NO861964L - Aminomalonyl-alaninforbindelser, samt anvendelse av dem som diett-soetemidler. - Google Patents
Aminomalonyl-alaninforbindelser, samt anvendelse av dem som diett-soetemidler.Info
- Publication number
- NO861964L NO861964L NO861964A NO861964A NO861964L NO 861964 L NO861964 L NO 861964L NO 861964 A NO861964 A NO 861964A NO 861964 A NO861964 A NO 861964A NO 861964 L NO861964 L NO 861964L
- Authority
- NO
- Norway
- Prior art keywords
- mmol
- ester
- alanine
- solution
- etoac
- Prior art date
Links
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- OCYLOGGHVKOFCX-GSVOUGTGSA-N 3-[amino-[(1R)-1-carboxyethyl]amino]-3-oxopropanoic acid Chemical class NN([C@H](C)C(=O)O)C(CC(=O)O)=O OCYLOGGHVKOFCX-GSVOUGTGSA-N 0.000 claims 1
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- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 229960004132 diethyl ether Drugs 0.000 description 1
- MKYNHKOAYQRSBD-UHFFFAOYSA-N dioxouranium;nitric acid Chemical compound O=[U]=O.O[N+]([O-])=O.O[N+]([O-])=O MKYNHKOAYQRSBD-UHFFFAOYSA-N 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000037433 frameshift Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 231100000304 hepatotoxicity Toxicity 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007056 liver toxicity Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 235000019656 metallic taste Nutrition 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 230000003228 microsomal effect Effects 0.000 description 1
- VLAPMBHFAWRUQP-UHFFFAOYSA-L molybdic acid Chemical compound O[Mo](O)(=O)=O VLAPMBHFAWRUQP-UHFFFAOYSA-L 0.000 description 1
- 231100000417 nephrotoxicity Toxicity 0.000 description 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229960005190 phenylalanine Drugs 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 239000003891 promutagen Substances 0.000 description 1
- QDQVXVRZVCTVHE-RXMQYKEDSA-N propan-2-yl (2r)-2-aminopropanoate Chemical compound CC(C)OC(=O)[C@@H](C)N QDQVXVRZVCTVHE-RXMQYKEDSA-N 0.000 description 1
- YAQKNCSWDMGPOY-NUBCRITNSA-N propan-2-yl (2r)-2-aminopropanoate;hydrochloride Chemical compound Cl.CC(C)OC(=O)[C@@H](C)N YAQKNCSWDMGPOY-NUBCRITNSA-N 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000007363 ring formation reaction Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/70—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter
- A23L2/78—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter by ion-exchange
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Confectionery (AREA)
- Seasonings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/651,859 US4564528A (en) | 1984-09-18 | 1984-09-18 | Aminomalonyl alanine compounds and use as dietary sweeteners |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO861964L true NO861964L (no) | 1986-05-16 |
Family
ID=24614499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO861964A NO861964L (no) | 1984-09-18 | 1986-05-16 | Aminomalonyl-alaninforbindelser, samt anvendelse av dem som diett-soetemidler. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US4564528A (fi) |
| EP (1) | EP0195047A4 (fi) |
| JP (1) | JPS62500381A (fi) |
| KR (1) | KR870700294A (fi) |
| AU (1) | AU603052B2 (fi) |
| CA (1) | CA1259448A (fi) |
| DK (1) | DK225586D0 (fi) |
| FI (1) | FI862059A (fi) |
| IL (1) | IL76401A (fi) |
| NO (1) | NO861964L (fi) |
| NZ (1) | NZ213515A (fi) |
| WO (1) | WO1986001690A1 (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5175009A (en) * | 1991-10-17 | 1992-12-29 | Wm. Wrigley Jr. Company | Stabilized chewing gum containing acidified humectant |
| US5286509A (en) * | 1992-06-22 | 1994-02-15 | The Coca-Cola Company | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners |
| WO2004075663A1 (en) * | 2003-02-26 | 2004-09-10 | Firmenich Sa | Aminoacid derivatives of dicarboxylic acids as flavor ingredients |
| US20050233058A1 (en) * | 2004-01-29 | 2005-10-20 | Eric Frerot | Aminoacid derivatives of dicarboxylic acids as flavor ingredients |
| US8945652B2 (en) * | 2005-11-23 | 2015-02-03 | The Coca-Cola Company | High-potency sweetener for weight management and compositions sweetened therewith |
| US8940350B2 (en) * | 2005-11-23 | 2015-01-27 | The Coca-Cola Company | Cereal compositions comprising high-potency sweeteners |
| US20070116833A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith |
| US8377491B2 (en) * | 2005-11-23 | 2013-02-19 | The Coca-Cola Company | High-potency sweetener composition with vitamin and compositions sweetened therewith |
| US8435587B2 (en) * | 2005-11-23 | 2013-05-07 | The Coca-Cola Company | High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith |
| US9101160B2 (en) * | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| US8524303B2 (en) * | 2005-11-23 | 2013-09-03 | The Coca-Cola Company | High-potency sweetener composition with phytosterol and compositions sweetened therewith |
| US20070116829A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Pharmaceutical Composition with High-Potency Sweetener |
| US8435588B2 (en) * | 2005-11-23 | 2013-05-07 | The Coca-Cola Company | High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith |
| US20070116839A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith |
| US8367138B2 (en) * | 2005-11-23 | 2013-02-05 | The Coca-Cola Company | Dairy composition with high-potency sweetener |
| US8524304B2 (en) * | 2005-11-23 | 2013-09-03 | The Coca-Cola Company | High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith |
| US8940351B2 (en) * | 2005-11-23 | 2015-01-27 | The Coca-Cola Company | Baked goods comprising high-potency sweetener |
| JP2009517022A (ja) * | 2005-11-23 | 2009-04-30 | ザ・コカ−コーラ・カンパニー | 改善された経時的プロファイル及び／又は香味プロファイルを有する天然高甘味度甘味料組成物、その配合方法、および使用 |
| US8512789B2 (en) * | 2005-11-23 | 2013-08-20 | The Coca-Cola Company | High-potency sweetener composition with dietary fiber and compositions sweetened therewith |
| US20070116800A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Chewing Gum with High-Potency Sweetener |
| US8017168B2 (en) * | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US29682A (en) | 1860-08-21 | Feed-motion foe | ||
| US3492131A (en) * | 1966-04-18 | 1970-01-27 | Searle & Co | Peptide sweetening agents |
| US3475403A (en) * | 1967-01-20 | 1969-10-28 | Searle & Co | Aspartic acid containing dipeptide lower alkyl esters |
| GB1299265A (en) * | 1970-06-04 | 1972-12-13 | Ici Ltd | (alpha-CARBOXY)GLYCYL DIPEPTIDE DERIVATIVES |
| JPS4828068B1 (fi) * | 1970-06-24 | 1973-08-29 | ||
| US3753739A (en) * | 1970-11-05 | 1973-08-21 | Alberto Culver Co | Low calorie dry sweetener composition |
| JPS4828068U (fi) * | 1971-08-09 | 1973-04-05 | ||
| US4029701A (en) * | 1972-03-30 | 1977-06-14 | General Foods Corporation | Sweetening with hydrohalide salts of dipeptide sweeteners |
| JPS4913372A (fi) * | 1972-06-01 | 1974-02-05 | ||
| US4059706A (en) * | 1974-03-07 | 1977-11-22 | General Foods Corporation | Spray-dried L-aspartic acid derivatives |
| US4411925A (en) * | 1980-01-21 | 1983-10-25 | Pfizer Inc. | Branched amides of L-aspartyl-d-amino acid dipeptides |
| US4564548A (en) * | 1984-11-21 | 1986-01-14 | Jacob Fast | Cover strip for display shelf |
-
1984
- 1984-09-18 US US06/651,859 patent/US4564528A/en not_active Expired - Fee Related
-
1985
- 1985-09-15 IL IL76401A patent/IL76401A/xx unknown
- 1985-09-17 NZ NZ213515A patent/NZ213515A/xx unknown
- 1985-09-18 CA CA000491073A patent/CA1259448A/en not_active Expired
- 1985-09-18 AU AU48619/85A patent/AU603052B2/en not_active Ceased
- 1985-09-18 US US06/893,551 patent/US4714619A/en not_active Expired - Fee Related
- 1985-09-18 WO PCT/US1985/001764 patent/WO1986001690A1/en not_active Application Discontinuation
- 1985-09-18 EP EP19850904743 patent/EP0195047A4/en not_active Withdrawn
- 1985-09-18 JP JP60504248A patent/JPS62500381A/ja active Pending
-
1986
- 1986-05-15 DK DK225586A patent/DK225586D0/da not_active Application Discontinuation
- 1986-05-16 NO NO861964A patent/NO861964L/no unknown
- 1986-05-16 FI FI862059A patent/FI862059A/fi not_active Application Discontinuation
- 1986-05-17 KR KR860700276A patent/KR870700294A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI862059A0 (fi) | 1986-05-16 |
| KR870700294A (ko) | 1987-12-28 |
| DK225586A (da) | 1986-05-15 |
| CA1259448A (en) | 1989-09-12 |
| US4564528A (en) | 1986-01-14 |
| EP0195047A4 (en) | 1988-05-31 |
| NZ213515A (en) | 1989-06-28 |
| AU4861985A (en) | 1986-04-08 |
| FI862059A (fi) | 1986-05-16 |
| WO1986001690A1 (en) | 1986-03-27 |
| DK225586D0 (da) | 1986-05-15 |
| US4714619A (en) | 1987-12-22 |
| AU603052B2 (en) | 1990-11-08 |
| EP0195047A1 (en) | 1986-09-24 |
| JPS62500381A (ja) | 1987-02-19 |
| IL76401A0 (en) | 1986-01-31 |
| IL76401A (en) | 1989-07-31 |
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