NO2718426T3 - - Google Patents

Info

Publication number
NO2718426T3
NO2718426T3 NO12732995A NO12732995A NO2718426T3 NO 2718426 T3 NO2718426 T3 NO 2718426T3 NO 12732995 A NO12732995 A NO 12732995A NO 12732995 A NO12732995 A NO 12732995A NO 2718426 T3 NO2718426 T3 NO 2718426T3
Authority
NO
Norway
Application number
NO12732995A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2718426T3 publication Critical patent/NO2718426T3/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464452—Transcription factors, e.g. SOX or c-MYC
    • A61K39/464453—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464454—Enzymes
    • A61K39/464456—Tyrosinase or tyrosinase related proteinases [TRP-1 or TRP-2]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464484—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/464486—MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2307—Interleukin-7 (IL-7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
NO12732995A 2011-06-11 2012-06-11 NO2718426T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP11169655 2011-06-11
EP11177524A EP2532740A1 (en) 2011-06-11 2011-08-12 Antigen-specific CD4+ and CD8+ central-memory T cell preparations for adoptive T cell therapy
PCT/EP2012/061041 WO2012171882A1 (en) 2011-06-11 2012-06-11 Antigen-specific central-memory t cell preparations having high cd4+ fraction
EP12732995.1A EP2718426B1 (en) 2011-06-11 2012-06-11 Antigen-specific central-memory t cell preparations having high cd4+ fraction

Publications (1)

Publication Number Publication Date
NO2718426T3 true NO2718426T3 (en) 2018-04-21

Family

ID=45998693

Family Applications (1)

Application Number Title Priority Date Filing Date
NO12732995A NO2718426T3 (en) 2011-06-11 2012-06-11

Country Status (7)

Country Link
US (1) US9763985B2 (en)
EP (2) EP2532740A1 (en)
DE (1) DE112012002430T5 (en)
DK (1) DK2718426T3 (en)
ES (1) ES2659756T3 (en)
NO (1) NO2718426T3 (en)
WO (1) WO2012171882A1 (en)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10426740B1 (en) 2010-08-18 2019-10-01 Avm Biotechnology, Llc Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
JP2017528433A (en) * 2014-07-21 2017-09-28 ノバルティス アーゲー Low immunoenhancing dose of mTOR inhibitor and CAR combination
BR112017005631A2 (en) * 2014-09-19 2018-06-26 City Of Hope il13ra2-targeted chimeric costimulator antigen receptor t cells
KR20230148387A (en) 2015-05-28 2023-10-24 카이트 파마 인코포레이티드 Diagnostic methods for t cell therapy
IL305621A (en) 2015-05-28 2023-11-01 Us Health Methods of conditioning patients for t cell therapy
SG11201802966TA (en) 2015-10-20 2018-05-30 Kite Pharma Inc Methods of preparing t cells for t cell therapy
WO2017173384A1 (en) 2016-04-01 2017-10-05 Kite Pharma, Inc. Chimeric receptors and methods of use thereof
SI3436079T1 (en) 2016-04-01 2022-01-31 Kite Pharma, Inc. Chimeric antigen and t cell receptors and methods of use
CN109414455B (en) 2016-04-01 2023-01-20 凯德药业股份有限公司 BCMA binding molecules and methods of use thereof
AU2018219862B2 (en) 2017-02-07 2020-09-17 Nant Holding IP, LLC Maximizing T-cell memory and compositions and methods therefor
US11046775B2 (en) 2017-02-14 2021-06-29 Kite Pharma, Inc. CD70 binding molecules and methods of use thereof
WO2018169922A2 (en) 2017-03-13 2018-09-20 Kite Pharma, Inc. Chimeric antigen receptors for melanoma and uses thereof
MX2019011679A (en) 2017-04-01 2019-11-01 Avm Biotechnology Llc Replacement of cytotoxic preconditioning before cellular immunotherapy.
CA3057880A1 (en) 2017-04-03 2018-10-11 Kite Pharma, Inc. Treatment using chimeric receptor t cells incorporating optimized polyfunctional t cells
JOP20180042A1 (en) 2017-04-24 2019-01-30 Kite Pharma Inc Humanized Antigen-Binding Domains and Methods of Use
KR20230143631A (en) 2017-05-26 2023-10-12 카이트 파마 인코포레이티드 Methods of making and using embryonic mesenchymal progenitor cells
KR20230052312A (en) 2017-09-15 2023-04-19 카이트 파마 인코포레이티드 Methods and systems for performing a patient-specific immunotherapy procedure with chain-of-custody and chain-of-identity biological sample tracking
SG11202002533QA (en) 2017-09-22 2020-04-29 Kite Pharma Inc Chimeric polypeptides and uses thereof
KR20230011487A (en) 2017-10-18 2023-01-20 카이트 파마 인코포레이티드 Methods of administering chimeric antigen receptor immunotherapy
WO2019099707A1 (en) 2017-11-16 2019-05-23 Kite Pharma, Inc Modified chimeric antigen receptors and methods of use
CN111867680A (en) 2018-01-15 2020-10-30 辉瑞大药厂 Methods of administering chimeric antigen receptor immunotherapy in combination with 4-1BB agonists
US20200390814A1 (en) 2018-02-02 2020-12-17 Arizona Board Of Regents On Behalf Of Arizona State University Dna-chimeric antigen receptor t cells for immunotherapy
JP2021513839A (en) 2018-02-16 2021-06-03 カイト ファーマ インコーポレイテッドＫｉｔｅ Ｐｈａｒｍａ， Ｉｎｃ Modified pluripotent stem cells and manufacturing method and usage method
IL310416A (en) 2018-04-12 2024-03-01 Kite Pharma Inc Chimeric receptor t cell treatment using characteristics of the tumor microenvironment
WO2019232510A1 (en) 2018-06-01 2019-12-05 Kite Pharma, Inc. Chimeric antigen receptor t cell therapy
US20210155941A1 (en) 2018-06-22 2021-05-27 Kite Pharma Eu B.V. Compositions and methods for making engineered t cells
EP3830125A1 (en) 2018-08-02 2021-06-09 Kite Pharma, Inc. Chimeric antigen receptor therapy t cell expansion kinetics and uses thereof
EP3488851A1 (en) 2018-10-03 2019-05-29 AVM Biotechnology, LLC Immunoablative therapies
EP3632446B3 (en) 2018-10-03 2024-01-24 AVM Biotechnology, LLC Immunoablative therapies
MX2021005372A (en) 2018-11-08 2021-09-14 Neximmune Inc T cell compositions with improved phenotypic properties.
WO2020102701A1 (en) * 2018-11-16 2020-05-22 Rapa Therapeutics, Llc Methods for the manufacture of th1/tc1 phenotype t cells
WO2020102708A1 (en) 2018-11-16 2020-05-22 Rapa Therapeutics, Llc Methods for treating cancer with manufactured t cells
WO2020102715A1 (en) * 2018-11-16 2020-05-22 Rapa Therapeutics, Llc Method for t cell de-differentiation and resulting cells
BR112021012172A2 (en) 2018-12-12 2021-08-31 Kite Pharma, Inc. CHIMERIC AND T-CELL ANTIGEN RECEPTORS AND METHODS OF USE
US20200384027A1 (en) 2019-05-03 2020-12-10 Kite Pharma, Inc. Methods of administering chimeric antigen receptor immunotherapy
EP3976068A4 (en) * 2019-05-31 2023-08-09 Children's National Medical Center Cytokine cocktails for selective expansion of t cell subsets
JP2022536975A (en) 2019-06-21 2022-08-22 カイト ファーマ インコーポレイテッド TGF-β RECEPTOR AND METHOD OF USE
US11160832B2 (en) 2019-07-09 2021-11-02 The Children's Mercy Hospital Engineered regulatory T cells
KR20220054383A (en) 2019-09-03 2022-05-02 알로젠 테라퓨틱스 인코포레이티드 Methods of making T cells for T cell therapy
US20230293530A1 (en) 2020-06-24 2023-09-21 Yeda Research And Development Co. Ltd. Agents for sensitizing solid tumors to treatment
EP3957720A1 (en) 2020-08-21 2022-02-23 Charité - Universitätsmedizin Berlin Immunosuppressant-resistant t-cells for adoptive immunotherapy
CA3191161A1 (en) 2020-08-14 2022-02-17 Kite Pharma, Inc Improving immune cell function
EP4204545A2 (en) 2020-08-25 2023-07-05 Kite Pharma, Inc. T cells with improved functionality
WO2022093925A1 (en) 2020-10-28 2022-05-05 Kite Pharma, Inc. Flow cytometric method for characterization of t-cell impurities
AU2021410635A1 (en) 2020-12-24 2023-06-29 Kite Pharma, Inc. Prostate cancer chimeric antigen receptors
CA3207182A1 (en) 2021-01-10 2022-07-14 Kite Pharma, Inc. T cell therapy
TW202241469A (en) 2021-02-20 2022-11-01 美商凱特製藥公司 Immunotherapies
WO2022192439A1 (en) 2021-03-11 2022-09-15 Kite Pharma, Inc. Improving immune cell function
US20220336087A1 (en) 2021-04-16 2022-10-20 Kite Pharma, Inc. Methods and systems for scheduling a patient-specific immunotherapy procedure
IL307384A (en) 2021-04-16 2023-11-01 Kite Pharma Inc Taci/bcma dual binding molecules
IL308227A (en) 2021-05-14 2024-01-01 Kite Pharma Inc Chimeric antigen receptor t cell therapy
WO2022251120A2 (en) 2021-05-24 2022-12-01 Kite Pharma, Inc. Chimeric antigen receptor
CN117730100A (en) 2021-06-08 2024-03-19 凯德药业股份有限公司 GPC3 binding molecules
WO2023278553A1 (en) 2021-07-01 2023-01-05 Kite Pharma, Inc. Closed-system and method for autologous and allogeneic cell therapy manufacturing
WO2023278619A1 (en) 2021-07-02 2023-01-05 Kite Pharma, Inc. A method for identifying variants in gene products from gene constructs used in cell therapy applications
US20230060292A1 (en) 2021-07-26 2023-03-02 Kite Pharma, Inc. Split chimeric antigen receptors and methods of use
WO2023010114A1 (en) 2021-07-30 2023-02-02 Kite Pharma, Inc. Monitoring and management of cell therapy-induced toxicities
CA3232254A1 (en) 2021-10-18 2023-04-27 Kite Pharma, Inc. Signaling domains for chimeric antigen receptors
US20230296610A1 (en) 2022-02-15 2023-09-21 Kite Pharma, Inc. Predicting adverse events from immunotherapy
US20240091261A1 (en) 2022-08-26 2024-03-21 Kite Pharma, Inc. Immune cell function

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US551413A (en) 1895-12-17 Willakd b
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US4316885A (en) 1980-08-25 1982-02-23 Ayerst, Mckenna And Harrison, Inc. Acyl derivatives of rapamycin
US4650803A (en) 1985-12-06 1987-03-17 University Of Kansas Prodrugs of rapamycin
US5023264A (en) 1990-07-16 1991-06-11 American Home Products Corporation Rapamycin oximes
US5023263A (en) 1990-08-09 1991-06-11 American Home Products Corporation 42-oxorapamycin
US5130307A (en) 1990-09-28 1992-07-14 American Home Products Corporation Aminoesters of rapamycin
US5221670A (en) 1990-09-19 1993-06-22 American Home Products Corporation Rapamycin esters
US5233036A (en) 1990-10-16 1993-08-03 American Home Products Corporation Rapamycin alkoxyesters
US5120842A (en) 1991-04-01 1992-06-09 American Home Products Corporation Silyl ethers of rapamycin
US5100883A (en) 1991-04-08 1992-03-31 American Home Products Corporation Fluorinated esters of rapamycin
US5118678A (en) 1991-04-17 1992-06-02 American Home Products Corporation Carbamates of rapamycin
US5118677A (en) 1991-05-20 1992-06-02 American Home Products Corporation Amide esters of rapamycin
US5162333A (en) 1991-09-11 1992-11-10 American Home Products Corporation Aminodiesters of rapamycin
US5177203A (en) 1992-03-05 1993-01-05 American Home Products Corporation Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents
US5256790A (en) 1992-08-13 1993-10-26 American Home Products Corporation 27-hydroxyrapamycin and derivatives thereof
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
JP3210095B2 (en) 1992-10-13 2001-09-17 ハッコールケミカル株式会社 Organic white pigment
US5302584A (en) 1992-10-13 1994-04-12 American Home Products Corporation Carbamates of rapamycin
US5489680A (en) 1992-10-13 1996-02-06 American Home Products Corporation Carbamates of rapamycin
US5480989A (en) 1992-10-13 1996-01-02 American Home Products Corporation Carbamates of rapamycin
US5434260A (en) 1992-10-13 1995-07-18 American Home Products Corporation Carbamates of rapamycin
US5480988A (en) 1992-10-13 1996-01-02 American Home Products Corporation Carbamates of rapamycin
US5411967A (en) 1992-10-13 1995-05-02 American Home Products Corporation Carbamates of rapamycin
US5262423A (en) 1992-10-29 1993-11-16 American Home Products Corporation Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents
US5258389A (en) 1992-11-09 1993-11-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
US5260300A (en) 1992-11-19 1993-11-09 American Home Products Corporation Rapamycin carbonate esters as immuno-suppressant agents
US5504091A (en) 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
US5378836A (en) 1993-10-08 1995-01-03 American Home Products Corporation Rapamycin oximes and hydrazones
US5391730A (en) 1993-10-08 1995-02-21 American Home Products Corporation Phosphorylcarbamates of rapamycin and oxime derivatives thereof
US5373014A (en) 1993-10-08 1994-12-13 American Home Products Corporation Rapamycin oximes
US5385910A (en) 1993-11-22 1995-01-31 American Home Products Corporation Gem-distributed esters of rapamycin
US5385909A (en) 1993-11-22 1995-01-31 American Home Products Corporation Heterocyclic esters of rapamycin
US5385908A (en) 1993-11-22 1995-01-31 American Home Products Corporation Hindered esters of rapamycin
US5389639A (en) 1993-12-29 1995-02-14 American Home Products Company Amino alkanoic esters of rapamycin
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US5463048A (en) 1994-06-14 1995-10-31 American Home Products Corporation Rapamycin amidino carbamates
US5491231A (en) 1994-11-28 1996-02-13 American Home Products Corporation Hindered N-oxide esters of rapamycin
US5563145A (en) 1994-12-07 1996-10-08 American Home Products Corporation Rapamycin 42-oximes and hydroxylamines
US5780462A (en) 1995-12-27 1998-07-14 American Home Products Corporation Water soluble rapamycin esters
DE10009341A1 (en) 2000-02-22 2001-09-06 Florian Kern Method for antigen-specific stimulation of T lymphocytes
US20100254958A1 (en) 2007-10-24 2010-10-07 Anne Letsch Antigen-Specific T-Cell Preparations from Bone Marrow
US9057054B2 (en) * 2009-06-25 2015-06-16 The Regents Of The University Of Michigan Antigen-specific long-term memory T-cells

Also Published As

Publication number Publication date
WO2012171882A1 (en) 2012-12-20
EP2532740A1 (en) 2012-12-12
ES2659756T3 (en) 2018-03-19
DK2718426T3 (en) 2018-02-26
EP2718426A1 (en) 2014-04-16
DE112012002430T5 (en) 2014-03-06
EP2718426B1 (en) 2017-11-22
US20140154228A1 (en) 2014-06-05
US9763985B2 (en) 2017-09-19

Similar Documents

Publication Publication Date Title
BR112013022641A2 (en)
AP3853A (en)
BR112013031251A2 (en)
NO2718426T3 (en)
BR112013024383A2 (en)
BR112013026905A2 (en)
BR112013023185A2 (en)
BR112013022995A2 (en)
BR112013017670A2 (en)
BR112013026744A2 (en)
BR112013023927A2 (en)
BR112013024365A2 (en)
BR112013028733A2 (en)
BR112013027121A2 (en)
AP2016009466A0 (en)
BR112013031556A2 (en)
BR112013024588A2 (en)
BR112013032377A2 (en)
BR112013032380A2 (en)
BR112013032368A2 (en)
BR112013018949A2 (en)
BR112013027836A2 (en)
BR112013023266A2 (en)
BR112013032392A2 (en)
BR112013025487A2 (en)