NO893327L - NEW MICROORGANISM FOR THE DEGRADATION OF MOENOMYCINES AND THE PROCEDURE FOR DEGRADATION AND USE OF THE DEgradation PRODUCTS. - Google Patents

NEW MICROORGANISM FOR THE DEGRADATION OF MOENOMYCINES AND THE PROCEDURE FOR DEGRADATION AND USE OF THE DEgradation PRODUCTS.

Info

Publication number
NO893327L
NO893327L NO89893327A NO893327A NO893327L NO 893327 L NO893327 L NO 893327L NO 89893327 A NO89893327 A NO 89893327A NO 893327 A NO893327 A NO 893327A NO 893327 L NO893327 L NO 893327L
Authority
NO
Norway
Prior art keywords
degradation
moenomycines
procedure
new microorganism
products
Prior art date
Application number
NO89893327A
Other languages
Norwegian (no)
Other versions
NO893327D0 (en
Inventor
Werner Aretz
Dirk Boettger
Gerhard Seibert
Alois Tumulka
Peter Welzel
Kurt Hobert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO893327D0 publication Critical patent/NO893327D0/en
Publication of NO893327L publication Critical patent/NO893327L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

Abstract

It is possible with the aid of a Bacillus species or the appropriate enzymes obtained therefrom to degrade phosphoglycolipid antibiotics. The degradation products of the moenomycins have antibiotic activity or can be used as building block in the synthetic preparation of transglycosylase inhibitors.
NO89893327A 1988-08-20 1989-08-18 NEW MICROORGANISM FOR THE DEGRADATION OF MOENOMYCINES AND THE PROCEDURE FOR DEGRADATION AND USE OF THE DEgradation PRODUCTS. NO893327L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3828337 1988-08-20

Publications (2)

Publication Number Publication Date
NO893327D0 NO893327D0 (en) 1989-08-18
NO893327L true NO893327L (en) 1990-02-21

Family

ID=6361268

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89893327A NO893327L (en) 1988-08-20 1989-08-18 NEW MICROORGANISM FOR THE DEGRADATION OF MOENOMYCINES AND THE PROCEDURE FOR DEGRADATION AND USE OF THE DEgradation PRODUCTS.

Country Status (16)

Country Link
EP (1) EP0355679B1 (en)
JP (2) JP2863557B2 (en)
KR (1) KR900003361A (en)
AT (1) ATE134641T1 (en)
AU (2) AU619034B2 (en)
DE (1) DE58909610D1 (en)
DK (1) DK407789A (en)
ES (1) ES2085855T3 (en)
FI (1) FI893878A (en)
GR (1) GR3019332T3 (en)
IL (1) IL91354A0 (en)
NO (1) NO893327L (en)
NZ (1) NZ230352A (en)
PH (1) PH26511A (en)
PT (1) PT91469B (en)
ZA (1) ZA896310B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE134641T1 (en) * 1988-08-20 1996-03-15 Hoechst Ag NEW MICROORGANISM FOR THE DEGRADATION OF MOENOMYCINS, METHOD FOR DEGRADATION AND THE USE OF THE DEGRADATION PRODUCTS
US5316929A (en) * 1991-03-08 1994-05-31 Hoechst Aktiengesellschaft Process for the preparation of MA
DE59208669D1 (en) * 1991-03-08 1997-08-14 Hoechst Ag Process for producing MA
EP0652205A3 (en) * 1993-11-04 1995-08-30 Hoechst Ag Moenomycin degradation products containing hydroxylated or oxidized lateral lipid chain and moenomycin analogs, process for preparing and their use.
DE19709897A1 (en) * 1997-03-11 1998-09-17 Hoechst Ag Bismuth salts of antibiotics of the moenomycin group, process for their preparation, their use and medicaments containing such salts
EP0872556A3 (en) * 1997-04-17 2000-06-14 Hoechst Aktiengesellschaft Process for the preparation of moenomycin A
EP1069130B1 (en) * 1999-07-15 2004-08-11 Hoechst Marion Roussel Moenomycin A Derivatives, their preparation, and use as antibacterial products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6601300A (en) * 1966-02-01 1967-08-02 Stamicarbon
DE3467171D1 (en) * 1983-05-21 1987-12-10 Hoechst Ag Moenomycin-a derivatives, their preparation and their use as antibiotics
ATE134641T1 (en) * 1988-08-20 1996-03-15 Hoechst Ag NEW MICROORGANISM FOR THE DEGRADATION OF MOENOMYCINS, METHOD FOR DEGRADATION AND THE USE OF THE DEGRADATION PRODUCTS

Also Published As

Publication number Publication date
ZA896310B (en) 1990-04-25
AU619034B2 (en) 1992-01-16
DE58909610D1 (en) 1996-04-04
IL91354A0 (en) 1990-03-19
NZ230352A (en) 1991-07-26
AU635452B2 (en) 1993-03-18
KR900003361A (en) 1990-03-26
EP0355679A3 (en) 1991-07-24
EP0355679B1 (en) 1996-02-28
DK407789D0 (en) 1989-08-18
AU3998589A (en) 1990-02-22
ATE134641T1 (en) 1996-03-15
PT91469B (en) 1995-05-04
FI893878A (en) 1990-02-21
ES2085855T3 (en) 1996-06-16
PH26511A (en) 1992-08-07
AU8835391A (en) 1992-02-06
JPH1171323A (en) 1999-03-16
GR3019332T3 (en) 1996-06-30
EP0355679A2 (en) 1990-02-28
JP2863557B2 (en) 1999-03-03
FI893878A0 (en) 1989-08-17
JPH02150273A (en) 1990-06-08
DK407789A (en) 1990-02-21
NO893327D0 (en) 1989-08-18
PT91469A (en) 1990-03-08

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