NO922608L - NEW CEPHALOSPOR RELATIONS AND PROCEDURES FOR THEIR PREPARATION - Google Patents

NEW CEPHALOSPOR RELATIONS AND PROCEDURES FOR THEIR PREPARATION

Info

Publication number
NO922608L
NO922608L NO92922608A NO922608A NO922608L NO 922608 L NO922608 L NO 922608L NO 92922608 A NO92922608 A NO 92922608A NO 922608 A NO922608 A NO 922608A NO 922608 L NO922608 L NO 922608L
Authority
NO
Norway
Prior art keywords
alkyl
preparation
compounds
group
cephalospor
Prior art date
Application number
NO92922608A
Other languages
Norwegian (no)
Other versions
NO922608D0 (en
Inventor
Yong Zu Kim
Hun Seung Oh
Jae Hong Yeo
Jong Chan Lim
Won Sup Kim
Chan Sik Bang
Hyeon Joo Yim
Original Assignee
Lucky Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lucky Ltd filed Critical Lucky Ltd
Publication of NO922608D0 publication Critical patent/NO922608D0/en
Publication of NO922608L publication Critical patent/NO922608L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Den foreliggende oppfinnelse angår nye cefalosporinforbindelser med formel (I), farmasøytisk, akseptable, ikke-toksiske salter derav, og fysiologisk, hydrolyserbare estere og oppløsninger derav, som har kraftig og bred ant ibakteri el l virkning. I formelen (I) er R , C.j_. alkyl-, C3_. alkenyl-, C, , alkynyl-grupper, eller -C(R ) (R )CO?H, hvori R og R er de samme eller forskjellige, og hver er et hydrogenatom eller en C... alkylgruppe, eller Ra og R danner en C, , cykloalkylgruppe med karbonatomet som de er bundet 2 J- / til; R er en C. . alkyl-, C, . alkenyl- eller C, . cykloalkyl- gruppe, en substituert eller usubstituert aminogruppe, eller en substituert eller usubstituert fenyl-gruppe; R er hydrogen eller en C-, alkylgruppe; og Q er N eller CH. Oppfinnelsen angår videre en fremgangsmåte for fremstilling av nevnte forbindelser og av farmasøytiske blandinger som inneholder nevnte forbindelser.The present invention relates to novel cephalosporin compounds of formula (I), pharmaceutically acceptable, non-toxic salts thereof, and physiologically, hydrolysable esters and solutions thereof, which have potent and broad antibacterial or effect properties. In formula (I), R, C alkyl, C3-. alkenyl, C 1, alkynyl groups, or -C (R) (R) CO 2 H, wherein R and R are the same or different and each is a hydrogen atom or a C 1 forms a C1-8 cycloalkyl group having the carbon atom to which they are attached 2 J- / to; R is a C. alkyl, C,. alkenyl or C,. cycloalkyl group, a substituted or unsubstituted amino group, or a substituted or unsubstituted phenyl group; R is hydrogen or a C1-6 alkyl group; and Q is N or CH. The invention further relates to a process for the preparation of said compounds and of pharmaceutical compositions containing said compounds.

NO92922608A 1990-11-09 1992-07-01 NEW CEPHALOSPOR RELATIONS AND PROCEDURES FOR THEIR PREPARATION NO922608L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002072883A CA2072883A1 (en) 1990-11-09 1990-11-09 Cephalosporin compounds and processes for preparation thereof
PCT/KR1990/000018 WO1992008721A1 (en) 1990-11-09 1990-11-09 Novel cephalosporin compounds and processes for preparation thereof

Publications (2)

Publication Number Publication Date
NO922608D0 NO922608D0 (en) 1992-07-01
NO922608L true NO922608L (en) 1992-09-01

Family

ID=25675289

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92922608A NO922608L (en) 1990-11-09 1992-07-01 NEW CEPHALOSPOR RELATIONS AND PROCEDURES FOR THEIR PREPARATION

Country Status (5)

Country Link
AU (1) AU656886B2 (en)
CA (1) CA2072883A1 (en)
FI (1) FI923156A (en)
NO (1) NO922608L (en)
WO (1) WO1992008721A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR930007264B1 (en) * 1990-08-17 1993-08-04 주식회사 럭키 Cephalosporin compounds and its process
KR970010069B1 (en) * 1992-08-24 1997-06-20 주식회사 럭키 Cephalosporn derivatives
KR970005896B1 (en) * 1993-07-23 1997-04-21 주식회사 엘지화학 Cephalsoporins derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR231986A1 (en) * 1978-05-26 1985-04-30 Glaxo Group Ltd PROCEDURE FOR PREPARING CEPHALOSPORIN ANTIBIOTICS
DE3006888A1 (en) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
CA2005787A1 (en) * 1988-12-29 1990-06-29 Masao Wada Cephalosporin compounds
KR930007264B1 (en) * 1990-08-17 1993-08-04 주식회사 럭키 Cephalosporin compounds and its process

Also Published As

Publication number Publication date
FI923156A0 (en) 1992-07-08
CA2072883A1 (en) 1992-05-10
AU656886B2 (en) 1995-02-23
WO1992008721A1 (en) 1992-05-29
AU6631590A (en) 1992-06-11
FI923156A (en) 1992-07-08
NO922608D0 (en) 1992-07-01

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