NO307865B1 - Use of carbazolyl (4) -oxypropylamine compounds for the preparation of a pharmaceutical composition for inhibiting the proliferation and migration of smooth muscle cells in mammals - Google Patents

Use of carbazolyl (4) -oxypropylamine compounds for the preparation of a pharmaceutical composition for inhibiting the proliferation and migration of smooth muscle cells in mammals

Info

Publication number
NO307865B1
NO307865B1 NO953480A NO953480A NO307865B1 NO 307865 B1 NO307865 B1 NO 307865B1 NO 953480 A NO953480 A NO 953480A NO 953480 A NO953480 A NO 953480A NO 307865 B1 NO307865 B1 NO 307865B1
Authority
NO
Norway
Prior art keywords
oxypropylamine
carbazolyl
mammals
proliferation
migration
Prior art date
Application number
NO953480A
Other languages
Norwegian (no)
Other versions
NO953480D0 (en
NO953480L (en
Inventor
Eliot H Ohlstein
Original Assignee
Boehringer Mannheim Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/026,892 external-priority patent/US5308862A/en
Application filed by Boehringer Mannheim Pharm Corp filed Critical Boehringer Mannheim Pharm Corp
Publication of NO953480D0 publication Critical patent/NO953480D0/en
Publication of NO953480L publication Critical patent/NO953480L/en
Publication of NO307865B1 publication Critical patent/NO307865B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
NO953480A 1993-03-05 1995-09-04 Use of carbazolyl (4) -oxypropylamine compounds for the preparation of a pharmaceutical composition for inhibiting the proliferation and migration of smooth muscle cells in mammals NO307865B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US1993/002062 WO1994020096A1 (en) 1993-03-05 1993-03-05 Method of employing carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
US08/026,892 US5308862A (en) 1993-03-05 1993-03-05 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
PCT/US1993/008019 WO1994020097A1 (en) 1993-03-05 1993-08-27 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation

Publications (3)

Publication Number Publication Date
NO953480D0 NO953480D0 (en) 1995-09-04
NO953480L NO953480L (en) 1995-11-03
NO307865B1 true NO307865B1 (en) 2000-06-13

Family

ID=26701782

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953480A NO307865B1 (en) 1993-03-05 1995-09-04 Use of carbazolyl (4) -oxypropylamine compounds for the preparation of a pharmaceutical composition for inhibiting the proliferation and migration of smooth muscle cells in mammals

Country Status (7)

Country Link
EP (1) EP0746315A4 (en)
JP (1) JPH08508013A (en)
AU (1) AU679462B2 (en)
NO (1) NO307865B1 (en)
RU (1) RU2147433C1 (en)
UA (1) UA41915C2 (en)
WO (2) WO1994020096A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (en) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh NEW CARBAZOLYL- (4) -OXY-PROPANOLAMINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3319027A1 (en) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD FOR PRODUCING OPTICALLY ACTIVE CARBAZOL DERIVATIVES, NEW R- AND S-CARBAZOL DERIVATIVES, AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
US4970227A (en) * 1984-11-20 1990-11-13 Burroughs Wellcome Co. Carbazole derivatives

Also Published As

Publication number Publication date
RU2147433C1 (en) 2000-04-20
EP0746315A1 (en) 1996-12-11
NO953480D0 (en) 1995-09-04
AU5092393A (en) 1994-09-26
AU679462B2 (en) 1997-07-03
NO953480L (en) 1995-11-03
EP0746315A4 (en) 1999-01-07
JPH08508013A (en) 1996-08-27
UA41915C2 (en) 2001-10-15
WO1994020096A1 (en) 1994-09-15
WO1994020097A1 (en) 1994-09-15

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