NO924723D0 - Farmakologisk anvendelse av visse cystinderivater - Google Patents
Farmakologisk anvendelse av visse cystinderivaterInfo
- Publication number
- NO924723D0 NO924723D0 NO924723A NO924723A NO924723D0 NO 924723 D0 NO924723 D0 NO 924723D0 NO 924723 A NO924723 A NO 924723A NO 924723 A NO924723 A NO 924723A NO 924723 D0 NO924723 D0 NO 924723D0
- Authority
- NO
- Norway
- Prior art keywords
- cystin
- derivatives
- certain
- pharmacological use
- pharmacological
- Prior art date
Links
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical class [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 title abstract 2
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9002067A SE9002067D0 (sv) | 1990-06-08 | 1990-06-08 | The pharmacological use of certain cystine derivatives |
SE9002275A SE9002275D0 (sv) | 1990-06-28 | 1990-06-28 | Novel 3,3'-dithiobis(propionic acids) |
PCT/SE1991/000388 WO1991018594A1 (en) | 1990-06-08 | 1991-06-03 | The pharmacological use of certain cystine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
NO924723L NO924723L (no) | 1992-12-07 |
NO924723D0 true NO924723D0 (no) | 1992-12-07 |
Family
ID=26660796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO924723A NO924723D0 (no) | 1990-06-08 | 1992-12-07 | Farmakologisk anvendelse av visse cystinderivater |
Country Status (20)
Country | Link |
---|---|
US (2) | US5441976A (no) |
EP (1) | EP0532595B1 (no) |
JP (1) | JP3204320B2 (no) |
KR (1) | KR100236253B1 (no) |
AT (1) | ATE144705T1 (no) |
AU (1) | AU652946B2 (no) |
CA (1) | CA2083274C (no) |
DE (1) | DE69122961T2 (no) |
DK (1) | DK0532595T3 (no) |
HK (1) | HK62597A (no) |
HU (1) | HU215920B (no) |
IE (1) | IE80754B1 (no) |
IL (1) | IL98310A (no) |
LV (2) | LV10186B (no) |
NO (1) | NO924723D0 (no) |
NZ (1) | NZ247658A (no) |
PT (1) | PT97905B (no) |
RU (1) | RU2119793C1 (no) |
SG (1) | SG49736A1 (no) |
WO (1) | WO1991018594A1 (no) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9018994D0 (en) * | 1990-08-31 | 1990-10-17 | Secr Defence | Toxic agent protective compounds |
US5889050A (en) * | 1991-06-21 | 1999-03-30 | Astra Aktiebolag | 3,3'-dithiobis (propionic acids) and esters thereof |
SE9103572D0 (sv) * | 1991-11-29 | 1991-11-29 | Astra Ab | Organic salts of n,n'-diacetyl cystine |
JP2947044B2 (ja) * | 1993-01-27 | 1999-09-13 | 味の素株式会社 | 免疫不全症候群治療の補助療法剤 |
DE4329857C2 (de) * | 1993-09-03 | 1995-08-24 | Deutsches Krebsforsch | Verbindung zur Stärkung des Immunsystems und von Immunreaktionen |
SE9500897D0 (sv) * | 1995-03-14 | 1995-03-14 | Astra Ab | The pharmacological use of certain cystine derivatives |
SE9501067D0 (sv) * | 1995-03-24 | 1995-03-24 | Astra Ab | New peptides |
SE9602262D0 (sv) * | 1996-06-06 | 1996-06-06 | Astra Ab | New use of derivatives of cystine |
US6197749B1 (en) | 1997-10-29 | 2001-03-06 | Ajinomoto Co., Inc. | Method of suppressing immune responses by reducing intracellular content of glutathione in macrophages and monocytes |
US20030203006A1 (en) * | 1997-10-29 | 2003-10-30 | Ajinomoto Co. Inc. | Immunomodulator |
KR20010075000A (ko) * | 1998-10-09 | 2001-08-09 | 에가시라 구니오 | 시스테인 유도체 |
EP1004302A3 (en) * | 1998-10-29 | 2003-06-04 | Ajinomoto Co., Inc. | Immunomodulator |
SE9900438D0 (sv) * | 1999-02-10 | 1999-02-10 | Astra Ab | The pharmacological use of certian cystine derivatives |
JP3988014B2 (ja) * | 2000-02-02 | 2007-10-10 | 味の素株式会社 | ウイルス感染症予防剤 |
ATE517607T1 (de) | 2000-11-30 | 2011-08-15 | Vectura Ltd | Verfahren zur herstellung von partikeln zur verwendung in einer pharmazeutischen zusammensetzung |
SE518784C2 (sv) * | 2000-12-27 | 2002-11-19 | Nactilus Ab | "N-Acetyl-L-cystein med kompositioner för behandling av neoplasier" |
US8530509B2 (en) | 2003-06-20 | 2013-09-10 | Siga Technologies, Inc. | Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases |
DE102004043055B4 (de) | 2004-09-06 | 2009-04-02 | Siemens Ag | Führungsvorrichtung zur Führung eines bewegbaren Maschinenelementes einer Maschine |
EP2068903A4 (en) * | 2006-10-03 | 2010-11-03 | Galleon Pharmaceuticals Inc | S-NITROSOTHIOL COMPOUNDS AND RELATED DERIVATIVES |
JP2010535705A (ja) * | 2007-04-23 | 2010-11-25 | シガ テクノロジーズ,インコーポレーテッド | オルソポックスウイルス感染及び関連疾患の治療及び予防のための化学物質、組成物、及び方法 |
US7829709B1 (en) | 2007-08-10 | 2010-11-09 | Marquette University | Cysteine prodrugs to treat schizophrenia and drug addiction |
US8173809B2 (en) | 2008-02-07 | 2012-05-08 | Marquette University | Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings |
CN106232577B (zh) | 2014-04-25 | 2019-02-22 | 味之素株式会社 | 免疫刺激剂 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR8205M (no) * | 1968-12-20 | 1970-09-14 | ||
US3878305A (en) * | 1972-05-25 | 1975-04-15 | Procter & Gamble | Fortification of foodstuffs with n-acyl derivatives of sulphur-containing l-amino acids |
US3952115A (en) * | 1975-04-02 | 1976-04-20 | The Procter & Gamble Company | Fortification of foodstuffs with N-acyl derivatives of sulfur-containing L-amino acid esters |
GB2097256B (en) * | 1981-04-02 | 1985-05-30 | Morelle Jean V | Compositions containing n-butyryl alphaaminoacids |
FR2503151A1 (fr) * | 1981-04-02 | 1982-10-08 | Morelle Jean | Butyryminoacides soufres. mode de preparation. emploi comme element keratogenique chez l'homme et l'animal et comme agent de fertilisation chez les vegetaux |
US4827016A (en) * | 1985-09-16 | 1989-05-02 | Morgan Lee R | Method and compounds for reducing dermal inflammations |
US4708965A (en) * | 1985-09-16 | 1987-11-24 | Morgan Lee R | Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives |
US4724239A (en) * | 1985-09-16 | 1988-02-09 | Morgan Lee R | Method of treating chemical ulcers with N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine |
IT1249650B (it) * | 1991-05-29 | 1995-03-09 | Poli Ind Chimica Spa | N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico |
-
1991
- 1991-05-30 IL IL9831091A patent/IL98310A/en not_active IP Right Cessation
- 1991-06-03 CA CA002083274A patent/CA2083274C/en not_active Expired - Fee Related
- 1991-06-03 KR KR1019920703125A patent/KR100236253B1/ko not_active IP Right Cessation
- 1991-06-03 WO PCT/SE1991/000388 patent/WO1991018594A1/en active IP Right Grant
- 1991-06-03 AT AT91910813T patent/ATE144705T1/de not_active IP Right Cessation
- 1991-06-03 DK DK91910813.4T patent/DK0532595T3/da active
- 1991-06-03 RU RU92016463A patent/RU2119793C1/ru not_active IP Right Cessation
- 1991-06-03 JP JP51096391A patent/JP3204320B2/ja not_active Expired - Fee Related
- 1991-06-03 HU HU9203871A patent/HU215920B/hu not_active IP Right Cessation
- 1991-06-03 DE DE69122961T patent/DE69122961T2/de not_active Expired - Fee Related
- 1991-06-03 AU AU80941/91A patent/AU652946B2/en not_active Ceased
- 1991-06-03 EP EP91910813A patent/EP0532595B1/en not_active Expired - Lifetime
- 1991-06-03 SG SG1996004501A patent/SG49736A1/en unknown
- 1991-06-07 IE IE194591A patent/IE80754B1/en not_active IP Right Cessation
- 1991-06-07 PT PT97905A patent/PT97905B/pt not_active IP Right Cessation
-
1992
- 1992-12-04 US US07/949,648 patent/US5441976A/en not_active Expired - Lifetime
- 1992-12-07 NO NO924723A patent/NO924723D0/no unknown
-
1993
- 1993-05-20 NZ NZ247658A patent/NZ247658A/en unknown
- 1993-08-06 LV LVP-93-1017A patent/LV10186B/en unknown
-
1995
- 1995-06-01 US US08/457,004 patent/US5780508A/en not_active Expired - Fee Related
-
1997
- 1997-05-08 HK HK62597A patent/HK62597A/xx not_active IP Right Cessation
- 1997-10-30 LV LVP-97-219A patent/LV11985B/en unknown
Also Published As
Publication number | Publication date |
---|---|
NZ247658A (en) | 2000-07-28 |
US5441976A (en) | 1995-08-15 |
CA2083274C (en) | 2002-05-28 |
EP0532595A1 (en) | 1993-03-24 |
AU8094191A (en) | 1991-12-31 |
RU2119793C1 (ru) | 1998-10-10 |
IE80754B1 (en) | 1999-01-13 |
PT97905A (pt) | 1992-03-31 |
WO1991018594A1 (en) | 1991-12-12 |
LV10186A (lv) | 1994-10-20 |
CA2083274A1 (en) | 1991-12-09 |
AU652946B2 (en) | 1994-09-15 |
IL98310A (en) | 1996-08-04 |
DE69122961T2 (de) | 1997-03-13 |
LV11985B (en) | 1998-06-20 |
DK0532595T3 (da) | 1997-04-07 |
PT97905B (pt) | 1998-10-30 |
NO924723L (no) | 1992-12-07 |
HU215920B (hu) | 1999-03-29 |
US5780508A (en) | 1998-07-14 |
HU9203871D0 (en) | 1993-03-29 |
IE911945A1 (en) | 1991-12-18 |
LV10186B (en) | 1995-08-20 |
SG49736A1 (en) | 1998-06-15 |
HK62597A (en) | 1997-05-16 |
KR100236253B1 (ko) | 1999-12-15 |
JPH05507705A (ja) | 1993-11-04 |
LV11985A (lv) | 1998-03-20 |
HUT70055A (en) | 1995-09-28 |
IL98310A0 (en) | 1992-06-21 |
DE69122961D1 (de) | 1996-12-05 |
JP3204320B2 (ja) | 2001-09-04 |
EP0532595B1 (en) | 1996-10-30 |
ATE144705T1 (de) | 1996-11-15 |
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