NO941347L - Process for the preparation of a human monoclonal antibody - Google Patents
Process for the preparation of a human monoclonal antibodyInfo
- Publication number
- NO941347L NO941347L NO941347A NO941347A NO941347L NO 941347 L NO941347 L NO 941347L NO 941347 A NO941347 A NO 941347A NO 941347 A NO941347 A NO 941347A NO 941347 L NO941347 L NO 941347L
- Authority
- NO
- Norway
- Prior art keywords
- crl
- antibodies
- human monoclonal
- cell lines
- preparation
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Cellelinjer er blitt fremstilt som utskiller humane, monoklonale antistoffer som er i stand til å bindes til molekyler av forskjellige bak- teriearter. Disse antistoffer er blitt funnet å være beskyttende mot letale utfordringer av forskjellige bakterieslekter. Farmasøytiske pre- parater inneholdende disse antistoffer, som kan være i kombinasjon med andre monoklonale antistoffer, blodplasma- fraksjoner og antimikrobielle midler, og den profylaktiske og terapeutiske bruk av slike preparater ved behand- ling av infeksjoner, er beskrevet. Før innlevering av foreliggende patentsøknad ble de her beskrevne, kontinuerlig transformerte, humane cellelinjer 9B10, 4F10, 4B9, 7D7 og 9C3, deponert ved American Type Culture Collection og gitt betegnelsene CRL 90O6, CRL 9007, CRL 9008, CRL 9009 og CRL 9239.Cell lines have been prepared which secrete human monoclonal antibodies capable of binding to molecules of various bacterial species. These antibodies have been found to be protective against lethal challenges of various bacterial genera. Pharmaceutical preparations containing these antibodies, which may be in combination with other monoclonal antibodies, blood plasma fractions and antimicrobial agents, and the prophylactic and therapeutic use of such preparations in the treatment of infections, are described. Prior to filing the present patent application, the continuously described human cell lines 9B10, 4F10, 4B9, 7D7 and 9C3 described herein were deposited with the American Type Culture Collection and designated CRL 90O6, CRL 9007, CRL 9008, CRL 9009 and CRL 9239.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO941347A NO941347D0 (en) | 1986-02-07 | 1994-04-14 | Process for the preparation of a human monoclonal antibody |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82800586A | 1986-02-07 | 1986-02-07 | |
US94449586A | 1986-12-19 | 1986-12-19 | |
NO870476A NO176924C (en) | 1986-02-07 | 1987-02-06 | Antibody preparation for non-therapeutic use |
NO941347A NO941347D0 (en) | 1986-02-07 | 1994-04-14 | Process for the preparation of a human monoclonal antibody |
Publications (2)
Publication Number | Publication Date |
---|---|
NO941347L true NO941347L (en) | 1987-08-10 |
NO941347D0 NO941347D0 (en) | 1994-04-14 |
Family
ID=27484149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO941347A NO941347D0 (en) | 1986-02-07 | 1994-04-14 | Process for the preparation of a human monoclonal antibody |
Country Status (1)
Country | Link |
---|---|
NO (1) | NO941347D0 (en) |
-
1994
- 1994-04-14 NO NO941347A patent/NO941347D0/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO941347D0 (en) | 1994-04-14 |
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