARBAMID AND DETSMAL PARTHOLE
|
US10953000B2
(en)
|
2016-03-25 |
2021-03-23 |
Acadia Pharmaceuticals Inc. |
Combination of pimavanserin and cytochrome P450 modulators
|
WO2017165635A1
(en)
|
2016-03-25 |
2017-09-28 |
Acadia Pharmaceuticals Inc. |
Combination of pimavanserin and cytochrome p450 modulators
|
WO2018118626A1
(en)
|
2016-12-20 |
2018-06-28 |
Acadia Pharmaceuticals Inc. |
Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis
|
US11135211B2
(en)
|
2017-04-28 |
2021-10-05 |
Acadia Pharmaceuticals Inc. |
Pimavanserin for treating impulse control disorder
|
WO2019046167A1
(en)
|
2017-08-30 |
2019-03-07 |
Acadia Pharmaceuticals Inc. |
Formulations of pimavanserin
|
CN107935854A
(en)
*
|
2017-10-30 |
2018-04-20 |
广东莱佛士制药技术有限公司 |
A kind of synthetic method of γ dialkyl group N-Propyl Bromide
|
TW201938171A
(en)
|
2017-12-15 |
2019-10-01 |
匈牙利商羅特格登公司 |
Tricyclic compounds as vasopressin V1a receptor antagonists
|
AU2019346497A1
(en)
|
2018-09-26 |
2021-04-08 |
Lexicon Pharmaceuticals, Inc. |
Crystalline forms of n-(1 -((2-(dimethylamino)ethyl)amino)-2-m ethyl-1 -oopropan-2-yl)-4-(4-(2-methyl-5- (2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2h-pyran-2-yl)benzyl) phenl)butanamide and methods of their synthesis
|
EP4188372A1
(en)
|
2020-07-29 |
2023-06-07 |
Amryt Pharmaceuticals Inc. |
Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients
|
WO2022187463A1
(en)
|
2021-03-03 |
2022-09-09 |
Amryt Pharmaceuticals Inc. |
Methods for treating familial chylomicronemia syndrome
|