NO905103D0 - PROCEDURE FOR THE PREPARATION OF A TRANSDERMAL THERAPEUTIC SYSTEM WITH BUPRENORPHINE AS ACTIVE INGREDIENT. - Google Patents

PROCEDURE FOR THE PREPARATION OF A TRANSDERMAL THERAPEUTIC SYSTEM WITH BUPRENORPHINE AS ACTIVE INGREDIENT.

Info

Publication number
NO905103D0
NO905103D0 NO905103A NO905103A NO905103D0 NO 905103 D0 NO905103 D0 NO 905103D0 NO 905103 A NO905103 A NO 905103A NO 905103 A NO905103 A NO 905103A NO 905103 D0 NO905103 D0 NO 905103D0
Authority
NO
Norway
Prior art keywords
buprenorphine
transdermal therapeutic
therapeutic system
weight
procedure
Prior art date
Application number
NO905103A
Other languages
Norwegian (no)
Other versions
NO303107B1 (en
NO905103L (en
Inventor
Thomas Hille
Lothar Deurer
Hans-Rainer Hoffmann
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6394373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO905103(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of NO905103D0 publication Critical patent/NO905103D0/en
Publication of NO905103L publication Critical patent/NO905103L/en
Publication of NO303107B1 publication Critical patent/NO303107B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Abstract

The controlled delivery of buprenorphine or its pharmaceutically compatible salts over at least 24 hours onto the skin is ensured by a transdermal therapeutic system composed of a backing layer which is impermeable to active substance, of an adhesive reservoir layer and, where appropriate, of a protective layer which can be detached again, which system is characterised in that the reservoir layer contains 20-90% by weight of polymeric material, 0.1-30% by weight of plasticiser, 0.1-20% of buprenorphine base or of one of its pharmaceutically acceptable salts and 0.1-30% by weight of solvent for the active substance base.
NO905103A 1989-11-29 1990-11-26 Process for Preparing a Transdermal Therapeutic System with Buprenorphine as an Active Ingredient NO303107B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3939376A DE3939376C1 (en) 1989-11-29 1989-11-29

Publications (3)

Publication Number Publication Date
NO905103D0 true NO905103D0 (en) 1990-11-26
NO905103L NO905103L (en) 1991-05-30
NO303107B1 NO303107B1 (en) 1998-06-02

Family

ID=6394373

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905103A NO303107B1 (en) 1989-11-29 1990-11-26 Process for Preparing a Transdermal Therapeutic System with Buprenorphine as an Active Ingredient

Country Status (25)

Country Link
EP (1) EP0430019B1 (en)
JP (1) JPH0818984B2 (en)
KR (1) KR950015061B1 (en)
AT (1) ATE135205T1 (en)
AU (1) AU632182B2 (en)
CA (1) CA2030178C (en)
CZ (1) CZ282557B6 (en)
DE (2) DE3939376C1 (en)
DK (1) DK0430019T3 (en)
ES (1) ES2086353T3 (en)
FI (1) FI100379B (en)
GR (1) GR3020177T3 (en)
HR (1) HRP930675B1 (en)
HU (1) HU206266B (en)
IE (1) IE73247B1 (en)
IL (1) IL96243A (en)
MY (1) MY105347A (en)
NO (1) NO303107B1 (en)
NZ (1) NZ236191A (en)
PL (1) PL165396B1 (en)
PT (1) PT96028B (en)
SI (1) SI9012260B (en)
SK (1) SK279687B6 (en)
YU (1) YU47956B (en)
ZA (1) ZA909544B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5069909A (en) * 1990-06-20 1991-12-03 Cygnus Therapeutic Systems Transdermal administration of buprenorphine
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
US6344211B1 (en) 1994-12-24 2002-02-05 Lts Lohmann Therapie-Systeme Gmbh Transdermal absorption of active substances from subcooled melts
DE4446600A1 (en) * 1994-12-24 1996-06-27 Lohmann Therapie Syst Lts Transdermal absorption of active ingredients from supercooled melts
JPH1036265A (en) * 1996-07-19 1998-02-10 Nitto Denko Corp Buprenorphine percutaneous absorption preparation
DE19705138A1 (en) * 1997-02-11 1998-08-13 Lohmann Therapie Syst Lts Stretchy transdermal therapeutic system
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
DE19738855C2 (en) 1997-09-05 2001-01-04 Lohmann Therapie Syst Lts Transdermal therapeutic system with adhesive reservoir layer and unidirectional elastic back layer
DE19828273B4 (en) * 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing hormones and crystallization inhibitors
DE19850517B4 (en) 1998-11-03 2004-02-12 Lts Lohmann Therapie-Systeme Ag Use of an active substance-containing transdermal therapeutic system in a combined treatment with and without ultrasound
DE19901085C2 (en) * 1999-01-14 2003-12-18 Lohmann Therapie Syst Lts Transdermal therapeutic system with a self-adhesive matrix containing organic acid addition salts of morphine or morphine type alkaloids
DE19923551A1 (en) * 1999-05-21 2000-11-30 Lohmann Therapie Syst Lts Pharmaceutical preparation with the active ingredient diamorphine and its use in a method for treating opiate addiction
DE10056012A1 (en) * 2000-11-11 2002-05-16 Beiersdorf Ag Carrier material for medical applications, preferably for transdermal therapeutic system, has aluminum film between carrier and self-adhesive coating
DE10056014A1 (en) * 2000-11-11 2002-05-16 Beiersdorf Ag Laminated plaster with active substance, used as transdermal therapeutic system, has impermeable barrier layer on side away from skin and separable carrier layer with adhesive on side towards skin
JP4194277B2 (en) 2002-01-25 2008-12-10 久光製薬株式会社 Method for producing pressure-sensitive adhesive molded body mainly composed of crosslinked polymer
PT1526848E (en) * 2002-08-09 2007-08-08 Gruenenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
DE10237057A1 (en) * 2002-08-09 2004-03-25 Grünenthal GmbH Transdermal therapeutic systems containing buprenorphine, useful in treating pain or urinary incontinence, also containing mu-, kappa- or delta-opioid receptor antagonist to reduce abuse potential
NZ542548A (en) 2003-03-31 2009-04-30 Titan Pharmaceuticals Inc Implantable polymeric device for sustained release of dopamine agonist
ES2295929T3 (en) * 2003-07-25 2008-04-16 Euro-Celtique S.A. TREATMENT OF SUSPENSION OF THE DEPENDENCY.
DE102004009903A1 (en) 2004-02-26 2005-09-22 Grünenthal GmbH Patch with reduced skin irritation
EP1743638A1 (en) 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. Pharmaceutical formulations of substituted pyrazoline compounds
DE102006057083A1 (en) 2005-12-05 2007-06-28 Lg Electronics Inc. Lighting device for a refrigerator
DE102006054731B4 (en) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for administration of the active ingredient buprenorphine and use thereof in pain therapy
DK2640389T3 (en) 2010-11-17 2015-03-09 Hexal Ag Transdermal therapeutic system comprising buprenorphine
DE102011076653A1 (en) 2011-05-27 2012-11-29 Acino Ag Transdermal therapeutic system containing buprenorphine and an alpha hydroxy acid
SG11201403162XA (en) * 2011-12-12 2014-10-30 Lohmann Therapie Syst Lts Transdermal delivery system comprising buprenorphine
DE102012000369A1 (en) 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermal therapeutic system with cholinesterase inhibitor
CN105377245B (en) 2013-06-04 2018-07-17 Lts勒曼治疗系统股份公司 Transdermal delivery system
DE102014013448A1 (en) 2014-09-16 2016-03-17 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermal therapeutic system comprising buprenorphine
US9656441B2 (en) 2015-01-08 2017-05-23 Alfred E. Tiefenbacher ( Gmbh & Co. Kg) Transdermal patch
EP3067050A1 (en) 2015-03-13 2016-09-14 Acino AG Transdermal therapeutic system with an overtape comprising two adhesive layers
CN109045341A (en) * 2018-05-07 2018-12-21 武汉兴嘉业堂医疗科技发展有限公司 A kind of promoting blood circulation and stopping pain pressure sensitive adhesive and preparation method thereof, application

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464378A (en) * 1981-04-28 1984-08-07 University Of Kentucky Research Foundation Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
JPS60123417A (en) * 1983-12-07 1985-07-02 Nitto Electric Ind Co Ltd Drug delivery member
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4806341A (en) * 1985-02-25 1989-02-21 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
DE3634016A1 (en) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg AREA-BASED THERAPEUTIC SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE
JPS632533A (en) * 1986-06-23 1988-01-07 Yamakawa Sangyo Kk Molded sand for precision casting
CH672888A5 (en) * 1986-11-07 1990-01-15 Mepha Ag
ES2036670T3 (en) * 1987-03-09 1993-06-01 Alza Corporation COMPOSITION TO PREVENT A CONTACT ALLERGY BY SIMULTANEOUS ADMINISTRATION OF A CORTICOESTEROID WITH A SENSITIZING PHARMACY.
WO1988009676A1 (en) * 1987-06-01 1988-12-15 Warner-Lambert Company Fatty acids and their small chain esters as penetration enhancers in aqueous systems
DE3843237A1 (en) * 1988-12-22 1990-07-05 Lohmann Therapie Syst Lts TRANSDERMAL THERAPEUTIC SYSTEM WITH AN ANTIADIPOSITUM AS AN ACTIVE INGREDIENT

Also Published As

Publication number Publication date
DE3939376C1 (en) 1991-05-08
EP0430019A3 (en) 1991-09-18
NZ236191A (en) 1993-05-26
ES2086353T3 (en) 1996-07-01
IE904290A1 (en) 1991-06-05
JPH0818984B2 (en) 1996-02-28
AU632182B2 (en) 1992-12-17
PL287989A1 (en) 1991-09-09
KR910009249A (en) 1991-06-28
IL96243A (en) 1994-11-28
ZA909544B (en) 1992-08-26
HUT55643A (en) 1991-06-28
SI9012260B (en) 1998-06-30
JPH03193732A (en) 1991-08-23
AU6569990A (en) 1991-06-06
PL165396B1 (en) 1994-12-30
SK279687B6 (en) 1999-02-11
CA2030178A1 (en) 1991-05-30
CS9005598A2 (en) 1991-12-17
HU206266B (en) 1992-10-28
FI905892A0 (en) 1990-11-29
PT96028A (en) 1991-09-13
ATE135205T1 (en) 1996-03-15
DE59010192D1 (en) 1996-04-18
YU47956B (en) 1996-07-24
HRP930675A2 (en) 1994-10-31
EP0430019A2 (en) 1991-06-05
HRP930675B1 (en) 1999-10-31
FI905892A (en) 1991-05-30
CA2030178C (en) 1995-08-15
NO303107B1 (en) 1998-06-02
KR950015061B1 (en) 1995-12-21
SI9012260A (en) 1997-10-31
YU226090A (en) 1992-12-21
DK0430019T3 (en) 1996-07-22
FI100379B (en) 1997-11-28
IE73247B1 (en) 1997-05-21
PT96028B (en) 1998-02-27
NO905103L (en) 1991-05-30
GR3020177T3 (en) 1996-09-30
CZ282557B6 (en) 1997-08-13
IL96243A0 (en) 1991-08-16
MY105347A (en) 1994-09-30
EP0430019B1 (en) 1996-03-13

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