NO942977D0 - Piperazine and piperidine derivatives and their use as antipsychotic agents - Google Patents

Piperazine and piperidine derivatives and their use as antipsychotic agents

Info

Publication number
NO942977D0
NO942977D0 NO942977A NO942977A NO942977D0 NO 942977 D0 NO942977 D0 NO 942977D0 NO 942977 A NO942977 A NO 942977A NO 942977 A NO942977 A NO 942977A NO 942977 D0 NO942977 D0 NO 942977D0
Authority
NO
Norway
Prior art keywords
piperazine
piperidine derivatives
antipsychotic agents
antipsychotic
agents
Prior art date
Application number
NO942977A
Other languages
Norwegian (no)
Other versions
NO942977L (en
Inventor
Henry Mark Norman
Frank Navas
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO942977D0 publication Critical patent/NO942977D0/en
Publication of NO942977L publication Critical patent/NO942977L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO942977A 1992-02-12 1994-08-11 Piperazine and piperidine derivatives and their use as antipsychotic agents NO942977L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929202915A GB9202915D0 (en) 1992-02-12 1992-02-12 Chemical compounds
PCT/GB1993/000285 WO1993016073A1 (en) 1992-02-12 1993-02-11 Piperazine and piperidine derivatives, and their use as antipsychotics

Publications (2)

Publication Number Publication Date
NO942977D0 true NO942977D0 (en) 1994-08-11
NO942977L NO942977L (en) 1994-10-10

Family

ID=10710223

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942977A NO942977L (en) 1992-02-12 1994-08-11 Piperazine and piperidine derivatives and their use as antipsychotic agents

Country Status (16)

Country Link
EP (1) EP0625978A1 (en)
JP (1) JPH07503723A (en)
KR (1) KR950700290A (en)
AU (1) AU3460393A (en)
CA (1) CA2117434A1 (en)
CZ (1) CZ194994A3 (en)
FI (1) FI943718A0 (en)
GB (1) GB9202915D0 (en)
HU (1) HUT72309A (en)
IL (1) IL104690A0 (en)
MX (1) MX9300786A (en)
NO (1) NO942977L (en)
RU (1) RU94038064A (en)
SK (1) SK96494A3 (en)
WO (1) WO1993016073A1 (en)
ZA (1) ZA93958B (en)

Families Citing this family (30)

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US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
RU2118322C1 (en) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-dihydro-1,4-benzodioxine-5-yl-pyrerazine derivatives and salts thereof
US5874429A (en) * 1993-12-24 1999-02-23 Suntory Limited Benzothiazine derivative
US6001827A (en) 1993-12-24 1999-12-14 Suntory Limited Benzothiazine derivative
JPH0912562A (en) * 1995-06-22 1997-01-14 Suntory Ltd Substituted benzothiazine derivative
KR100366962B1 (en) * 1993-12-24 2003-03-03 산토리 가부시키가이샤 Benzothiazine derivative
WO1996014297A1 (en) * 1994-11-04 1996-05-17 Sumitomo Pharmaceuticals Company, Limited Novel lactam derivatives
PT732332E (en) * 1995-03-17 2002-06-28 Aventis Pharma Inc BENZOTIENILPIPERAZINES SUBSTITUTED ITS USE AS MEDICINES AND PROCESSES FOR THEIR PREPARATION
US6087364A (en) * 1998-01-29 2000-07-11 Warner-Lambert Company Dopamine D4 receptor antagonists
DE19814084B4 (en) 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2 agonist-containing transdermal therapeutic system for the treatment of Parkinson's syndrome and process for its preparation
US7030142B1 (en) 1999-04-06 2006-04-18 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites
JP2002541098A (en) * 1999-04-06 2002-12-03 セプラコア インコーポレーテッド Methods and compositions for treating neuroleptic disorders and related disorders using ziprasidone metabolites
AR028685A1 (en) * 2000-06-14 2003-05-21 Lundbeck & Co As H INDOL DERIVATIVES
DE10234673B4 (en) 2002-07-30 2007-08-16 Schwarz Pharma Ag Hot-melt TTS for the administration of rotigotine and process for its preparation, and use of rotigotine in the manufacture of a hot-melt TTS
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
EP2295061A1 (en) 2002-08-22 2011-03-16 Dainippon Sumitomo Pharma Co., Ltd. Agent for treatment of schizophrenia
DE10261696A1 (en) 2002-12-30 2004-07-15 Schwarz Pharma Ag Device for the transdermal administration of rotigotine base
JP4624261B2 (en) 2003-06-23 2011-02-02 大日本住友製薬株式会社 Treatment for senile dementia
DE10334188B4 (en) 2003-07-26 2007-07-05 Schwarz Pharma Ag Use of rotigotine to treat depression
US20070160537A1 (en) 2004-02-20 2007-07-12 Takeo Ishiyama In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia
KR20090098999A (en) * 2007-01-03 2009-09-18 코텍스 파마슈티칼스, 인크. 3-substituted-[1,2,3]-benzotriazinone compounds for enhancing glutamatergic synaptic responses
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder
US8981095B2 (en) 2011-07-28 2015-03-17 Mapi Pharma Ltd. Intermediate compounds and process for the preparation of lurasidone and salts thereof
RU2669393C2 (en) * 2013-07-31 2018-10-11 Мерк Патент Гмбх Oxoquinazolinyl-butanamide derivatives
CN105669665A (en) * 2016-03-15 2016-06-15 烟台贝森医药科技有限公司 Preparation method of perospirone
US11246905B2 (en) 2016-08-15 2022-02-15 President And Fellows Of Harvard College Treating infections using IdsD from Proteus mirabilis
CN115124464B (en) * 2022-07-04 2023-06-06 新乡学院 Quinoline diketone sulfonyl piperazine hybrid, and preparation method and application thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2258843B1 (en) * 1974-01-30 1977-09-09 Roussel Uclaf
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
JPH0625181B2 (en) * 1985-03-27 1994-04-06 住友製薬株式会社 New imide derivative
JP2660407B2 (en) * 1986-09-26 1997-10-08 住友製薬株式会社 New imide derivatives
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
NZ230045A (en) * 1988-08-05 1990-11-27 Janssen Pharmaceutica Nv 3-piperazinylbenzazole derivatives and pharmaceutical compositions
US4968792A (en) * 1989-09-25 1990-11-06 American Home Products Corporation Psychotropic benzisothiazole derivatives
JP2800953B2 (en) * 1990-07-06 1998-09-21 住友製薬株式会社 New imide derivatives

Also Published As

Publication number Publication date
HU9402343D0 (en) 1994-10-28
GB9202915D0 (en) 1992-03-25
AU3460393A (en) 1993-09-03
IL104690A0 (en) 1993-06-10
JPH07503723A (en) 1995-04-20
ZA93958B (en) 1994-08-11
CZ194994A3 (en) 1995-09-13
HUT72309A (en) 1996-04-29
WO1993016073A1 (en) 1993-08-19
SK96494A3 (en) 1995-07-11
RU94038064A (en) 1997-05-27
EP0625978A1 (en) 1994-11-30
FI943718A (en) 1994-08-11
NO942977L (en) 1994-10-10
FI943718A0 (en) 1994-08-11
MX9300786A (en) 1994-03-31
KR950700290A (en) 1995-01-16
CA2117434A1 (en) 1993-08-19

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