NO870668L - Fremgangsmÿte for gjenvinning av mikrobielt fremstilt rekombinant ricin toxin a kjede. - Google Patents

Fremgangsmÿte for gjenvinning av mikrobielt fremstilt rekombinant ricin toxin a kjede.

Info

Publication number
NO870668L
NO870668L NO870668A NO870668A NO870668L NO 870668 L NO870668 L NO 870668L NO 870668 A NO870668 A NO 870668A NO 870668 A NO870668 A NO 870668A NO 870668 L NO870668 L NO 870668L
Authority
NO
Norway
Prior art keywords
chain
ricin toxin
recombinant ricin
recovering microbial
manufactured recombinant
Prior art date
Application number
NO870668A
Other languages
English (en)
Other versions
NO870668D0 (no
Inventor
Robert Ferris
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of NO870668D0 publication Critical patent/NO870668D0/no
Publication of NO870668L publication Critical patent/NO870668L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809Fused cells, e.g. hybridoma

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO870668A 1986-03-06 1987-02-19 Fremgangsmÿte for gjenvinning av mikrobielt fremstilt rekombinant ricin toxin a kjede. NO870668L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83684886A 1986-03-06 1986-03-06
US06/905,283 US4689401A (en) 1986-03-06 1986-09-09 Method of recovering microbially produced recombinant ricin toxin a chain

Publications (2)

Publication Number Publication Date
NO870668D0 NO870668D0 (no) 1987-02-19
NO870668L true NO870668L (no) 1987-09-07

Family

ID=27125896

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870668A NO870668L (no) 1986-03-06 1987-02-19 Fremgangsmÿte for gjenvinning av mikrobielt fremstilt rekombinant ricin toxin a kjede.

Country Status (7)

Country Link
US (1) US4689401A (no)
EP (1) EP0237297A1 (no)
AU (1) AU596153B2 (no)
CA (1) CA1308680C (no)
DK (1) DK118887A (no)
FI (1) FI870981A (no)
NO (1) NO870668L (no)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1289880C (en) * 1985-12-06 1991-10-01 Jeffrey L. Winkelhake Anti-human ovarian cancer immunotoxins and methods of use thereof
US4956453A (en) * 1985-12-06 1990-09-11 Cetus Corporation Anti-human ovarian cancer immunotoxins and methods of use thereof
IL80972A (en) * 1985-12-20 1992-08-18 Sanofi Sa Modified ribosome-inactivating glycoproteins,their preparation,immunotoxins containing them and pharmaceutical compositions containing such immunotoxins
IL80973A (en) * 1985-12-20 1992-08-18 Sanofi Sa Modified ribosome-inactivating glycoproteins,their preparation,immunotoxins containing them and pharmaceutical compositions containing such immunotoxins
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US4771128A (en) * 1986-10-10 1988-09-13 Cetus Corporation Method of purifying toxin conjugates using hydrophobic interaction chromatography
US4985541A (en) * 1987-04-10 1991-01-15 Zymogenetics, Inc. Novel cytotoxic protein
NZ225372A (en) * 1987-07-17 1991-04-26 Xoma Corp Immunotoxin composition comprising purified ricin-a-chain species
EP0341304A4 (en) * 1987-11-24 1991-01-30 Genetics Institute, Inc. Improved ricin molecules and ricin toxin conjugates
GB2253210B (en) * 1991-02-26 1995-06-07 Ici Plc Soluble heterologous polypeptide produced by culture of recombinant microorganisms
USH1985H1 (en) 1992-01-09 2001-08-07 The United States Of America As Represented By The Secretary Of The Navy Method for detecting biological toxins
US5453271A (en) * 1993-06-28 1995-09-26 The United States Of America As Represented By The Secretary Of The Army Vaccine against ricin toxin
US5437986A (en) * 1994-06-22 1995-08-01 Schering Corporation Extraction of heterologous insoluble proteins from bacteria
ATE401348T1 (de) 1999-05-27 2008-08-15 Us Gov Health & Human Serv Immunokonjugate mit hoher bindungsaffinität
US6869787B2 (en) 2002-02-27 2005-03-22 The United States Of America As Represented By The Secretary Of The Army Ricin vaccine and methods of making and using thereof
EP2204385A1 (en) 2003-11-25 2010-07-07 The Government Of U.S.A, As Represented By Secretary, Department of Health and Human Sevices Pseudomonas exotoxin A mutants and uses thereof
EP2250196B1 (en) 2008-01-31 2012-12-26 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Engineered constant domain molecule of an antibody
EP2334701A4 (en) 2008-10-16 2014-01-08 Univ Pittsburgh FULLY HUMAN ANTIBODIES AGAINST ANTIGENES ASSOCIATED WITH MELANOMA OF HIGH MOLECULAR WEIGHT AND USES THEREOF
CN104689314B (zh) 2010-06-16 2018-02-02 高等教育联邦系统-匹兹堡大学 内质蛋白的抗体及其用途
SG187587A1 (en) 2010-07-30 2013-03-28 Medimmune Llc Method for purifying active polypeptides or immunoconjugates
EP2998320B1 (en) 2011-04-19 2018-07-18 The United States of America, as represented by the Secretary, Department of Health and Human Services Human monoclonal antibodies specific for glypican-3 and use thereof
AU2012306341B2 (en) 2011-09-09 2017-08-31 Cambridge Enterprise Limited Anti-Siglec-15 antibodies and uses thereof
WO2013039916A1 (en) 2011-09-12 2013-03-21 The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services Compositions for and methods of treatment and enhanced detection of non-pituitary tumors
EP3275902A1 (en) 2011-10-04 2018-01-31 IGEM Therapeutics Limited Ige anti-hmw-maa antibody
WO2013138643A1 (en) 2012-03-16 2013-09-19 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Soluble engineered monomeric fc
US9409994B2 (en) 2012-06-01 2016-08-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High-affinity monoclonal antibodies to glypican-3 and use thereof
EP3327037B1 (en) 2012-08-21 2019-10-09 The U.S.A. as represented by the Secretary, Department of Health and Human Services Mesothelin domain-specific monoclonal antibodies and use thereof
CA2885761C (en) 2012-09-27 2021-09-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Mesothelin antibodies and methods for eliciting potent antitumor activity
CN105007937B (zh) 2012-12-20 2019-11-19 米迪缪尼有限公司 生产免疫偶联物的方法
CA2925393C (en) 2013-10-11 2023-03-07 Dimiter Dimitrov Tem8 antibodies and their use
EP3066118B1 (en) 2013-11-06 2020-01-08 The U.S.A. as represented by the Secretary, Department of Health and Human Services Alk antibodies, conjugates, and chimeric antigen receptors, and their use
JP6811706B2 (ja) 2014-07-31 2021-01-13 ザ ホンコン ユニヴァーシティ オブ サイエンス アンド テクノロジー Epha4に対するヒトモノクローナル抗体及びそれらの使用
ES2961346T3 (es) 2015-06-12 2024-03-11 Lentigen Tech Inc Procedimiento para tratar cáncer con células T modificadas genéticamente
CN114181960B (zh) 2015-10-09 2024-08-23 美天施生物科技有限公司 嵌合抗原受体和使用方法
WO2017196847A1 (en) 2016-05-10 2017-11-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
WO2017214182A1 (en) 2016-06-07 2017-12-14 The United States Of America. As Represented By The Secretary, Department Of Health & Human Services Fully human antibody targeting pdi for cancer immunotherapy
CA3031559A1 (en) 2016-08-02 2018-02-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibodies targeting glypican-2 (gpc2) and use thereof
US11453712B2 (en) 2016-09-02 2022-09-27 Lentigen Technology Inc. Compositions and methods for treating cancer with DuoCARs
US11236171B2 (en) 2016-12-21 2022-02-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies specific for FLT3 and uses thereof
CN117946283A (zh) 2017-01-09 2024-04-30 莱蒂恩技术公司 用于用抗间皮素免疫治疗癌症的组合物和方法
EP3601356A1 (en) 2017-03-24 2020-02-05 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd33 immunotherapy
US11389480B2 (en) 2017-05-19 2022-07-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibody targeting TNFR2 for cancer immunotherapy
WO2019005208A1 (en) 2017-06-30 2019-01-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services ANTIBODIES TO HUMAN MESOTHELIN AND USES IN ANTICANCER THERAPY
CA3066953A1 (en) 2017-06-30 2019-01-03 Lentigen Technology, Inc. Human monoclonal antibodies specific for cd33 and methods of their use
WO2019028051A1 (en) 2017-07-31 2019-02-07 Lentigen Technology, Inc. COMPOSITIONS AND METHODS FOR TREATING CANCER BY ANTI-CD19 / CD20 IMMUNOTHERAPY
JP7035170B2 (ja) 2017-09-15 2022-03-14 レンティジェン・テクノロジー・インコーポレイテッド 抗cd19免疫療法によりがんを処置するための組成物および方法
JP7275118B2 (ja) 2017-10-16 2023-05-17 レンティジェン・テクノロジー・インコーポレイテッド 抗cd22免疫療法によってがんを処置するための組成物および方法
CA3086612A1 (en) 2017-12-20 2019-06-27 Lentigen Technology, Inc. Compositions and methods for treating hiv/aids with immunotherapy
AU2019301675A1 (en) 2018-07-12 2021-01-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Affinity matured CD22-specific monoclonal antibody and uses thereof
AU2019317565A1 (en) 2018-08-08 2021-02-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High affinity monoclonal antibodies targeting glypican-2 and uses thereof
EP3853254A1 (en) 2018-09-20 2021-07-28 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd123 immunotherapy
JP7546554B2 (ja) 2018-09-26 2024-09-06 レンティジェン・テクノロジー・インコーポレイテッド 抗cd19/cd22免疫療法によりがんを処置するための組成物および方法
CA3121244A1 (en) 2018-11-30 2020-06-04 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd38 immunotherapy
CA3125484A1 (en) 2019-01-08 2020-07-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cross-species single domain antibodies targeting mesothelin for treating solid tumors
AU2020212534A1 (en) 2019-01-22 2021-07-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services High affinity monoclonal antibodies targeting glypican-1 and methods of use
WO2020181164A1 (en) 2019-03-06 2020-09-10 Lentigen Technology, Inc. Compositions and methods for treating cancer with self-driving chimeric antigen receptors
CN118345101A (zh) 2019-05-30 2024-07-16 莱蒂恩技术公司 用于用抗bcma免疫治疗来治疗癌症的组合物和方法
CA3142833A1 (en) 2019-07-02 2021-01-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibodies that bind egfrviii and their use
EP4031250A1 (en) 2019-10-22 2022-07-27 The United States of America, as represented by the Secretary, Department of Health and Human Services High affinity nanobodies targeting b7h3 (cd276) for treating multiple solid tumors
WO2021173674A1 (en) 2020-02-26 2021-09-02 A2 Biotherapeutics, Inc. Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
WO2021262723A1 (en) 2020-06-22 2021-12-30 Lentigen Technology, Inc. Compositions and methods for treating cancer with tslpr-cd19 or tslpr-cd22 immunotherapy
US20230391852A1 (en) 2020-10-26 2023-12-07 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Single domain antibodies targeting sars coronavirus spike protein and uses thereof
WO2022099026A1 (en) 2020-11-05 2022-05-12 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd19/cd22 immunotherapy
WO2022232612A1 (en) 2021-04-29 2022-11-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Lassa virus-specific nanobodies and methods of their use
CN117500831A (zh) 2021-06-09 2024-02-02 美国政府(由卫生和人类服务部的部长所代表) 用于治疗实体瘤的靶向pd-l1的跨物种单结构域抗体
WO2023076881A1 (en) 2021-10-26 2023-05-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Single domain antibodies targeting the s2 subunit of sars-cov-2 spike protein
US11590169B1 (en) 2022-03-02 2023-02-28 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-CD123 immunotherapy
US20230338424A1 (en) 2022-03-02 2023-10-26 Lentigen Technology, Inc. Compositions and Methods for Treating Cancer with Anti-CD123 Immunotherapy
WO2024026107A2 (en) 2022-07-28 2024-02-01 Lentigen Technology, Inc. Chimeric antigen receptor therapies for treating solid tumors
WO2024044743A1 (en) 2022-08-26 2024-02-29 Lentigen Technology, Inc. Compositions and methods for treating cancer with fully human anti-cd20/cd19 immunotherapy
WO2024050399A1 (en) 2022-09-01 2024-03-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Single domain antibodies targeting hpv e6/e7 oncogenic peptide/mhc complexes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2437213A1 (fr) * 1978-09-28 1980-04-25 Cm Ind Produits cytotoxiques formes par liaison covalente de la chaine a de la ricine avec un anticorps et leur procede de preparation
FR2504010B1 (fr) * 1981-04-15 1985-10-25 Sanofi Sa Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
FR2536997B1 (fr) * 1982-03-11 1987-08-07 Sanofi Sa Medicaments cytotoxiques comportant au moins une immunotoxine et de la methylamine
GR79124B (no) * 1982-12-22 1984-10-02 Genentech Inc
ATE68703T1 (de) * 1984-02-08 1991-11-15 Cetus Corp Toxinkonjugate.
US4590071A (en) * 1984-09-25 1986-05-20 Xoma Corporation Human melanoma specific immunotoxins
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
CA1286843C (en) * 1985-10-30 1991-07-23 Leo S. Lin Purification method for proteins
ATE169672T1 (de) * 1986-03-07 1998-08-15 Chiron Corp Rekombinantes ricin-toxin

Also Published As

Publication number Publication date
DK118887D0 (da) 1987-03-06
AU596153B2 (en) 1990-04-26
NO870668D0 (no) 1987-02-19
AU6973887A (en) 1987-09-10
US4689401A (en) 1987-08-25
DK118887A (da) 1987-09-07
FI870981A (fi) 1987-09-07
CA1308680C (en) 1992-10-13
EP0237297A1 (en) 1987-09-16
FI870981A0 (fi) 1987-03-05

Similar Documents

Publication Publication Date Title
NO870668L (no) Fremgangsmÿte for gjenvinning av mikrobielt fremstilt rekombinant ricin toxin a kjede.
NO854261L (no) 9-amino-1,2,3,4-tetrahydroakridin-1-01 og beslektede forbindelser og fremgangsmaate til fremstilling derav.
DZ1504A1 (fr) Méthode de synthèse améliorée.
NO874439D0 (no) Gasstetningsanordning for en aksel.
DE3886323D1 (de) Interpolationsverfahren.
DE3850719D1 (de) Direkt angetriebenes Servoventil.
NO904797L (no) Roerkrave.
DE3574529D1 (de) Heterouebergangs-transistoren.
DE68914094D1 (de) Immunoanalyseverfahren.
DE68912648D1 (de) Bauverfahren.
NO913359D0 (no) Tetningsanordning for avtetting mellom konsentriske, roerformete legemer i en broenn.
DK0564738T3 (da) Smøremateriale og en fremgangsmåde til fremstilling deraf.
FI882835A (fi) Pneumatisk, med slagverkan, saerskilt med ett slag arbetande anordning.
DE58903125D1 (de) Sonnendach.
NO872629L (no) Forbedret fusjonsmetode.
DE68910956D1 (de) Mit toxin modifizierter antikörper.
DE58905991D1 (de) Dichtungsmanschette.
FI894237A (fi) Menetelmä antibiootin GE 2270 tekijä A:n valmistamiseksi
FI882943A0 (fi) Pneumatisk, med slagverkan, saerskilt med ett slag arbetande anordning.
KR900700427A (ko) 페녹시페녹시프로피오네이트, 이의 중간체 및 제조방법
FI892221A (fi) Metod foer framstaellning av optiskt aktiva naftotiazepinoner.
DE3584107D1 (de) Polyphosphazen-verfahren.
FI884287A0 (fi) Metod foer tillverkning av cyklodextriner innehaollande maltodextriner, staerkelse- och maltossiraper.
DE58902524D1 (de) Schiebedach.
DE68909212D1 (de) Trennverfahren.