NO934515L - Innskudd-mutasjoner i mycobakterier - Google Patents

Innskudd-mutasjoner i mycobakterier

Info

Publication number
NO934515L
NO934515L NO934515A NO934515A NO934515L NO 934515 L NO934515 L NO 934515L NO 934515 A NO934515 A NO 934515A NO 934515 A NO934515 A NO 934515A NO 934515 L NO934515 L NO 934515L
Authority
NO
Norway
Prior art keywords
mycobacteria
gene
mutant
mutations
deposit
Prior art date
Application number
NO934515A
Other languages
English (en)
Norwegian (no)
Inventor
William R Jacobs
Barry Bloom
Ganjam V Kalpana
Jeffrey D Cirillo
Original Assignee
Einstein Coll Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Einstein Coll Med filed Critical Einstein Coll Med
Publication of NO934515L publication Critical patent/NO934515L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
NO934515A 1991-06-13 1993-12-09 Innskudd-mutasjoner i mycobakterier NO934515L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71465691A 1991-06-13 1991-06-13
US80670691A 1991-12-12 1991-12-12
PCT/US1992/004706 WO1992022326A1 (en) 1991-06-13 1992-06-02 Insertional mutations in mycobacteria

Publications (1)

Publication Number Publication Date
NO934515L true NO934515L (no) 1994-02-02

Family

ID=27109189

Family Applications (2)

Application Number Title Priority Date Filing Date
NO934515D NO934515D0 (no) 1991-06-13 1993-12-09 Innskudd-mutasjoner i mycobakterier
NO934515A NO934515L (no) 1991-06-13 1993-12-09 Innskudd-mutasjoner i mycobakterier

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO934515D NO934515D0 (no) 1991-06-13 1993-12-09 Innskudd-mutasjoner i mycobakterier

Country Status (7)

Country Link
EP (2) EP0972839A1 (de)
JP (1) JPH06511145A (de)
AU (2) AU2189392A (de)
CA (1) CA2111217A1 (de)
FI (1) FI935566A0 (de)
NO (2) NO934515D0 (de)
WO (1) WO1992022326A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566121B1 (en) 1991-06-13 2003-05-20 Albert Einstein College Of Medicine Of Yeshiva University Insertional mutations in mycobacteria
ATE407945T1 (de) 1993-11-23 2008-09-15 Univ California Reichlich vorhandene extrazelluläre produkte und methoden zu ihrer herstellung sowie ihre verwendung
US7300660B2 (en) 1993-11-23 2007-11-27 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
US6752993B1 (en) 1993-11-23 2004-06-22 The Regents Of The University Of California Abundant extracellular product vaccines and methods for their production and use
WO1995032277A1 (en) * 1994-05-23 1995-11-30 Albert Einstein College Of Medicine Of Yeshiva University Insertional mutations in mycobacteria
US5843664A (en) * 1996-06-11 1998-12-01 Institut Pasteur Method of selection of allelic exchange mutants
US6013660A (en) * 1996-10-02 2000-01-11 The Regents Of The University Of California Externally targeted prophylactic and chemotherapeutic method and agents
US6221364B1 (en) * 1996-11-12 2001-04-24 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacteria auxotrophic for diaminopimelate
US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US6403100B1 (en) * 1997-07-10 2002-06-11 The United States Of America As Represented By The Department Of Health And Human Services Method of attenuating pathogenic mycobacteria and strains of mycobacteria so attenuated
US6387694B1 (en) * 1998-04-03 2002-05-14 Albert Einstein College Of Medicine Of Yeshiva University Mycobacterial isocitrate lyase gene and uses thereof
US7115730B1 (en) 1999-04-27 2006-10-03 Chiron Srl Immunogenic detoxified mutant E. coli LT-A-toxin
WO2001051649A2 (en) 2000-01-11 2001-07-19 The Board Of Regents Of The University Of Nebraska Identification of virulence determinants
CL2007002710A1 (es) * 2007-09-20 2008-01-04 Univ Pontificia Catolica Chile Formulacion inmunogenica que confiere proteccion contra la infeccion o patologia causada por el virus respiratorio sincicial (vrs) que comprende una cepa recombinante atenuada de mycobacterium; y uso de la formulacion inmunogenica para preparar una vacuna para prevenir, tratar o atenuar infecciones del vrs.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015873A1 (en) * 1989-06-19 1990-12-27 Whitehead Institute For Biomedical Research Vector-mediated genomic insertion and expression of dna in bcg
US5504005A (en) * 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
WO1988006626A1 (en) * 1987-03-02 1988-09-07 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
CA2045842A1 (en) * 1990-07-16 1992-01-17 William R. Jacobs Dna capable of site-specific integration into mycobacteria

Also Published As

Publication number Publication date
EP0590027A4 (de) 1994-10-19
JPH06511145A (ja) 1994-12-15
WO1992022326A1 (en) 1992-12-23
FI935566A (fi) 1993-12-10
AU1635797A (en) 1997-06-12
CA2111217A1 (en) 1992-12-23
EP0590027A1 (de) 1994-04-06
FI935566A0 (fi) 1993-12-10
EP0972839A1 (de) 2000-01-19
NO934515D0 (no) 1993-12-09
AU2189392A (en) 1993-01-12

Similar Documents

Publication Publication Date Title
NO934515L (no) Innskudd-mutasjoner i mycobakterier
Golovliov et al. A method for allelic replacement in Francisella tularensis
Prakash et al. Isolation and characterization of MMS-sensitive mutants of Saccharomyces cerevisiae
Chaveroche et al. A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans
Anderson et al. Tandem chromosomal duplications in Salmonella typhimurium: fusion of histidine genes to novel promoters
Miller Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair
Lauriano et al. Allelic exchange in Francisella tularensis using PCR products
Pelicic et al. Expression of the Bacillus subtilis sacB gene confers sucrose sensitivity on mycobacteria
AU585481B2 (en) Non-toxinogenic vibrio cholerae mutants
Prakash et al. Effects of the rad52 gene on sister chromatid recombination in Saccharomyces cerevisiae
Kusano et al. DNA double-strand break repair: genetic determinants of flanking crossing-over.
Kemper Gene order and co-transduction in the leu-ara-fol-pyrA region of the Salmonella typhimurium linkage map
Reens et al. Salmonella enterica requires lipid metabolism genes to replicate in proinflammatory macrophages and mice
DK0722503T3 (da) Suppressor-mutanter af mælkesyrebakterier og deres anvendelse som selektive markører og som indeslutningsmiddel i mælkesyrebakterier
Naito et al. Selfish restriction modification genes: resistance of a resident R/M plasmid to displacement by an incompatible plasmid mediated by host killing
Murphy et al. Transfer of the IncJ plasmid R391 to recombination deficient Escherichia coli K12: evidence that R391 behaves as a conjugal transposon
Früh et al. Construction of recombination-deficient strains of Pseudomonas aeruginosa
Heitman et al. DNA nicks inflicted by restriction endonucleases are repaired by a RecA‐and RecB‐dependent pathway in Escherichia coli
Galamba et al. Disruption of adhC reveals a large duplication in the Mycobacterium smegmatis mc2155 genome
Joseleau-Petit et al. DNA replication initiation, doubling of rate of phospholipid synthesis, and cell division in Escherichia coli
Shinners et al. Arginine and pyrimidine biosynthetic defects in Neisseria gonorrhoeae strains isolated from patients
Schwartz Suppression of a lac o mutation in Escherichia coli
Wang et al. Plasmid DNA transfer in Mycobacterium smegmatis involves novel DNA rearrangements in the recipient, which can be exploited for molecular genetic studies
Sá-Nogueira et al. Isolation of constitutive mutants for L-arabinose utilization in Bacillus subtilis
Aono et al. Genetic recombination after cell fusion of protoplasts from the facultative alkaliphile Bacillus sp. C-125