NO943232L - Aromatic carboxylic acid derivatives - Google Patents
Aromatic carboxylic acid derivativesInfo
- Publication number
- NO943232L NO943232L NO943232A NO943232A NO943232L NO 943232 L NO943232 L NO 943232L NO 943232 A NO943232 A NO 943232A NO 943232 A NO943232 A NO 943232A NO 943232 L NO943232 L NO 943232L
- Authority
- NO
- Norway
- Prior art keywords
- carboxylic acid
- acid derivatives
- aromatic carboxylic
- image
- dermatological
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
Abstract
The compounds of the formula <IMAGE> wherein R<1> is a radical of the formulae <IMAGE> and R<2>-R<10> have the meaning mentioned in the description, can be used as medicaments, particularly for dermatological and oncological indications.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH261893 | 1993-09-02 | ||
CH196094 | 1994-06-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO943232D0 NO943232D0 (en) | 1994-09-01 |
NO943232L true NO943232L (en) | 1995-03-03 |
NO308579B1 NO308579B1 (en) | 2000-10-02 |
Family
ID=25689113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO943232A NO308579B1 (en) | 1993-09-02 | 1994-09-01 | Use of aromatic carboxylic acid derivatives for the preparation of pharmaceutical preparations for the therapy and prophylaxis of light and age-related skin lesions, and for the promotion of wound healing, as well as new compounds |
Country Status (20)
Country | Link |
---|---|
US (2) | US5700836A (en) |
EP (1) | EP0641759B1 (en) |
JP (1) | JP2602629B2 (en) |
KR (1) | KR100335540B1 (en) |
CN (1) | CN1049423C (en) |
AT (1) | ATE174322T1 (en) |
AU (1) | AU680668B2 (en) |
CA (1) | CA2129773C (en) |
CZ (1) | CZ288426B6 (en) |
DE (1) | DE59407431D1 (en) |
DK (1) | DK0641759T3 (en) |
ES (1) | ES2126684T3 (en) |
FI (1) | FI113261B (en) |
GR (1) | GR3029437T3 (en) |
HU (1) | HU222345B1 (en) |
IL (1) | IL110808A (en) |
NO (1) | NO308579B1 (en) |
NZ (1) | NZ264327A (en) |
RU (1) | RU2130009C1 (en) |
UA (1) | UA43317C2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7655699B1 (en) | 1992-04-22 | 2010-02-02 | Eisai Inc. | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
DE4320920C1 (en) * | 1993-06-24 | 1994-06-16 | Goldschmidt Ag Th | New silane cpds. used as surfactant in aq. media - comprise ether and hydrophilic gps., and are stable against hydrolysis in acid and alkali |
FR2719041B1 (en) * | 1994-04-26 | 1996-05-31 | Cird Galderma | New polyene compounds, pharmaceutical and cosmetic compositions containing them and uses. |
US7115728B1 (en) * | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
PT873295E (en) * | 1995-10-06 | 2003-08-29 | Ligand Pharm Inc | SELECTIVE RXR MODULATORS FOR DIMENSIONS FOR THEIR USE |
AU8588798A (en) * | 1997-07-25 | 1999-02-16 | Institut Pasteur | Human peroxisome proliferator activated receptor gamma (ppargamma) gene re gulatory sequences and uses therefor |
JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of emphysema using rar selective retinoid antagonists |
KR100353310B1 (en) * | 2000-03-27 | 2002-09-18 | 송웅재 | A stone-tomb for constructing |
KR100385492B1 (en) * | 2000-08-10 | 2003-05-27 | 주식회사 지오지 | Method of manufacturing a pipe connecting socket |
EP1935869A1 (en) * | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
JP4118675B2 (en) * | 2000-10-02 | 2008-07-16 | エフ.ホフマン−ラ ロシュ アーゲー | A new retinoid for the treatment of emphysema |
US20030073712A1 (en) * | 2001-07-23 | 2003-04-17 | Bing Wang | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods |
KR20070004730A (en) * | 2004-02-17 | 2007-01-09 | 다이나미스 테라퓨틱스, 인코포레이티드 | Fructoseamine 3 kinase and the formation of collagen and elastin |
JP4683858B2 (en) | 2004-05-14 | 2011-05-18 | スリーエム イノベイティブ プロパティズ カンパニー | Article support |
CN102575220B (en) | 2009-09-03 | 2015-09-16 | 贝克顿·迪金森公司 | For the method and composition of direct chemical cracking |
MX361414B (en) | 2010-09-01 | 2018-12-05 | Univ Jefferson | Composition and method for muscle repair and regeneration. |
WO2012076842A1 (en) * | 2010-12-09 | 2012-06-14 | University Of Durham | Synthetic retinoids for control of cell differentiation |
WO2013019653A1 (en) * | 2011-07-29 | 2013-02-07 | Tempero Pharmaceuticals, Inc. | Compounds and methods |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU77254A1 (en) * | 1977-05-04 | 1979-01-18 | ||
US4326055A (en) * | 1977-12-22 | 1982-04-20 | Hoffmann-La Roche Inc. | Stilbene derivatives |
DK159967C (en) * | 1977-12-22 | 1991-06-03 | Hoffmann La Roche | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE STYLE BENDER DERIVATIVES |
DE3202100A1 (en) * | 1982-01-23 | 1983-08-04 | Basf Ag, 6700 Ludwigshafen | SUBSTITUTED 4-HYDROXYANILIDES, ITS PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
ZA854828B (en) * | 1984-07-27 | 1986-03-26 | Hoffmann La Roche | Phenyl nonatetraenoic acid derivatives |
FR2569689B1 (en) * | 1984-09-05 | 1990-11-16 | Oreal | NOVEL BENZONORBORNENE DERIVATIVES, PREPARATION METHODS THEREOF, AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM |
DE3434944A1 (en) * | 1984-09-22 | 1986-04-03 | Basf Ag, 6700 Ludwigshafen | L-SUBSTITUTED TETRALIN DERIVATIVES, THEIR PRODUCTION AND USE |
US4889847A (en) * | 1986-11-03 | 1989-12-26 | Ortho Pharmaceutical Corporation | Prevention of glucocorticoid-induced skin atrophy |
US5019569A (en) * | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
CA1298309C (en) * | 1987-11-06 | 1992-03-31 | Michael Klaus | Benzocycloheptene derivatives |
EP0983991B1 (en) * | 1992-04-22 | 2003-12-17 | Ligand Pharmaceuticals, Inc. | Compounds having selectivity for retinoid x receptors |
US5324840A (en) * | 1992-06-11 | 1994-06-28 | Allergan, Inc. | Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects |
WO1995004036A1 (en) * | 1993-01-11 | 1995-02-09 | Ligand Pharmaceuticals Inc. | Compounds having selective activity for retinoid x receptors, and means for modulation of processes mediated by retinoid x receptors |
-
1994
- 1994-08-09 CA CA002129773A patent/CA2129773C/en not_active Expired - Fee Related
- 1994-08-18 EP EP94112886A patent/EP0641759B1/en not_active Expired - Lifetime
- 1994-08-18 AT AT94112886T patent/ATE174322T1/en not_active IP Right Cessation
- 1994-08-18 DE DE59407431T patent/DE59407431D1/en not_active Expired - Fee Related
- 1994-08-18 ES ES94112886T patent/ES2126684T3/en not_active Expired - Lifetime
- 1994-08-18 DK DK94112886T patent/DK0641759T3/en active
- 1994-08-25 AU AU71486/94A patent/AU680668B2/en not_active Ceased
- 1994-08-29 IL IL11080894A patent/IL110808A/en not_active IP Right Cessation
- 1994-08-29 JP JP6203653A patent/JP2602629B2/en not_active Expired - Fee Related
- 1994-08-29 HU HU9402480A patent/HU222345B1/en not_active IP Right Cessation
- 1994-08-29 NZ NZ264327A patent/NZ264327A/en unknown
- 1994-09-01 CN CN94115650A patent/CN1049423C/en not_active Expired - Fee Related
- 1994-09-01 KR KR1019940021952A patent/KR100335540B1/en not_active IP Right Cessation
- 1994-09-01 CZ CZ19942105A patent/CZ288426B6/en not_active IP Right Cessation
- 1994-09-01 RU RU94031754A patent/RU2130009C1/en not_active IP Right Cessation
- 1994-09-01 UA UA94095764A patent/UA43317C2/en unknown
- 1994-09-01 NO NO943232A patent/NO308579B1/en unknown
- 1994-09-02 FI FI944045A patent/FI113261B/en active
-
1996
- 1996-10-21 US US08/734,222 patent/US5700836A/en not_active Expired - Fee Related
-
1997
- 1997-08-01 US US08/904,522 patent/US6610877B1/en not_active Expired - Fee Related
-
1999
- 1999-02-17 GR GR990400520T patent/GR3029437T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUT71473A (en) | 1995-11-28 |
US5700836A (en) | 1997-12-23 |
CN1105981A (en) | 1995-08-02 |
RU94031754A (en) | 1996-07-20 |
ATE174322T1 (en) | 1998-12-15 |
JP2602629B2 (en) | 1997-04-23 |
IL110808A0 (en) | 1994-11-11 |
AU7148694A (en) | 1995-03-16 |
FI944045A (en) | 1995-03-03 |
RU2130009C1 (en) | 1999-05-10 |
HU9402480D0 (en) | 1994-10-28 |
UA43317C2 (en) | 2001-12-17 |
US6610877B1 (en) | 2003-08-26 |
NZ264327A (en) | 1996-02-27 |
EP0641759B1 (en) | 1998-12-09 |
CN1049423C (en) | 2000-02-16 |
FI944045A0 (en) | 1994-09-02 |
JPH07112952A (en) | 1995-05-02 |
FI113261B (en) | 2004-03-31 |
CZ288426B6 (en) | 2001-06-13 |
HU222345B1 (en) | 2003-06-28 |
IL110808A (en) | 2003-03-12 |
CA2129773A1 (en) | 1995-03-03 |
DK0641759T3 (en) | 1999-08-16 |
KR100335540B1 (en) | 2002-10-25 |
ES2126684T3 (en) | 1999-04-01 |
EP0641759A1 (en) | 1995-03-08 |
NO308579B1 (en) | 2000-10-02 |
KR950008468A (en) | 1995-04-17 |
DE59407431D1 (en) | 1999-01-21 |
NO943232D0 (en) | 1994-09-01 |
CZ210594A3 (en) | 1995-06-14 |
GR3029437T3 (en) | 1999-05-28 |
CA2129773C (en) | 2007-05-01 |
AU680668B2 (en) | 1997-08-07 |
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