NO924978D0 - CHINOLON AND NAFTYRIDON CARBOXYLIC ACID DERIVATIVES - Google Patents
CHINOLON AND NAFTYRIDON CARBOXYLIC ACID DERIVATIVESInfo
- Publication number
- NO924978D0 NO924978D0 NO924978A NO924978A NO924978D0 NO 924978 D0 NO924978 D0 NO 924978D0 NO 924978 A NO924978 A NO 924978A NO 924978 A NO924978 A NO 924978A NO 924978 D0 NO924978 D0 NO 924978D0
- Authority
- NO
- Norway
- Prior art keywords
- naftyridon
- chinolon
- carboxylic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Fodder In General (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4200414A DE4200414A1 (en) | 1992-01-10 | 1992-01-10 | New quinoline and naphthyridinone-carboxylic acid derivs. |
DE4208792A DE4208792A1 (en) | 1992-03-19 | 1992-03-19 | New quinoline and naphthyridinone-carboxylic acid derivs. |
DE4208789A DE4208789A1 (en) | 1992-03-19 | 1992-03-19 | New quinoline and naphthyridinone-carboxylic acid derivs. |
Publications (3)
Publication Number | Publication Date |
---|---|
NO924978D0 true NO924978D0 (en) | 1992-12-22 |
NO924978L NO924978L (en) | 1993-07-12 |
NO301420B1 NO301420B1 (en) | 1997-10-27 |
Family
ID=27203290
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO924978A NO301420B1 (en) | 1992-01-10 | 1992-12-22 | Quinolone and naphthyridone carboxylic acid derivatives and their use |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0550903A1 (en) |
JP (3) | JPH05271229A (en) |
KR (1) | KR100251886B1 (en) |
CN (3) | CN1043142C (en) |
AU (1) | AU669502B2 (en) |
CA (1) | CA2086914C (en) |
CZ (1) | CZ289076B6 (en) |
FI (3) | FI104174B1 (en) |
HU (1) | HU219488B (en) |
MX (1) | MX9207604A (en) |
MY (1) | MY115416A (en) |
NO (1) | NO301420B1 (en) |
NZ (1) | NZ245640A (en) |
PL (1) | PL174853B1 (en) |
SK (3) | SK282971B6 (en) |
TW (1) | TW209865B (en) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04445A (en) | 1990-04-17 | 1992-01-06 | Fuji Photo Film Co Ltd | Processing method for silver halide color photosensitive material |
DE69131509T2 (en) | 1990-05-09 | 1999-11-25 | Fuji Photo Film Co., Ltd. | Photographic processing composition and processing method using the same |
DE4121214A1 (en) * | 1991-06-27 | 1993-01-14 | Bayer Ag | 7-AZAISOINDOLINYL CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES |
NO301165B1 (en) * | 1992-12-25 | 1997-09-22 | Daiichi Seiyaku Co | Bicyclic amine derivatives and antibacterial agents containing them |
KR0148277B1 (en) * | 1993-01-18 | 1998-11-02 | 채영복 | Novel fluoroquinolone derivatives and process for the preparation thereof |
DE4301246A1 (en) * | 1993-01-19 | 1994-07-21 | Bayer Ag | Quinolone and naphthyridonecarboxylic acid derivatives |
JP3372994B2 (en) | 1993-06-11 | 2003-02-04 | 富士写真フイルム株式会社 | Processing method of silver halide color photographic light-sensitive material |
DE4329600A1 (en) * | 1993-09-02 | 1995-03-09 | Bayer Ag | Pyrido [1,2,3-d, e] [1,3,4] benzoxadiazine derivatives |
KR950018003A (en) * | 1993-12-09 | 1995-07-22 | 스미스클라인 비참 피엘씨 | Novel quinolone derivatives and methods for their preparation |
DE4342186A1 (en) * | 1993-12-10 | 1995-06-14 | Bayer Ag | One-pot process for the production of 3-quinolonecarboxylic acid derivatives |
DE4418510A1 (en) * | 1994-05-27 | 1995-11-30 | Bayer Ag | 1,9-bridged thiazolol [3,4-a] quinoline derivatives |
WO1996040981A1 (en) * | 1995-06-07 | 1996-12-19 | Bayer Aktiengesellschaft | Testing device for determining the susceptibility of microorganisms to inhibitory agents |
DE19546249A1 (en) * | 1995-12-12 | 1997-06-19 | Bayer Ag | New crystal modification of 1-cyclopropyl-7 - ([S, S] -2,8-diazabicyclo [4,3,0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4 -oxo-3-quinoline carboxylic acid hydrochloride (CDCH), process for its preparation and pharmaceutical preparations containing it |
DE19652239A1 (en) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Use of 7- (2-oxa-5,8-diazabicyclo [4.3.0] non-8-yl) -quinolone and naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and the associated gastroduodenal diseases |
DE19735198A1 (en) * | 1997-08-14 | 1999-02-18 | Bayer Ag | Optical resolution of cis- or trans-pyrrolo:piperidine derivatives |
PL192273B1 (en) * | 1997-09-25 | 2006-09-29 | Bayer Ag | Therapeutic agent preparation of controllable active substance release |
DE19751948A1 (en) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Rapid preparation of 8-alkoxy-quinolone-carboxylic acid derivative antibacterial agent, e.g. gatifloxacin, in high purity |
DE19821039A1 (en) | 1998-05-11 | 1999-11-18 | Bayer Ag | Production of (S,S)-8-benzyl-2,8-diazabicyclo(4.3.0)nonane useful as intermediate for antibiotic moxifloxacin |
US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
AR020661A1 (en) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | A PHARMACEUTICAL COMPOSITION TOPICA OFTALMICA, OTICA OR NASAL AND THE USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT |
US6509327B1 (en) | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
HU229065B1 (en) * | 1998-11-10 | 2013-07-29 | Bayer Ip Gmbh | Pharmaceutical moxifloxacin compositions |
CN1343128B (en) | 1999-03-17 | 2010-04-21 | 第一制药株式会社 | Medicinal compositions |
DE19927412A1 (en) * | 1999-06-16 | 2000-12-21 | Bayer Ag | Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane |
DE19931115A1 (en) | 1999-07-06 | 2001-01-11 | Bayer Ag | Racemization of R, S-dioxo-benzylpyrrolopiperidine |
DE19962470A1 (en) | 1999-12-22 | 2001-07-12 | Schulz Hans Herrmann | Use of chemotherapy drugs |
DE10226923A1 (en) * | 2002-06-17 | 2003-12-24 | Bayer Ag | Process for the enantiomer enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane |
ITMI20032259A1 (en) * | 2003-11-20 | 2005-05-21 | Chemi Spa | NEW POLYMORPHOUS OF ACID 1-CYCLOPROPYL-7- (S, S-2,8-DIAZABICLO-4.3.0-NON-8-IL) -6-FLUORO-1,4-DIIDRO-8-METOSSI-4-OXO -CHINOLIN CARBOSXYL CHLORIDRATE AND METHODS FOR ITS PREPARATION |
ES2319125T3 (en) * | 2003-11-20 | 2009-05-04 | Chemi S.P.A. | POLYMORPHES OF ACID CHLORHYDRATE 1-CICLOPROPIL-7 - ((S, S) -2,8-DIAZADICICLO (4.3.0) -NON-8-IL) -6-FLUORO-1,4-DIHYDRO-8-METOXI- 4-OXO-3-CARBOXYLIN CHINOLINE AND METHODS FOR THE PREPARATION OF THE SAME. |
US7759362B2 (en) | 2004-04-21 | 2010-07-20 | Institut Of Medicinal Biotechnology Chinese Academy Of Medical Sciences | Quinolonecarboxylic acid compounds, preparation methods and pharmaceutical uses thereof |
CN1244582C (en) * | 2004-04-21 | 2006-03-08 | 中国医学科学院医药生物技术研究所 | Compound of quinolone carboxylic acid, preparation method and medicinal usage |
ES2284380B1 (en) * | 2006-03-10 | 2008-11-01 | Quimica Sintetica S.A. | PROCEDURE FOR THE PREPARATION OF MOXIFLOXACINO AND MOXIFLOXACINO CHLORHYDRATE. |
EP2032521B1 (en) | 2006-06-27 | 2009-10-28 | Sandoz AG | New method for salt preparation |
AU2007320997B2 (en) | 2006-11-13 | 2012-11-08 | Cipla Limited | Process for the synthesis of moxifloxacin hydrochloride |
WO2008059521A2 (en) * | 2006-11-14 | 2008-05-22 | Msn Laboratories Limited | Novel process for the preparation of moxifloxacin hydrochloride and a novel polymorph of moxifloxacin |
US7692015B2 (en) | 2007-01-05 | 2010-04-06 | Zheqing Wang | Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer |
WO2008102188A1 (en) | 2007-02-22 | 2008-08-28 | Tibor Nagy | Procedure to manufacture and use beer and other types liquids treated with neodimium magnet |
EP2083010A1 (en) | 2008-01-08 | 2009-07-29 | Chemo Ibérica, S.A. | Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof |
EP2154137A1 (en) | 2008-08-04 | 2010-02-17 | Chemo Ibérica, S.A. | Crystalline form of moxifloxacin base |
IT1393337B1 (en) | 2009-03-06 | 2012-04-20 | Italiana Sint Spa | SUMMARY OF (4AS, 7AS) -OTTAIDRO-1H-PIRROLO [3,4-B] PYRIDINE |
WO2010122774A1 (en) * | 2009-04-20 | 2010-10-28 | 株式会社カネカ | Processes for producing (1s,6s)- or (1r,6r)-cis-2,8-diazabicyclo[4.3.0]nonane and intermediate thereof |
IT1398952B1 (en) * | 2010-03-19 | 2013-03-28 | F S I Fabbrica Italiana Sint | PROCESS OF PREPARATION OF MOXIFLOXACINE AND ITS SALTS |
CN101941969B (en) * | 2010-09-30 | 2012-05-23 | 江苏正大丰海制药有限公司 | Preparation method of moxifloxacin hydrochloride |
CN102675307A (en) * | 2011-03-17 | 2012-09-19 | 苏州中科天马肽工程中心有限公司 | Method for preparing chiral compound 8-phenethyl-2,8-diazabicyclo[4.3.0]nonane |
CN102675308A (en) * | 2011-03-17 | 2012-09-19 | 苏州中科天马肽工程中心有限公司 | Method for preparing 8-benzyl-2,8-diazabicyclo(4.3.0) nonane |
ITTO20110705A1 (en) | 2011-07-29 | 2013-01-30 | Italiana Sint Spa | PROCEDURE FOR THE PREPARATION OF MOXIFLOXACINE CHLORIDRATE AND RELATED INTERMEDIATES |
CN102964346B (en) * | 2011-09-01 | 2015-04-22 | 中国中化股份有限公司 | Preparation method of (S, S)-octahydro-6H-pyrrolo[3, 4-b]pyridine |
CN103044418B (en) * | 2011-10-14 | 2015-02-04 | 上海朴颐化学科技有限公司 | Asymmetric synthesis method, relevant raw materials and preparation method of (S,S)-2,8-diazabicyclo[4,3,0] nonane |
CN102408427B (en) * | 2011-10-22 | 2012-12-12 | 浙江普洛康裕制药有限公司 | Preparation method for moxifloxacin intermediate (1S, 6R)-8-benzyl-7, 9-dioxy-2, 8-diazabicyclo [4.3.0] nonane |
BRPI1106900A2 (en) | 2011-12-26 | 2013-11-05 | Ems Sa | SOLID PHARMACEUTICAL COMPOSITION UNDERSTANDING ANTIBOTH FAMILY OF QUINOLONES AND THE PROCESS OF OBTAINING THEM |
FR2992218B1 (en) | 2012-06-22 | 2015-01-23 | Rivopharm Sa | PHARMACEUTICAL COMPOSITION OF MOXIFLOXACIN HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME |
US9388178B2 (en) | 2012-12-04 | 2016-07-12 | Mankind Research Centre | Process for the preparation of moxifloxacin hydrochloride |
CN103012452B (en) * | 2012-12-25 | 2015-12-02 | 浙江新和成股份有限公司 | The preparation method of a kind of Moxifloxacin and hydrochloride thereof |
UA106556C2 (en) | 2013-05-13 | 2014-09-10 | Наталья Николаевна Деркач | Method of obtaining (1-cyclopropyl -6- fluoro-1,4-dihydro methoxy -8 -7 - [(4as, 7as) - oktahydro -6n- pyrrolo [3,4-pyridine bsch - 6- yl] -4-oxo-3-hinolinkarbonovoyi acid |
CN103724262B (en) * | 2013-12-10 | 2016-05-18 | 广东省第二人民医院 | A kind of fluoquinolone silver compound and its production and use |
CN104860944A (en) * | 2015-06-09 | 2015-08-26 | 内蒙古东北六药集团有限公司 | Production method of moxifloxacin hydrochloride |
CN108872413B (en) * | 2018-04-27 | 2021-06-08 | 山东齐都药业有限公司 | Method for detecting enantiomer content in (S, S) -2, 8-diazabicyclo [4,3,0] nonane |
CN110627768B (en) * | 2018-06-22 | 2021-11-09 | 扬子江药业集团有限公司 | Preparation method of moxifloxacin degradation impurity J |
CN110183445B (en) * | 2019-06-28 | 2021-08-24 | 昆明学院 | Synthetic method of moxifloxacin and derivatives thereof |
RU2713932C1 (en) * | 2019-10-31 | 2020-02-11 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Fluoroquinolone compounds based on pyridoxine derivatives, having antibacterial properties |
CN112939849B (en) * | 2019-12-11 | 2022-05-03 | 浙江新和成股份有限公司 | (S, S) -2, 8-diazabicyclo [4.3.0] nonane intermediate and preparation method and application thereof |
CN110981874A (en) * | 2020-03-05 | 2020-04-10 | 北京四环生物制药有限公司 | Preparation method of moxifloxacin hydrochloride |
CN112409352B (en) * | 2020-11-20 | 2022-05-24 | 华南理工大学 | Moxifloxacin drug derivatives and preparation method and application thereof |
CN112574197B (en) * | 2020-12-07 | 2021-12-31 | 泰安汉威集团有限公司 | Chiral purification method of compound C |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0754229B2 (en) * | 1987-09-28 | 1995-06-07 | 松下冷機株式会社 | refrigerator |
DE3906365A1 (en) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM |
AU5123690A (en) * | 1989-03-13 | 1990-09-13 | Bristol-Myers Squibb Company | 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents |
DE3910663A1 (en) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-ALKYLCHINOLON CARBONIC ACIDS |
JPH03188080A (en) * | 1989-12-15 | 1991-08-16 | Banyu Pharmaceut Co Ltd | Pyridonecarboxylic acid derivative |
-
1992
- 1992-10-12 TW TW081108103A patent/TW209865B/zh not_active IP Right Cessation
- 1992-12-22 NO NO924978A patent/NO301420B1/en not_active IP Right Cessation
- 1992-12-28 EP EP92122058A patent/EP0550903A1/en not_active Withdrawn
- 1992-12-29 CZ CS19923966A patent/CZ289076B6/en not_active IP Right Cessation
- 1992-12-29 SK SK3966-92A patent/SK282971B6/en not_active IP Right Cessation
- 1992-12-29 SK SK223-2000A patent/SK285223B6/en not_active IP Right Cessation
- 1992-12-29 SK SK221-2000A patent/SK285155B6/en not_active IP Right Cessation
- 1992-12-29 MX MX9207604A patent/MX9207604A/en unknown
-
1993
- 1993-01-05 JP JP5015917A patent/JPH05271229A/en active Pending
- 1993-01-06 AU AU31054/93A patent/AU669502B2/en not_active Expired
- 1993-01-07 FI FI930049A patent/FI104174B1/en not_active IP Right Cessation
- 1993-01-07 CA CA002086914A patent/CA2086914C/en not_active Expired - Lifetime
- 1993-01-08 NZ NZ245640A patent/NZ245640A/en not_active IP Right Cessation
- 1993-01-08 HU HU9300034A patent/HU219488B/en unknown
- 1993-01-08 PL PL93297338A patent/PL174853B1/en unknown
- 1993-01-09 KR KR1019930000227A patent/KR100251886B1/en not_active IP Right Cessation
- 1993-01-09 CN CN93100215A patent/CN1043142C/en not_active Expired - Lifetime
- 1993-01-10 MY MYPI93000039A patent/MY115416A/en unknown
-
1997
- 1997-12-20 CN CN97108773A patent/CN1061351C/en not_active Expired - Lifetime
-
1998
- 1998-05-29 CN CN98109504A patent/CN1075499C/en not_active Expired - Lifetime
-
1999
- 1999-02-03 FI FI990207A patent/FI110943B/en not_active IP Right Cessation
-
2002
- 2002-01-11 FI FI20020059A patent/FI113771B/en not_active IP Right Cessation
- 2002-05-20 JP JP2002144273A patent/JP2003026574A/en active Pending
- 2002-05-20 JP JP2002144576A patent/JP4111431B2/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |