NO934653D0 - Use of thrombin inhibitors for inhibition of ocular fibrin formation - Google Patents

Use of thrombin inhibitors for inhibition of ocular fibrin formation

Info

Publication number
NO934653D0
NO934653D0 NO934653D NO934653D NO934653D0 NO 934653 D0 NO934653 D0 NO 934653D0 NO 934653 D NO934653 D NO 934653D NO 934653 D NO934653 D NO 934653D NO 934653 D0 NO934653 D0 NO 934653D0
Authority
NO
Norway
Prior art keywords
inhibition
thrombin inhibitors
fibrin formation
ocular
ocular fibrin
Prior art date
Application number
NO934653D
Other languages
Norwegian (no)
Inventor
Juergen Roemisch
Eric Paul Paques
Eckhard Schueler
Original Assignee
Behringswerke Aktiengeschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringswerke Aktiengeschaft filed Critical Behringswerke Aktiengeschaft
Publication of NO934653D0 publication Critical patent/NO934653D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO934653D 1992-12-17 1993-12-16 Use of thrombin inhibitors for inhibition of ocular fibrin formation NO934653D0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4242655A DE4242655A1 (en) 1992-12-17 1992-12-17 Use of thrombin inhibitors to inhibit ocular fibrin formation

Publications (1)

Publication Number Publication Date
NO934653D0 true NO934653D0 (en) 1993-12-16

Family

ID=6475561

Family Applications (2)

Application Number Title Priority Date Filing Date
NO934653A NO934653L (en) 1992-12-17 1993-12-16 Use of thrombin inhibitors for inhibition of ocular fibrin formation
NO934653D NO934653D0 (en) 1992-12-17 1993-12-16 Use of thrombin inhibitors for inhibition of ocular fibrin formation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO934653A NO934653L (en) 1992-12-17 1993-12-16 Use of thrombin inhibitors for inhibition of ocular fibrin formation

Country Status (7)

Country Link
EP (1) EP0603112A1 (en)
JP (1) JPH06228006A (en)
KR (1) KR940013532A (en)
AU (1) AU675090B2 (en)
CA (1) CA2111644A1 (en)
DE (1) DE4242655A1 (en)
NO (2) NO934653L (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510369A (en) * 1994-07-22 1996-04-23 Merck & Co., Inc. Pyrrolidine thrombin inhibitors
US5629324A (en) * 1995-04-10 1997-05-13 Merck & Co., Inc. Thrombin inhibitors
US5798377A (en) * 1996-10-21 1998-08-25 Merck & Co., Inc. Thrombin inhibitors
AR027686A1 (en) * 2000-03-20 2003-04-09 Knoll Ag USE OF INHIBITING SUBSTANCES OF COAGULATION IN THE EXTRACORPORE TREATMENT OF BLOOD
CA2431588A1 (en) 2000-12-18 2002-06-27 Merck & Co., Inc. Benzylamine derivatives and their use as thrombin inhibitors
US6528503B2 (en) 2000-12-18 2003-03-04 Merck & Co., Inc. Thrombin inhibitors
US7144899B2 (en) 2001-02-09 2006-12-05 Merck & Co., Inc. Thrombin inhibitors
US7084134B2 (en) 2002-05-02 2006-08-01 Merk & Co., Inc. Thrombin inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8203887D0 (en) * 1982-06-23 1982-06-23 Kabivitrum Ab NEW TROMBIN INHIBITIVE ASSOCIATIONS
DE3445532A1 (en) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn HIRUDIN-PA, DESULFATOHIRUDINE-PA, METHOD FOR PRODUCTION AND PHARMACEUTICAL AGENTS THAT CONTAIN THESE ACTIVE SUBSTANCES
GB8504025D0 (en) * 1985-02-16 1985-03-20 Biopharm Ltd Hyaluronidase
PT84170B (en) * 1986-01-24 1989-03-30 Sanofi Sa N-ALPHA-ARIL-SULFONYLAMINOACYL D-AMIDINEFENYL-ALANINAMID D NON-SUBSTITUTED DERIVATIVES PROCESS FOR THE PREPARATION OF N ALPHA-SUBSTITUTED DERIVATIVES
NL8902454A (en) * 1989-10-03 1991-05-01 Stichting Centraal Lab MUTANTS OF THE HUMANE PLASMINOGENIC ACTIVATOR INHIBITOR 1 (PAI-1), THEIR PREPARATION AND USE, AND RECOMBINANT POLYNUCLEOTIDES INCLUDING GENETIC INFORMATION CODING FOR THESE MUTANTS.
TW201303B (en) * 1990-07-05 1993-03-01 Hoffmann La Roche
DE4111394A1 (en) * 1991-04-09 1992-10-15 Behringwerke Ag AMIDINOPHENYLALANINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AND MEANS THEREOF

Also Published As

Publication number Publication date
CA2111644A1 (en) 1994-06-18
DE4242655A1 (en) 1994-06-23
KR940013532A (en) 1994-07-15
NO934653L (en) 1994-06-20
JPH06228006A (en) 1994-08-16
EP0603112A1 (en) 1994-06-22
AU5243693A (en) 1994-06-30
AU675090B2 (en) 1997-01-23

Similar Documents

Publication Publication Date Title
FI951059A (en) Sulfonamide inhibitors of HIV aspartyl portease
NO982809L (en) Drugs of thrombin inhibitors
NO974722D0 (en) THF-containing sulfonamide inhibitors of aspartyl protease
NO974744D0 (en) Oxygen-heterocycle-containing sulfonamide inhibitors of aspartyl protease
NO960723D0 (en) Inhibitors of TNF-alpha secretion
ZA939285B (en) Inhibitors of aspartyl protease
LV12102A (en) Inhibitors of rotamase functions
NO954427D0 (en) HIV protease inhibitors useful for the treatment of AIDS
NO20003332D0 (en) Midisin precursor of aspartyl protease inhibitors
FI941519A0 (en) Heterocyclic inhibitors of farnesyl protein transferase
FI964137A (en) Inhibitors of rotamase enzyme activity
AU2251892A (en) Inhibitors of picornavirus proteases
NO934653D0 (en) Use of thrombin inhibitors for inhibition of ocular fibrin formation
NO934721D0 (en) HIV protease inhibitors useful for the treatment of AIDS
FI925144A (en) The use of inhibitors for the production of chromogens and the addition of chromogens
NO940190L (en) Use of alpha-ketoglutarate
GB9208596D0 (en) Inhibitors of thrombin
NO931629D0 (en) CLEANING PLASMINOGEN ACTIVATOR INHIBITORS 2 BY IMMUNAFFINITY CHROMATOGRAPHY
NO922191D0 (en) NEW THROMBIN INHIBITORS
GB9109601D0 (en) Inhibitors of thrombin
ITMI930345A1 (en) N-ACYL-PEPTIDES INHIBITORS OF PROTEIN-KINASES
NO914562D0 (en) PROCEDURE FOR THE PREPARATION OF PROTEASE INHIBITORS
NO920025L (en) SYNERGIME OF HIV REVERSTRANSCRIPTASE INHIBITORS
NO940997D0 (en) Guanidinyl-substituted heterocyclic thrombin inhibitors
ZA938470B (en) Sulfonamide inhibitors of aspartyl protease