NO305436B1 - 8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation a - Google Patents

8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation a

Info

Publication number
NO305436B1
NO305436B1 NO944487A NO944487A NO305436B1 NO 305436 B1 NO305436 B1 NO 305436B1 NO 944487 A NO944487 A NO 944487A NO 944487 A NO944487 A NO 944487A NO 305436 B1 NO305436 B1 NO 305436B1
Authority
NO
Norway
Prior art keywords
methyl
preparation
piperidylidene
cyclohepta
benzo
Prior art date
Application number
NO944487A
Other languages
Norwegian (no)
Other versions
NO944487L (en
NO944487D0 (en
Inventor
Elena Carceller
N Ria Recasens
Carmen Almansa
Javier Bartroly
Manel Merlos
Marta Giral
Julian Garcia-Rafanell
Javier Forn
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Publication of NO944487D0 publication Critical patent/NO944487D0/en
Publication of NO944487L publication Critical patent/NO944487L/en
Publication of NO305436B1 publication Critical patent/NO305436B1/en

Links

NO944487A 1993-11-24 1994-11-23 8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation a NO305436B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09302460A ES2087818B1 (en) 1993-11-24 1993-11-24 8-CHLORINE-11- (1 - ((5-METHYL-3-PIRIDYL) METHYL) -4-PIPERIDYLIDEN) -6,11-DIHYDRO-5H-BENZO- (5,6) CYCLOHEPTAL (1,2-B) PIRIDINE, SMOKING.

Publications (3)

Publication Number Publication Date
NO944487D0 NO944487D0 (en) 1994-11-23
NO944487L NO944487L (en) 1995-05-26
NO305436B1 true NO305436B1 (en) 1999-05-31

Family

ID=8283716

Family Applications (2)

Application Number Title Priority Date Filing Date
NO944487A NO305436B1 (en) 1993-11-24 1994-11-23 8-chloro-11- [1 - [(5-methyl-3-pyridyl) methyl] -4-piperidylidene] -6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b] pyridine fumarate, method of preparation thereof, pharmaceutical composition comprising it, and use of the compound for preparation a
NO2014001C NO2014001I2 (en) 1993-11-24 2014-01-23 Rupatadine fumarate

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2014001C NO2014001I2 (en) 1993-11-24 2014-01-23 Rupatadine fumarate

Country Status (2)

Country Link
ES (1) ES2087818B1 (en)
NO (2) NO305436B1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2120899B1 (en) * 1996-10-07 1999-06-16 Uriach & Cia Sa J PROCEDURE FOR THE PREPARATION OF 8-CHLORO-6, 11-DIHYDRO-11- (1- (5-METHYL-3-PIRIDINYL) METHYL) -4-PIPERIDINYLIDENE) -5H-BENZO (5,6) CYCLOHEPTA (1, 2-B) PIRIDINE.
WO2006114676A2 (en) * 2005-04-27 2006-11-02 Cadila Pharmaceuticals Limited A process for the preparation of rupatadine
CN101531654B (en) * 2009-04-13 2013-07-17 浙江赐富医药有限公司 Preparation method for Rupatadine
JP5475929B2 (en) 2010-06-30 2014-04-16 ホタ． ウリアチ イ コンパニア ソシエダッド アノニマ Lupatadine fumarate solution
PL2588472T3 (en) * 2010-06-30 2014-09-30 J Uriach Y Compania S A RUPATADINE derivative AS AN ANTIHISTAMINIC AGENT
CN102807562A (en) * 2012-07-31 2012-12-05 东莞达信生物技术有限公司 Method for preparing rupatadine and salt thereof
CN103804357B (en) * 2014-01-02 2016-03-23 珠海金鸿药业股份有限公司 A kind of Rupatadine fumarate compound, its synthetic method and pharmaceutical composition thereof
CN109734702B (en) * 2019-03-01 2020-07-03 南京工业大学 Method for preparing rupatadine fumarate by adopting micro-channel reaction device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
US4826853A (en) * 1986-10-31 1989-05-02 Schering Corporation 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use
ZA914764B (en) * 1990-06-22 1992-03-25 Schering Corp Bis-benzo or benzopyrido cyclohepta piperidene,piperidylidene and piperazine compounds,compositions and methods of use
ES2042421B1 (en) * 1992-05-22 1994-08-01 Uriach & Cia Sa J PROCEDURE FOR OBTAINING 8-CHLORINE-11- * 1 - * (5-METHYL-3-PIRIDIL) METHYL * -4-PIPERIDILIDEN * -6,11-DIHYDRO-5H-BENZO * 5,6 * CYCLOHEPTA * 1 , 2-B * PIRIDINE.

Also Published As

Publication number Publication date
ES2087818B1 (en) 1997-03-16
NO944487L (en) 1995-05-26
NO2014001I2 (en) 2015-08-24
ES2087818A1 (en) 1996-07-16
NO944487D0 (en) 1994-11-23
NO2014001I1 (en) 2014-06-02

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: J URIACH Y COMPANIA SA, ES

MK1K Patent expired
SPCG Granted supplementary protection certificate

Free format text: PRODUCT NAME: RUPAFIN, 10 MG TABLETTER; REG.NO/DATE: 13-9499 2013.10.21; FIRST REG.NO/DATE: 16630 2001.07.04

Spc suppl protection certif: 2014001

Filing date: 20140123

Extension date: 20160704