NO922202D0 - NEW PROTEINS WITH ONCOSTATIN M ACTIVITY AND PROCEDURE FOR THE PREPARATION OF THESE - Google Patents

NEW PROTEINS WITH ONCOSTATIN M ACTIVITY AND PROCEDURE FOR THE PREPARATION OF THESE

Info

Publication number
NO922202D0
NO922202D0 NO1992922202A NO922202A NO922202D0 NO 922202 D0 NO922202 D0 NO 922202D0 NO 1992922202 A NO1992922202 A NO 1992922202A NO 922202 A NO922202 A NO 922202A NO 922202 D0 NO922202 D0 NO 922202D0
Authority
NO
Norway
Prior art keywords
oncostatin
mutants
activity
procedure
preparation
Prior art date
Application number
NO1992922202A
Other languages
Norwegian (no)
Other versions
NO922202L (en
NO301769B1 (en
Inventor
Peter S Linsley
Jeffrey C Kallestad
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of NO922202L publication Critical patent/NO922202L/en
Publication of NO922202D0 publication Critical patent/NO922202D0/en
Publication of NO301769B1 publication Critical patent/NO301769B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

The present invention is directed to biologically mutant forms of the cell growth regulatory factor Oncostatin M. The Oncostatin M mutants of the invention comprise deletion, substitution and insertion mutants and may be prepared using recombinant DNA, in vitro mutagenesis and heterologous expression techniques. Oncostatin M mutants may be useful in eliciting Oncostatin M biological responses and, as such, may find a variety of therapeutic uses including but not limited to the treatment of neoplasias.
NO922202A 1989-12-08 1992-06-04 Method of Preparation of Oncostatin M Mutant NO301769B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44775989A 1989-12-08 1989-12-08
US62386790A 1990-12-03 1990-12-03
PCT/US1990/007227 WO1991009057A1 (en) 1989-12-08 1990-12-07 Novel proteins with oncostatin m activity and process for their preparation

Publications (3)

Publication Number Publication Date
NO922202L NO922202L (en) 1992-06-04
NO922202D0 true NO922202D0 (en) 1992-06-04
NO301769B1 NO301769B1 (en) 1997-12-08

Family

ID=27035080

Family Applications (1)

Application Number Title Priority Date Filing Date
NO922202A NO301769B1 (en) 1989-12-08 1992-06-04 Method of Preparation of Oncostatin M Mutant

Country Status (17)

Country Link
EP (1) EP0504291B1 (en)
JP (1) JPH05504134A (en)
KR (1) KR920703636A (en)
CN (1) CN1055389A (en)
AT (1) ATE168117T1 (en)
AU (1) AU651330B2 (en)
CA (1) CA2070171A1 (en)
DE (1) DE69032471T2 (en)
DK (1) DK0504291T3 (en)
ES (1) ES2120958T3 (en)
FI (1) FI104424B (en)
GR (1) GR3027654T3 (en)
IL (1) IL96593A0 (en)
NO (1) NO301769B1 (en)
NZ (1) NZ236382A (en)
PT (1) PT96134B (en)
WO (1) WO1991009057A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783672A (en) * 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M
CA2178256A1 (en) * 1995-06-06 1996-12-07 Christopher H. Clegg Oncostatin m induced hematopoiesis
GB9806530D0 (en) 1998-03-26 1998-05-27 Glaxo Group Ltd Inflammatory mediator
US20120308517A1 (en) 2010-02-09 2012-12-06 Digna Biotech, S.L. Compositions for the treatment of infectious and tumoural diseases

Also Published As

Publication number Publication date
KR920703636A (en) 1992-12-18
ES2120958T3 (en) 1998-11-16
EP0504291A1 (en) 1992-09-23
FI922612A (en) 1992-06-05
FI922612A0 (en) 1992-06-05
AU7036191A (en) 1991-07-18
NZ236382A (en) 1992-08-26
PT96134A (en) 1991-09-30
FI104424B (en) 2000-01-31
CA2070171A1 (en) 1991-06-09
NO922202L (en) 1992-06-04
EP0504291A4 (en) 1992-10-28
AU651330B2 (en) 1994-07-21
EP0504291B1 (en) 1998-07-08
GR3027654T3 (en) 1998-11-30
DE69032471D1 (en) 1998-08-13
NO301769B1 (en) 1997-12-08
CN1055389A (en) 1991-10-16
IL96593A0 (en) 1991-09-16
ATE168117T1 (en) 1998-07-15
WO1991009057A1 (en) 1991-06-27
DK0504291T3 (en) 1998-11-30
DE69032471T2 (en) 1999-03-04
PT96134B (en) 1998-04-30
JPH05504134A (en) 1993-07-01

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