NO923875L - Metode og preparat for behandling av trombose - Google Patents

Metode og preparat for behandling av trombose

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Publication number
NO923875L
NO923875L NO92923875A NO923875A NO923875L NO 923875 L NO923875 L NO 923875L NO 92923875 A NO92923875 A NO 92923875A NO 923875 A NO923875 A NO 923875A NO 923875 L NO923875 L NO 923875L
Authority
NO
Norway
Prior art keywords
peptides
contain
rgd
adjacent
provides
Prior art date
Application number
NO92923875A
Other languages
English (en)
Other versions
NO923875D0 (no
Inventor
Michael D Pierschbacher
David S Lukeman
Soan Cheng
William S Craig
Juerg F Tschopp
Original Assignee
Jolla Cancer Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1991/002356 external-priority patent/WO1991015515A1/en
Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found
Publication of NO923875D0 publication Critical patent/NO923875D0/no
Publication of NO923875L publication Critical patent/NO923875L/no

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Oppfinnelsen tilveiebringer syk- liske peptider som inhiberer blodplate- aggregering uten å forårsake forlenget blødningstid. Oppfinnelsen tilveie- bringer RGD- eller KGD-holdige peptider som er syklisert og inneholder hydro- fobe grupper tilstøtende karboksyenden av RGD-sekvensen. Peptider av denne art er også tilveiebrakt som inneholder i tillegg til den hydrofobe gruppe, en tilstøtende, positivt ladet gruppe. Slike peptider har høy affinitet for reseptoren Ilb/IIIa og en lav affinitetfor fibronektin- og vitronektin-resep- torene. Slike peptider kan adminis- treres i en egnet fysiologisk aksep- tabel bærer for terapeutisk å behandle trombose.
NO92923875A 1990-04-06 1992-10-05 Metode og preparat for behandling av trombose NO923875L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50644490A 1990-04-06 1990-04-06
PCT/US1991/002356 WO1991015515A1 (en) 1990-04-06 1991-04-05 Method and composition for treating thrombosis

Publications (2)

Publication Number Publication Date
NO923875D0 NO923875D0 (no) 1992-10-05
NO923875L true NO923875L (no) 1992-12-04

Family

ID=26783052

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923875A NO923875L (no) 1990-04-06 1992-10-05 Metode og preparat for behandling av trombose

Country Status (1)

Country Link
NO (1) NO923875L (no)

Also Published As

Publication number Publication date
NO923875D0 (no) 1992-10-05

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