NO940261L - 5-membered heterocycles, process for the preparation thereof and drugs containing these compounds - Google Patents
5-membered heterocycles, process for the preparation thereof and drugs containing these compoundsInfo
- Publication number
- NO940261L NO940261L NO940261A NO940261A NO940261L NO 940261 L NO940261 L NO 940261L NO 940261 A NO940261 A NO 940261A NO 940261 A NO940261 A NO 940261A NO 940261 L NO940261 L NO 940261L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- preparation
- membered heterocycles
- drugs containing
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
Denne oppfinnelse vedrører 5-leddede heterocykler med den generelle formel. hvori. Xtil Xer definert som i krav 1, deres tautomerer, deres stereoisomerer innbefattet deres blandinger og deres salter, særlig deres fysiologisk aksepterbare salter med uorganiske eller organiske syrer eller baser, som har verdifulle farma-kologiske egenskaper, fortrinnsvis aggregeringshemmende virk-ninger, legemidler som inneholder forbindelsene og fremgangs-måter for deres fremstilling.This invention relates to 5-membered heterocycles of the general formula. where. Xtil Xer as defined in claim 1, their tautomers, their stereoisomers including their mixtures and their salts, in particular their physiologically acceptable salts with inorganic or organic acids or bases, which have valuable pharmacological properties, preferably anti-aggregation effects, drugs containing the compounds and methods of their preparation.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4302051A DE4302051A1 (en) | 1993-01-26 | 1993-01-26 | 5-membered heterocycles, process for their preparation and medicaments containing these compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
NO940261D0 NO940261D0 (en) | 1994-01-25 |
NO940261L true NO940261L (en) | 1994-07-27 |
Family
ID=6478937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO940261A NO940261L (en) | 1993-01-26 | 1994-01-25 | 5-membered heterocycles, process for the preparation thereof and drugs containing these compounds |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0608858A1 (en) |
JP (1) | JPH072851A (en) |
KR (1) | KR940018382A (en) |
CN (1) | CN1097753A (en) |
AU (1) | AU5398494A (en) |
BG (1) | BG98409A (en) |
CA (1) | CA2114178A1 (en) |
CZ (1) | CZ18194A3 (en) |
DE (1) | DE4302051A1 (en) |
FI (1) | FI940378A (en) |
HU (1) | HU9400217D0 (en) |
IL (1) | IL108436A0 (en) |
NO (1) | NO940261L (en) |
NZ (1) | NZ250762A (en) |
PL (1) | PL302018A1 (en) |
RU (1) | RU94002482A (en) |
SK (1) | SK8394A3 (en) |
ZA (1) | ZA94495B (en) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
ZA963391B (en) * | 1995-05-24 | 1997-10-29 | Du Pont Merck Pharma | Isoxazoline fibrinogen receptor antagonists. |
CA2229617A1 (en) * | 1995-10-20 | 1997-05-01 | Dr. Karl Thomae Gmbh | 5-membered heterocycles, medicaments containing these compounds, their use and processes for their preparation |
US6083986A (en) * | 1996-07-26 | 2000-07-04 | Icagen, Inc. | Potassium channel inhibitors |
US6333337B1 (en) | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
PL345247A1 (en) | 1998-07-01 | 2001-12-03 | Takeda Chemical Industries Ltd | Retinoid-associated receptor regulators |
WO2000047188A1 (en) * | 1999-02-11 | 2000-08-17 | Emisphere Technologies, Inc. | Oxadiazole compounds and compositions for delivering active agents |
US7084279B1 (en) | 1999-02-11 | 2006-08-01 | Emisphere Technologies Inc. | Oxadiazole compounds and compositions for delivering active agents |
EP1240147A1 (en) | 1999-12-21 | 2002-09-18 | Icagen, Inc. | Potassium channel inhibitors |
AU2000223275A1 (en) * | 2000-02-08 | 2001-08-20 | Yamanouchi Pharmaceutical Co..Ltd. | Novel triazole derivatives |
WO2001087855A1 (en) * | 2000-05-19 | 2001-11-22 | Yamanouchi Pharmaceutical Co., Ltd. | Triazole derivatives |
US6566380B2 (en) | 2000-07-25 | 2003-05-20 | Icagen, Inc. | Potassium channel inhibitors |
US6620849B2 (en) | 2000-07-26 | 2003-09-16 | Icafen, Inc. | Potassium channel inhibitors |
US6849634B2 (en) | 2000-12-21 | 2005-02-01 | Icagen | Potassium channel inhibitors |
US7223791B2 (en) * | 2001-06-26 | 2007-05-29 | Takeda Pharmaceutical Company Limited | Function regulator for retinoid relative receptor |
US7390813B1 (en) | 2001-12-21 | 2008-06-24 | Xenon Pharmaceuticals Inc. | Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents |
AU2003218028A1 (en) | 2002-03-08 | 2003-09-22 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
JP4926402B2 (en) | 2002-11-27 | 2012-05-09 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 1,2,3-Triazoleamide derivatives as cytokine inhibitors |
US7078419B2 (en) | 2003-03-10 | 2006-07-18 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
BRPI0409686A (en) | 2003-04-24 | 2006-07-04 | Incyte Corp | aza spiro alkane derivatives as metalloprotease inhibitors |
EP2316827B1 (en) | 2003-07-30 | 2016-01-27 | Xenon Pharmaceuticals Inc. | Piperazine derivatives and their use as therapeutic agents |
ES2360292T3 (en) | 2003-12-03 | 2011-06-02 | Boehringer Ingelheim Pharmaceuticals Inc. | 1,2,3-TRIAZOL AMIDA DERIVATIVES AS INHIBITORS OF CYTOKIN PRODUCTION. |
PT1725544E (en) | 2004-03-09 | 2009-07-02 | Boehringer Ingelheim Pharma | 3-[4-heterocyclyl-1,2,3-triazol-1-yl]-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases |
WO2005108387A2 (en) | 2004-05-03 | 2005-11-17 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
US7485657B2 (en) | 2004-05-12 | 2009-02-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
EP2269610A3 (en) | 2004-09-20 | 2011-03-09 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
CA2580845A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase |
MX2007003318A (en) | 2004-09-20 | 2007-05-18 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes. |
BRPI0515488A (en) | 2004-09-20 | 2008-07-29 | Xenon Pharmaceuticals Inc | heterocyclic derivatives and their use as therapeutic agents |
AU2005286647A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
CN101084207A (en) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
MX2007003327A (en) | 2004-09-20 | 2007-06-05 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase. |
US7531560B2 (en) | 2004-11-10 | 2009-05-12 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
AP2007004047A0 (en) | 2005-01-20 | 2007-06-30 | Pfizer Ltd | Substituted triazole derivatives as oxtocin antagonists |
JP2009513563A (en) | 2005-06-03 | 2009-04-02 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors |
TW200811164A (en) * | 2006-05-12 | 2008-03-01 | Jerini Ag | New heterocyclic compounds for the inhibition of integrins and use thereof |
US7910108B2 (en) | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
TW200813018A (en) | 2006-06-09 | 2008-03-16 | Astrazeneca Ab | Novel compounds |
RU2009110254A (en) | 2006-08-24 | 2010-09-27 | Новартис АГ (CH) | 2- (PYRAZIN-2-IL) THIAZOLE DERIVATIVES AND 2- (1H-PYRAZOL-3-IL) THYRAZOL AND COMPOUNDS CONNECTED WITH IT AS STEAROIL-SOA INHIBERATOUS AND SMOKE |
PL2090570T3 (en) | 2006-09-05 | 2012-03-30 | Kyowa Hakko Kirin Co Ltd | Imidazole derivative |
CA2685266C (en) | 2007-04-27 | 2014-01-28 | Purdue Pharma L.P. | Trpv1 antagonists and uses thereof for the treatment of prevention of pain, ui and ulcer, ibd, or ibs in an animal |
US8119661B2 (en) | 2007-09-11 | 2012-02-21 | Astrazeneca Ab | Piperidine derivatives and their use as muscarinic receptor modulators |
CA2801074A1 (en) | 2010-06-04 | 2011-12-08 | Albany Molecular Research, Inc. | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
EP2723732B1 (en) | 2011-06-22 | 2017-01-18 | Purdue Pharma LP | Trpv1 antagonists including dihydroxy substituent and uses thereof |
US9593106B2 (en) | 2013-02-07 | 2017-03-14 | Heptares Therapeutics Limited | Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists |
GB201810071D0 (en) | 2018-06-19 | 2018-08-08 | Univ Oslo Hf | Compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL98757A (en) * | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
DE4124942A1 (en) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-LOW HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENTS CONTAINING SUCH COMPOUNDS |
-
1993
- 1993-01-26 DE DE4302051A patent/DE4302051A1/en not_active Withdrawn
-
1994
- 1994-01-24 SK SK83-94A patent/SK8394A3/en unknown
- 1994-01-24 BG BG98409A patent/BG98409A/en unknown
- 1994-01-25 RU RU94002482/04A patent/RU94002482A/en unknown
- 1994-01-25 CA CA002114178A patent/CA2114178A1/en not_active Abandoned
- 1994-01-25 ZA ZA94495A patent/ZA94495B/en unknown
- 1994-01-25 NO NO940261A patent/NO940261L/en unknown
- 1994-01-25 CN CN94100575A patent/CN1097753A/en active Pending
- 1994-01-25 JP JP6006295A patent/JPH072851A/en active Pending
- 1994-01-25 KR KR1019940001441A patent/KR940018382A/en not_active Application Discontinuation
- 1994-01-25 PL PL94302018A patent/PL302018A1/en unknown
- 1994-01-25 HU HU9400217A patent/HU9400217D0/en unknown
- 1994-01-26 EP EP94101125A patent/EP0608858A1/en not_active Withdrawn
- 1994-01-26 FI FI940378A patent/FI940378A/en not_active Application Discontinuation
- 1994-01-26 CZ CZ94181A patent/CZ18194A3/en unknown
- 1994-01-26 IL IL10843694A patent/IL108436A0/en unknown
- 1994-01-26 NZ NZ250762A patent/NZ250762A/en unknown
- 1994-01-27 AU AU53984/94A patent/AU5398494A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2114178A1 (en) | 1994-07-27 |
CZ18194A3 (en) | 1994-11-16 |
DE4302051A1 (en) | 1994-07-28 |
NO940261D0 (en) | 1994-01-25 |
CN1097753A (en) | 1995-01-25 |
EP0608858A1 (en) | 1994-08-03 |
BG98409A (en) | 1994-09-30 |
HU9400217D0 (en) | 1994-05-30 |
ZA94495B (en) | 1995-07-25 |
AU5398494A (en) | 1994-08-04 |
IL108436A0 (en) | 1994-04-12 |
PL302018A1 (en) | 1994-08-08 |
FI940378A (en) | 1994-07-27 |
NZ250762A (en) | 1995-08-28 |
KR940018382A (en) | 1994-08-16 |
RU94002482A (en) | 1996-08-27 |
SK8394A3 (en) | 1995-02-08 |
FI940378A0 (en) | 1994-01-26 |
JPH072851A (en) | 1995-01-06 |
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