NO744513L - - Google Patents

Info

Publication number

NO744513L

NO744513L NO744513A NO744513A NO744513L NO 744513 L NO744513 L NO 744513L NO 744513 A NO744513 A NO 744513A NO 744513 A NO744513 A NO 744513A NO 744513 L NO744513 L NO 744513L

Authority

NO

Norway

Prior art keywords

weight

dental care

toothpaste

monofluorophosphate

synthetic

Prior art date

1974-12-13

Links

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• 239000000606 toothpaste Substances 0.000 claims description 17
• 229940034610 toothpaste Drugs 0.000 claims description 16
• 239000003795 chemical substances by application Substances 0.000 claims description 15
• 238000000034 method Methods 0.000 claims description 15
• 229910002028 silica xerogel Inorganic materials 0.000 claims description 13
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 11
• 229940074371 monofluorophosphate Drugs 0.000 claims description 10
• AZJYLVAUMGUUBL-UHFFFAOYSA-A u1qj22mc8e Chemical compound [F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[F-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].O=[Si]=O.O=[Si]=O.O=[Si]=O.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3 AZJYLVAUMGUUBL-UHFFFAOYSA-A 0.000 claims description 10
• HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 8
• 239000004615 ingredient Substances 0.000 claims description 8
• 239000002562 thickening agent Substances 0.000 claims description 7
• 239000000080 wetting agent Substances 0.000 claims description 7
• 239000003349 gelling agent Substances 0.000 claims description 6
• 239000000203 mixture Substances 0.000 claims description 6
• 230000008719 thickening Effects 0.000 claims description 5
• 239000012905 visible particle Substances 0.000 claims description 5
• 235000011187 glycerol Nutrition 0.000 claims description 4
• XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 claims description 3
• FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
• FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
• 239000002245 particle Substances 0.000 claims description 3
• 229960004711 sodium monofluorophosphate Drugs 0.000 claims description 3
• 239000000600 sorbitol Substances 0.000 claims description 3
• 238000002156 mixing Methods 0.000 claims description 2
• 239000004927 clay Substances 0.000 claims 2
• 239000000551 dentifrice Substances 0.000 description 21
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
• 229940094522 laponite Drugs 0.000 description 9
• XCOBTUNSZUJCDH-UHFFFAOYSA-B lithium magnesium sodium silicate Chemical compound [Li+].[Li+].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Na+].[Na+].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].[Mg+2].O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3.O1[Si](O2)([O-])O[Si]3([O-])O[Si]1([O-])O[Si]2([O-])O3 XCOBTUNSZUJCDH-UHFFFAOYSA-B 0.000 description 9
• VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 8
• 239000000047 product Substances 0.000 description 5
• 239000000377 silicon dioxide Substances 0.000 description 4
• 238000003756 stirring Methods 0.000 description 4
• 238000003860 storage Methods 0.000 description 4
• DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
• 239000011230 binding agent Substances 0.000 description 3
• 239000000796 flavoring agent Substances 0.000 description 3
• 238000004519 manufacturing process Methods 0.000 description 3
• 239000000725 suspension Substances 0.000 description 3
• YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 2
• -1 alkali metal salt Chemical class 0.000 description 2
• 239000000084 colloidal system Substances 0.000 description 2
• 150000001875 compounds Chemical class 0.000 description 2
• 239000006185 dispersion Substances 0.000 description 2
• 239000003814 drug Substances 0.000 description 2
• 239000012467 final product Substances 0.000 description 2
• 235000019634 flavors Nutrition 0.000 description 2
• 229910052731 fluorine Inorganic materials 0.000 description 2
• 239000011737 fluorine Substances 0.000 description 2
• 239000004088 foaming agent Substances 0.000 description 2
• 235000003599 food sweetener Nutrition 0.000 description 2
• 239000000463 material Substances 0.000 description 2
• 229920001223 polyethylene glycol Polymers 0.000 description 2
• 238000002360 preparation method Methods 0.000 description 2
• 239000003755 preservative agent Substances 0.000 description 2
• 230000000069 prophylactic effect Effects 0.000 description 2
• 150000003839 salts Chemical class 0.000 description 2
• 235000012239 silicon dioxide Nutrition 0.000 description 2
• 239000003765 sweetening agent Substances 0.000 description 2
• 238000012360 testing method Methods 0.000 description 2
• 229940124597 therapeutic agent Drugs 0.000 description 2
• 241000416162 Astragalus gummifer Species 0.000 description 1
• KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
• 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
• 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
• 229920000161 Locust bean gum Polymers 0.000 description 1
• 229920000881 Modified starch Polymers 0.000 description 1
• 239000004909 Moisturizer Substances 0.000 description 1
• 239000002202 Polyethylene glycol Substances 0.000 description 1
• 229920001615 Tragacanth Polymers 0.000 description 1
• DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
• 238000005273 aeration Methods 0.000 description 1
• 229910052783 alkali metal Inorganic materials 0.000 description 1
• 229910052782 aluminium Inorganic materials 0.000 description 1
• XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
• 239000003242 anti bacterial agent Substances 0.000 description 1
• 229940088710 antibiotic agent Drugs 0.000 description 1
• 239000003212 astringent agent Substances 0.000 description 1
• 230000001680 brushing effect Effects 0.000 description 1
• 239000000872 buffer Substances 0.000 description 1
• 239000001768 carboxy methyl cellulose Substances 0.000 description 1
• 239000000679 carrageenan Substances 0.000 description 1
• 235000010418 carrageenan Nutrition 0.000 description 1
• 229920001525 carrageenan Polymers 0.000 description 1
• 229940113118 carrageenan Drugs 0.000 description 1
• 239000012459 cleaning agent Substances 0.000 description 1
• 238000004040 coloring Methods 0.000 description 1
• 239000013256 coordination polymer Substances 0.000 description 1
• 239000003599 detergent Substances 0.000 description 1
• 230000002542 deteriorative effect Effects 0.000 description 1
• 238000002474 experimental method Methods 0.000 description 1
• 238000001125 extrusion Methods 0.000 description 1
• 229940091249 fluoride supplement Drugs 0.000 description 1
• SKSIDEOZXDVBGN-UHFFFAOYSA-N fluoro dihydrogen phosphate Chemical compound OP(O)(=O)OF SKSIDEOZXDVBGN-UHFFFAOYSA-N 0.000 description 1
• 230000002070 germicidal effect Effects 0.000 description 1
• KWLMIXQRALPRBC-UHFFFAOYSA-L hectorite Chemical compound [Li+].[OH-].[OH-].[Na+].[Mg+2].O1[Si]2([O-])O[Si]1([O-])O[Si]([O-])(O1)O[Si]1([O-])O2 KWLMIXQRALPRBC-UHFFFAOYSA-L 0.000 description 1
• 229910000271 hectorite Inorganic materials 0.000 description 1
• ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
• 229960004068 hexachlorophene Drugs 0.000 description 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
• 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
• 150000002500 ions Chemical class 0.000 description 1
• 239000000711 locust bean gum Substances 0.000 description 1
• 235000010420 locust bean gum Nutrition 0.000 description 1
• 235000019426 modified starch Nutrition 0.000 description 1
• 230000001333 moisturizer Effects 0.000 description 1
• 229940093430 polyethylene glycol 1500 Drugs 0.000 description 1
• 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
• 230000001698 pyrogenic effect Effects 0.000 description 1
• CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
• 229940081974 saccharin Drugs 0.000 description 1
• 235000019204 saccharin Nutrition 0.000 description 1
• 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
• 239000000344 soap Substances 0.000 description 1
• 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
• 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
• ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 description 1
• 229960002799 stannous fluoride Drugs 0.000 description 1
• 239000000126 substance Substances 0.000 description 1
• 239000000271 synthetic detergent Substances 0.000 description 1
• 230000009974 thixotropic effect Effects 0.000 description 1
• 239000000196 tragacanth Substances 0.000 description 1
• 235000010487 tragacanth Nutrition 0.000 description 1
• 229940116362 tragacanth Drugs 0.000 description 1
• UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1