NO922008L - Celleaktiverende preparat og anvendelse derav - Google Patents
Celleaktiverende preparat og anvendelse deravInfo
- Publication number
- NO922008L NO922008L NO92922008A NO922008A NO922008L NO 922008 L NO922008 L NO 922008L NO 92922008 A NO92922008 A NO 92922008A NO 922008 A NO922008 A NO 922008A NO 922008 L NO922008 L NO 922008L
- Authority
- NO
- Norway
- Prior art keywords
- cytokines
- lif
- alone
- combination
- satellite cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Medicinal Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Control Of Indicators Other Than Cathode Ray Tubes (AREA)
- Devices For Indicating Variable Information By Combining Individual Elements (AREA)
- Control Of El Displays (AREA)
Abstract
Den foreliggende oppfinnelse vedrører anvendelse av leukemi- inhiberende faktor (LIF), alene eller i kombinasjon med andre cytokiner som interleukin-6 (IL-6) og/eller transformerende vekstfaktor a (TGFa) og/eller fibroblast vekstfaktor (FGF), for å stimulere formeringen og/eller differensieringen av mammale satellittceller. Oppfinnelsen omhandler også en fremgangsmåte omfattende myoblastoverføringsterapi hvorved LIF, alene eller i kombinasjon med andre cytokiner. anvendes for å formere og/eller differensiere mammale satellittceller i myoblastet. Oppfinnelsen er også rettet på en celle- aktiverende blanding og et farmasøytisk preparat omfattende LIF alene eller i kombinasjon med andre cytokiner for å fremme formering og/eller differensiering av mammale satellittceller in vitro henholdsvis in vivo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ755289 | 1989-11-24 | ||
PCT/AU1990/000556 WO1991007992A1 (en) | 1989-11-24 | 1990-11-20 | Proliferative action of leukaemia inhibitory factor on satellite cells |
Publications (2)
Publication Number | Publication Date |
---|---|
NO922008D0 NO922008D0 (no) | 1992-05-21 |
NO922008L true NO922008L (no) | 1992-07-20 |
Family
ID=3774381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO92922008A NO922008L (no) | 1989-11-24 | 1992-05-21 | Celleaktiverende preparat og anvendelse derav |
Country Status (10)
Country | Link |
---|---|
US (1) | US5435999A (no) |
EP (1) | EP0502081B1 (no) |
JP (2) | JP3040815B2 (no) |
AT (1) | ATE138267T1 (no) |
AU (1) | AU624284B2 (no) |
CA (1) | CA2045630A1 (no) |
DE (1) | DE69027123T2 (no) |
HK (1) | HK1003475A1 (no) |
NO (1) | NO922008L (no) |
WO (1) | WO1991007992A1 (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571508A (en) * | 1989-12-18 | 1996-11-05 | Amrad Corporation Limited | Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor |
DE69119759T2 (de) * | 1990-03-20 | 1997-01-16 | Amrad Corp Ltd | Verfahren zur steuerung der neuronentwicklung und des neuronunterhalts |
ATE199498T1 (de) * | 1991-12-24 | 2001-03-15 | Amrad Corp Ltd | Verwendung von leukämieinhibierendem faktor (lif) zur behandlung von tumoren und sarkomen |
WO1994021272A1 (en) * | 1993-03-17 | 1994-09-29 | Amrad Corporation Limited | A method for treating microbial infection in an animal by administering a composition comprising lif and a cytokine |
US20020164313A1 (en) * | 1995-03-16 | 2002-11-07 | Tremblay Jacques P. | Compositions comprising preconditioned myoblasts having enhanced fusion properties |
US5833978A (en) * | 1995-03-16 | 1998-11-10 | Universite Laval | Method of in vitro preconditioning healthy donor's myoblasts before transplantation thereof in compatible patients suffering of recessive myopathies like muscular dystrophy, for improving transplantation success |
GB2301114A (en) * | 1995-05-24 | 1996-11-27 | Bradley Michael John Stringer | Method for controlling differentiation of precursor cells |
WO1996039035A1 (en) * | 1995-06-06 | 1996-12-12 | Case Western Reserve University | Myogenic differentiation of human mesenchymal stem cells |
EP0946713B1 (en) * | 1996-10-18 | 2007-03-07 | Universite Laval | Method for in vitro preconditioning of myoblasts before transplantation |
US20010041342A1 (en) * | 1998-04-01 | 2001-11-15 | The General Hospital Corporation, A Massachusetts Corporation | Molecular marker for muscle stem cells |
US6866842B1 (en) | 1998-05-01 | 2005-03-15 | University Of Pittsburgh | Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction |
US7115417B1 (en) | 1998-05-01 | 2006-10-03 | Chancellor Michael B | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
AU5159901A (en) | 2000-04-14 | 2001-10-30 | Univ Pittsburgh | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof |
WO2002067867A2 (en) | 2001-02-23 | 2002-09-06 | The University Of Pittsburgh | Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair |
US7115399B2 (en) * | 2001-07-31 | 2006-10-03 | Allergan, Inc. | Pinna reflex assay |
US7627373B2 (en) | 2002-11-30 | 2009-12-01 | Cardiac Pacemakers, Inc. | Method and apparatus for cell and electrical therapy of living tissue |
CN1812800B (zh) | 2003-04-25 | 2013-01-16 | 匹兹堡大学 | 用于促进和增强神经修复和再生的肌肉来源的细胞(mdc) |
US7840263B2 (en) * | 2004-02-27 | 2010-11-23 | Cardiac Pacemakers, Inc. | Method and apparatus for device controlled gene expression |
US7764995B2 (en) | 2004-06-07 | 2010-07-27 | Cardiac Pacemakers, Inc. | Method and apparatus to modulate cellular regeneration post myocardial infarct |
US7828711B2 (en) * | 2004-08-16 | 2010-11-09 | Cardiac Pacemakers, Inc. | Method and apparatus for modulating cellular growth and regeneration using ventricular assist device |
US8060219B2 (en) | 2004-12-20 | 2011-11-15 | Cardiac Pacemakers, Inc. | Epicardial patch including isolated extracellular matrix with pacing electrodes |
US7981065B2 (en) | 2004-12-20 | 2011-07-19 | Cardiac Pacemakers, Inc. | Lead electrode incorporating extracellular matrix |
GB2433122B (en) | 2005-12-10 | 2008-07-23 | Endet Ltd | Gas sampling probe |
CA2674795C (en) | 2007-01-11 | 2016-08-23 | University Of Pittsburgh | Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same |
US9199003B2 (en) | 2008-08-18 | 2015-12-01 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof |
US9139814B2 (en) * | 2008-09-22 | 2015-09-22 | Universite Laval | Culture medium for myoblasts, precursors thereof and derivatives thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT87133B (pt) * | 1987-04-02 | 1992-07-31 | Amrad Corp Ltd | Metodo de purificacao do factor inibidor da leucemia (lif) e de composicoes farmaceuticas contendo polipeptidos com actividade do lif |
AU609128B2 (en) * | 1987-04-02 | 1991-04-26 | Amrad Operations Pty. Limited | Leukaemia-inhibitory factor |
DE68928914T2 (de) * | 1988-08-04 | 1999-09-09 | Amrad Corp. Ltd. | (in vitro)-vermehrung von embryonalen stammzellen unter verwendung von leukämie-inhibitionsfaktor (lif) |
WO1990002183A1 (en) * | 1988-08-18 | 1990-03-08 | Genetics Institute, Inc. | Production of a novel lymphokine exhibiting differentiation inhibitory activity |
-
1990
- 1990-11-20 DE DE69027123T patent/DE69027123T2/de not_active Expired - Fee Related
- 1990-11-20 AT AT91900131T patent/ATE138267T1/de not_active IP Right Cessation
- 1990-11-20 CA CA002045630A patent/CA2045630A1/en not_active Abandoned
- 1990-11-20 AU AU68967/91A patent/AU624284B2/en not_active Ceased
- 1990-11-20 EP EP91900131A patent/EP0502081B1/en not_active Expired - Lifetime
- 1990-11-20 JP JP3500901A patent/JP3040815B2/ja not_active Expired - Fee Related
- 1990-11-20 US US07/741,522 patent/US5435999A/en not_active Expired - Fee Related
- 1990-11-20 WO PCT/AU1990/000556 patent/WO1991007992A1/en active IP Right Grant
-
1992
- 1992-05-21 NO NO92922008A patent/NO922008L/no unknown
-
1998
- 1998-03-24 HK HK98102462A patent/HK1003475A1/xx not_active IP Right Cessation
-
1999
- 1999-11-18 JP JP11328151A patent/JP2000128791A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0502081A4 (en) | 1993-05-05 |
JP2000128791A (ja) | 2000-05-09 |
ATE138267T1 (de) | 1996-06-15 |
JP3040815B2 (ja) | 2000-05-15 |
HK1003475A1 (en) | 1998-10-30 |
CA2045630A1 (en) | 1991-05-25 |
AU6896791A (en) | 1991-06-26 |
EP0502081B1 (en) | 1996-05-22 |
DE69027123D1 (de) | 1996-06-27 |
EP0502081A1 (en) | 1992-09-09 |
US5435999A (en) | 1995-07-25 |
JPH05502224A (ja) | 1993-04-22 |
AU624284B2 (en) | 1992-06-04 |
DE69027123T2 (de) | 1997-04-24 |
WO1991007992A1 (en) | 1991-06-13 |
NO922008D0 (no) | 1992-05-21 |
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