NO20084348L - Vaksine for terapeutiske eller profylaktisk behandling av myastenia gravis - Google Patents

Vaksine for terapeutiske eller profylaktisk behandling av myastenia gravis

Info

Publication number
NO20084348L
NO20084348L NO20084348A NO20084348A NO20084348L NO 20084348 L NO20084348 L NO 20084348L NO 20084348 A NO20084348 A NO 20084348A NO 20084348 A NO20084348 A NO 20084348A NO 20084348 L NO20084348 L NO 20084348L
Authority
NO
Norway
Prior art keywords
therapeutic
vaccine
prophylactic treatment
myastenia gravis
complementary
Prior art date
Application number
NO20084348A
Other languages
English (en)
Other versions
NO341727B1 (no
Inventor
Stephane P Huberty
Edwin J Blalock
Original Assignee
Curavac Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curavac Inc filed Critical Curavac Inc
Publication of NO20084348L publication Critical patent/NO20084348L/no
Publication of NO341727B1 publication Critical patent/NO341727B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Abstract

Det beskrives et komplementært peptid som har minst en sekvens komplementær til en hovedimmunogen region av en acetylkolin reseptor involvert i myastenia gravis, kjennetegnet ved at det komplementære peptidet har minst en sekvens SEQ. ID. NO 1 med en tryptofan i posisjon 8, som bærer minst en valgfritt substituert hydrokarbongruppe. Terapeutiske sammensetninger omfattende det komplementære peptid i samsvar med oppfinnelsen, og anvendelser derav for fremstilling av en vaksine som skal anvendes i en terapeutisk eller profylaktisk behandling av myastenia gravis i pattedyr.
NO20084348A 2006-03-23 2008-10-16 Vaksine for terapeutisk eller profylaktisk behandling av myastenia gravis NO341727B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/010896 WO2007108808A1 (en) 2006-03-23 2006-03-23 Vaccine for a therapeutic or a prophylactic treatment of myasthenia gravis

Publications (2)

Publication Number Publication Date
NO20084348L true NO20084348L (no) 2008-12-23
NO341727B1 NO341727B1 (no) 2018-01-08

Family

ID=38522753

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084348A NO341727B1 (no) 2006-03-23 2008-10-16 Vaksine for terapeutisk eller profylaktisk behandling av myastenia gravis

Country Status (12)

Country Link
US (2) US8691236B2 (no)
EP (1) EP2004217B1 (no)
JP (1) JP5052594B2 (no)
CN (1) CN101443035B (no)
AU (1) AU2006340368B2 (no)
BR (1) BRPI0621487B8 (no)
CA (1) CA2646004C (no)
ES (1) ES2534228T3 (no)
NO (1) NO341727B1 (no)
NZ (1) NZ572110A (no)
PL (1) PL2004217T3 (no)
WO (1) WO2007108808A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8592889B1 (en) * 2012-05-21 2013-11-26 United Microelectronics Corp. Memory structure
US11235040B2 (en) 2014-09-15 2022-02-01 The Trustees Of The University Of Pennsylvania Acetylcholine receptor-specific immunosuppressive compositions and methods of treatment of myasthenia gravis
BE1029149B1 (fr) 2021-02-26 2022-09-26 Nicolas Havelange Protéine porteuse pour antigene peptidique
BE1029148B1 (fr) 2021-02-26 2022-09-26 Curavac Europe Vaccin pour un traitement therapeutique ou prophylactique de la myastenie grave

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4833500A (en) * 1999-05-12 2000-12-05 Uab Research Foundation, The Antibody vaccine for autoimmune diseases

Also Published As

Publication number Publication date
JP5052594B2 (ja) 2012-10-17
BRPI0621487A2 (pt) 2011-12-13
NZ572110A (en) 2010-04-30
US20090117138A1 (en) 2009-05-07
CN101443035A (zh) 2009-05-27
WO2007108808A1 (en) 2007-09-27
BRPI0621487B8 (pt) 2021-05-25
US9359406B2 (en) 2016-06-07
ES2534228T3 (es) 2015-04-20
AU2006340368A8 (en) 2008-11-27
PL2004217T3 (pl) 2015-07-31
BRPI0621487B1 (pt) 2018-02-14
CA2646004C (en) 2016-05-10
EP2004217B1 (en) 2014-12-10
CA2646004A1 (en) 2007-09-27
NO341727B1 (no) 2018-01-08
US8691236B2 (en) 2014-04-08
AU2006340368B2 (en) 2013-03-14
EP2004217A1 (en) 2008-12-24
CN101443035B (zh) 2013-11-13
EP2004217A4 (en) 2010-06-09
AU2006340368A1 (en) 2007-09-27
US20140161831A1 (en) 2014-06-12
JP2009530375A (ja) 2009-08-27

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