NO2665471T3 - - Google Patents
Info
- Publication number
- NO2665471T3 NO2665471T3 NO12736469A NO12736469A NO2665471T3 NO 2665471 T3 NO2665471 T3 NO 2665471T3 NO 12736469 A NO12736469 A NO 12736469A NO 12736469 A NO12736469 A NO 12736469A NO 2665471 T3 NO2665471 T3 NO 2665471T3
- Authority
- NO
- Norway
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/13—Amines containing three or more amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/12—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms
- C07C243/16—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
- C07C251/12—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton being acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/78—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161434269P | 2011-01-19 | 2011-01-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2665471T3 true NO2665471T3 (fr) | 2018-05-26 |
Family
ID=46516367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO12736469A NO2665471T3 (fr) | 2011-01-19 | 2012-01-19 |
Country Status (10)
Country | Link |
---|---|
US (4) | US8858991B2 (fr) |
EP (1) | EP2665471B1 (fr) |
CA (1) | CA2825014C (fr) |
DK (1) | DK2665471T3 (fr) |
ES (1) | ES2662373T3 (fr) |
HU (1) | HUE038543T2 (fr) |
NO (1) | NO2665471T3 (fr) |
PL (1) | PL2665471T3 (fr) |
PT (1) | PT2665471T (fr) |
WO (1) | WO2012100043A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2627676T3 (es) | 2007-03-09 | 2017-07-31 | Pathologica Llc | MGBG para la regulación de osteopontina y el tratamiento de la esclerosis múltiple |
NZ628513A (en) | 2009-07-16 | 2016-01-29 | Pathologica Llc | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
US9675566B2 (en) * | 2009-07-16 | 2017-06-13 | Pathologica Llc | Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing |
EP2665471B1 (fr) | 2011-01-19 | 2017-12-27 | Pathologica, LLC. | Formes posologiques pharmaceutiques orales à libération contrôlée comprenant de la mgbg |
CN105163730B (zh) | 2013-01-08 | 2018-10-30 | 帕萨罗杰卡有限公司 | 用于治疗脱髓鞘疾病的方法和组合物 |
US10987368B2 (en) * | 2014-12-08 | 2021-04-27 | Glycom A/S | Synthetic composition for preventing or treating CVD |
US10881674B2 (en) | 2014-12-08 | 2021-01-05 | Glycom A/S | Synthetic composition for treating metabolic disorders |
SG11202107145SA (en) | 2019-01-25 | 2021-08-30 | Univ Brown | Compositions and methods for treating, preventing or reversing age-associated inflammation and disorders |
Family Cites Families (47)
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US4201788A (en) | 1976-10-20 | 1980-05-06 | University Patents, Inc. | Process for alleviating proliferative skin diseases |
US5614557A (en) | 1977-07-11 | 1997-03-25 | Marion Merrell Et Compagnie C/O Merrell Pharmaceuticals Inc. | Method of controlling tumor growth rate |
US4520031A (en) * | 1981-06-01 | 1985-05-28 | The United States Of America As Represented By The Secretary Of Department Of Health And Human Services | Method for reducing toxic effects of methyl-glyoxal bis-guanylhydrazone |
CA1338366C (fr) | 1984-12-26 | 1996-06-04 | Algis Anilionis | Systeme d'expression procaryotique d'une grande efficacite |
US5580715A (en) | 1994-08-05 | 1996-12-03 | The Regents Of The University Of California | Diagnosis of cancer having clonal macrophage involvement |
US5639600A (en) | 1994-08-05 | 1997-06-17 | The Regents Of The University Of California | Diagnosis and treatment of cell proliferative disease having clonal macrophage involvement |
US5698563A (en) | 1995-01-13 | 1997-12-16 | Alteon Inc. | Bis- hydrazones! |
US8198334B2 (en) | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
US7087648B1 (en) | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
US6169115B1 (en) | 1998-05-22 | 2001-01-02 | Rima Kaddurah-Daouk | Use of aminoguanidine analogs for the treatment of diseases of the nervous system |
US6544541B1 (en) | 1999-06-02 | 2003-04-08 | Cardiovascular Solutions, Inc. | Devices and compounds for treating arterial restenosis |
WO2001060392A1 (fr) | 2000-02-18 | 2001-08-23 | Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science | Formes posologiques a administration par voie orale, nasale et pulmonaire du copolymere 1 |
US7754765B2 (en) | 2000-12-01 | 2010-07-13 | Radical Vision Therapeutics Inc | Copper chelators for treating ocular inflammation |
US6991809B2 (en) * | 2001-06-23 | 2006-01-31 | Lyotropic Therapeutics, Inc. | Particles with improved solubilization capacity |
US20040219208A1 (en) * | 2001-08-03 | 2004-11-04 | Ryu Kawamura | Sustained-release medicines |
WO2003016491A2 (fr) | 2001-08-15 | 2003-02-27 | The Regents Of The University Of California | Retrovirus isole a partir d'histiocytes de cellules du manteau |
US7030126B2 (en) | 2001-11-16 | 2006-04-18 | Als Therapy Development Foundation, Inc. | Use of polyamine analogs for amyotrophic lateral sclerosis |
US7622117B2 (en) | 2002-04-17 | 2009-11-24 | Dynamis Therapeutics, Inc. | 3-deoxyglucosone and skin |
EP1389480A1 (fr) | 2002-08-14 | 2004-02-18 | Mondobiotech Interferon SA | Utilisation thérapeutique de guanylhydrazones pour l'inhibition des procédés dépendant du CD83 et de la maturation des cellules dendritiques |
EP1613263A4 (fr) | 2003-01-31 | 2007-11-28 | Pathologica Llc | Suivi et de traitement de la sclerose laterale amyotrophique |
US20060177506A1 (en) * | 2003-03-17 | 2006-08-10 | Shigeo Yanai | Release control compositions |
HUE028247T2 (en) | 2003-04-08 | 2016-12-28 | Novartis Ag | A solid oral composition comprising S1P receptor agonist and sugar alcohol |
RU2375048C2 (ru) * | 2003-07-17 | 2009-12-10 | Д-Р Редди'С Лабораторис Инк. | Фармацевтическая композиция с набухающим покрытием |
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US7445794B1 (en) * | 2004-04-29 | 2008-11-04 | The Regents Of The University Of Colorado | Methods for treating human proliferative diseases, with a combination of fatty acid metabolism inhibitors and glycolytic inhibitors |
KR20070110046A (ko) | 2005-01-28 | 2007-11-15 | 크산투스 파마슈티컬스, 인코포레이티드 | 염증 및 탈수초성 질환을 치료하기 위한 화합물 |
AU2006275679B2 (en) | 2005-07-29 | 2012-04-12 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of Chk2 kinase inhibitors for cancer treatment |
JP2009502908A (ja) * | 2005-07-29 | 2009-01-29 | スティッチング グロニンゲン セントル フォー ドラッグ リサーチ | pH制御パルス送達システム、その調製法及び使用法 |
CN101300004B (zh) | 2005-09-23 | 2013-08-21 | 帕瑟洛吉卡有限公司 | 使用多胺类似物治疗病毒感染的方法 |
US20070202515A1 (en) * | 2005-10-12 | 2007-08-30 | Pathologica, Llc. | Promac signature application |
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EP2164698A1 (fr) | 2007-03-09 | 2010-03-24 | Sustainable Solutions, Inc. | Matériau de panneau en coton régénéré et procédé de fabrication |
ES2627676T3 (es) | 2007-03-09 | 2017-07-31 | Pathologica Llc | MGBG para la regulación de osteopontina y el tratamiento de la esclerosis múltiple |
NZ580972A (en) * | 2007-06-04 | 2012-02-24 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
WO2009018368A1 (fr) | 2007-07-30 | 2009-02-05 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Traitement d'association à base d'amplificateur du nmda (n-méthyl-d-aspartate), d'inhibiteur de transporteur de glycine, d'inhibiteur de d-amino acide oxydase pour des troubles neuropsychiatriques |
US20110318380A1 (en) | 2008-10-01 | 2011-12-29 | Dako Denmark A/S | MHC Multimers in Cancer Vaccines and Immune Monitoring |
JP2012505257A (ja) | 2008-10-13 | 2012-03-01 | バイオヴィスタ,インコーポレイテッド | 多発性硬化症治療のための組成物および方法 |
WO2010066203A1 (fr) * | 2008-12-10 | 2010-06-17 | Anhui Zhongren Technology Co., Ltd. | Composition à libération contrôlée |
US20100189791A1 (en) | 2009-01-23 | 2010-07-29 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline malate formulation |
US9675566B2 (en) | 2009-07-16 | 2017-06-13 | Pathologica Llc | Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing |
NZ628513A (en) | 2009-07-16 | 2016-01-29 | Pathologica Llc | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
EP2283830A1 (fr) * | 2009-07-23 | 2011-02-16 | Actogenix N.V. | Revêtement de capsule entérique aqueuse |
EP2343075A1 (fr) | 2010-01-04 | 2011-07-13 | Neurotec Pharma, S.L. | Diazoxyde à utiliser dans le traitement d'une maladie de démyélinisation auto-immune du système nerveux central (SNC) |
TWI590821B (zh) * | 2011-01-18 | 2017-07-11 | 輝瑞有限公司 | 固體分子分散液 |
EP2665471B1 (fr) | 2011-01-19 | 2017-12-27 | Pathologica, LLC. | Formes posologiques pharmaceutiques orales à libération contrôlée comprenant de la mgbg |
CN105163730B (zh) | 2013-01-08 | 2018-10-30 | 帕萨罗杰卡有限公司 | 用于治疗脱髓鞘疾病的方法和组合物 |
-
2012
- 2012-01-19 EP EP12736469.3A patent/EP2665471B1/fr active Active
- 2012-01-19 DK DK12736469.3T patent/DK2665471T3/en active
- 2012-01-19 CA CA2825014A patent/CA2825014C/fr active Active
- 2012-01-19 ES ES12736469.3T patent/ES2662373T3/es active Active
- 2012-01-19 NO NO12736469A patent/NO2665471T3/no unknown
- 2012-01-19 HU HUE12736469A patent/HUE038543T2/hu unknown
- 2012-01-19 WO PCT/US2012/021853 patent/WO2012100043A2/fr active Application Filing
- 2012-01-19 US US13/354,076 patent/US8858991B2/en active Active
- 2012-01-19 PT PT127364693T patent/PT2665471T/pt unknown
- 2012-01-19 PL PL12736469T patent/PL2665471T3/pl unknown
-
2014
- 2014-09-09 US US14/480,847 patent/US9668988B2/en active Active
-
2017
- 2017-05-01 US US15/583,697 patent/US10881626B2/en active Active
-
2020
- 2020-12-04 US US17/111,895 patent/US20210085625A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HUE038543T2 (hu) | 2018-10-29 |
CA2825014A1 (fr) | 2012-07-26 |
US10881626B2 (en) | 2021-01-05 |
CA2825014C (fr) | 2019-01-08 |
US20120269891A1 (en) | 2012-10-25 |
PT2665471T (pt) | 2018-03-21 |
US9668988B2 (en) | 2017-06-06 |
ES2662373T3 (es) | 2018-04-06 |
PL2665471T3 (pl) | 2018-06-29 |
EP2665471B1 (fr) | 2017-12-27 |
US8858991B2 (en) | 2014-10-14 |
WO2012100043A2 (fr) | 2012-07-26 |
EP2665471A2 (fr) | 2013-11-27 |
WO2012100043A3 (fr) | 2012-10-18 |
DK2665471T3 (en) | 2018-03-19 |
EP2665471A4 (fr) | 2014-07-23 |
US20180050000A1 (en) | 2018-02-22 |
US20140377345A1 (en) | 2014-12-25 |
US20210085625A1 (en) | 2021-03-25 |