NO20082503L - Fremgangsmate for fremstilling av olanzapin - Google Patents
Fremgangsmate for fremstilling av olanzapinInfo
- Publication number
- NO20082503L NO20082503L NO20082503A NO20082503A NO20082503L NO 20082503 L NO20082503 L NO 20082503L NO 20082503 A NO20082503 A NO 20082503A NO 20082503 A NO20082503 A NO 20082503A NO 20082503 L NO20082503 L NO 20082503L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- thieno
- methyl
- formula
- benzodiazepine
- Prior art date
Links
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229960005017 olanzapine Drugs 0.000 title abstract 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- CYSGHNMQYZDMIA-UHFFFAOYSA-N 1,3-Dimethyl-2-imidazolidinon Chemical compound CN1CCN(C)C1=O CYSGHNMQYZDMIA-UHFFFAOYSA-N 0.000 abstract 1
- PVOAHINGSUIXLS-UHFFFAOYSA-N 1-Methylpiperazine Chemical compound CN1CCNCC1 PVOAHINGSUIXLS-UHFFFAOYSA-N 0.000 abstract 1
- FDWMAKNNNPSUTL-UHFFFAOYSA-N 2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-amine hydrochloride Chemical compound Cl.N1C2=CC=CC=C2N=C(N)C2=C1SC(C)=C2 FDWMAKNNNPSUTL-UHFFFAOYSA-N 0.000 abstract 1
- MKJITEGSXPMAKU-UHFFFAOYSA-N 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine trihydrate dihydrochloride Chemical compound O.O.O.Cl.Cl.C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 MKJITEGSXPMAKU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0501046A HUP0501046A2 (en) | 2005-11-11 | 2005-11-11 | Process for the preparation of olanzapine |
| PCT/HU2006/000096 WO2007054750A2 (en) | 2005-11-11 | 2006-11-10 | Process for the preparation of olanzapine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082503L true NO20082503L (no) | 2008-08-11 |
Family
ID=89986394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082503A NO20082503L (no) | 2005-11-11 | 2008-06-03 | Fremgangsmate for fremstilling av olanzapin |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7981884B2 (de) |
| EP (2) | EP1997822A1 (de) |
| JP (1) | JP2009515867A (de) |
| CN (1) | CN101400683A (de) |
| AT (1) | ATE508131T1 (de) |
| DE (1) | DE602006021792D1 (de) |
| EA (2) | EA201001278A1 (de) |
| HU (1) | HUP0501046A2 (de) |
| NO (1) | NO20082503L (de) |
| PL (1) | PL1963335T3 (de) |
| SI (1) | SI1963335T1 (de) |
| UA (1) | UA93527C2 (de) |
| WO (1) | WO2007054750A2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102924472B (zh) * | 2012-09-03 | 2013-06-05 | 江苏豪森药业股份有限公司 | 一种奥氮平的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9009229D0 (en) * | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
| EG23659A (en) | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| US5631250A (en) | 1995-03-24 | 1997-05-20 | Eli Lilly And Company | Process and solvate of 2-methyl-thieno-benzodiazepine |
| EP1313742A1 (de) * | 2000-08-31 | 2003-05-28 | Dr. Reddy's Laboratories Ltd. | Verfahren zur herstellung von olanzapine-hydraten und deren umsetzungen in krystallinischen formen der olanzapine |
| ATE500258T1 (de) | 2002-05-31 | 2011-03-15 | Sandoz Ag | Verfahren zur herstellung von olanzapin form i |
| HU226410B1 (en) | 2003-04-22 | 2008-11-28 | Egis Gyogyszergyar Nyilvanosan | Novel polymorphous forms of olanzapine hydrochlorides, process for producing them, use thereof and pharmaceutical compositions containing them |
| PT1611139E (pt) * | 2003-12-22 | 2008-07-17 | Teva Pharma | Métodos de preparação de olanzapina |
-
2005
- 2005-11-11 HU HU0501046A patent/HUP0501046A2/hu unknown
-
2006
- 2006-11-10 EA EA201001278A patent/EA201001278A1/ru unknown
- 2006-11-10 EP EP08013602A patent/EP1997822A1/de not_active Withdrawn
- 2006-11-10 DE DE602006021792T patent/DE602006021792D1/de active Active
- 2006-11-10 SI SI200631072T patent/SI1963335T1/sl unknown
- 2006-11-10 UA UAA200807902A patent/UA93527C2/ru unknown
- 2006-11-10 EA EA200801043A patent/EA014934B1/ru not_active IP Right Cessation
- 2006-11-10 CN CNA2006800418177A patent/CN101400683A/zh active Pending
- 2006-11-10 EP EP06808805A patent/EP1963335B1/de active Active
- 2006-11-10 JP JP2008539513A patent/JP2009515867A/ja not_active Ceased
- 2006-11-10 WO PCT/HU2006/000096 patent/WO2007054750A2/en active Application Filing
- 2006-11-10 AT AT06808805T patent/ATE508131T1/de not_active IP Right Cessation
- 2006-11-10 US US12/093,344 patent/US7981884B2/en not_active Expired - Fee Related
- 2006-11-10 PL PL06808805T patent/PL1963335T3/pl unknown
-
2008
- 2008-06-03 NO NO20082503A patent/NO20082503L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| UA93527C2 (en) | 2011-02-25 |
| EP1963335B1 (de) | 2011-05-04 |
| CN101400683A (zh) | 2009-04-01 |
| US20090137563A1 (en) | 2009-05-28 |
| SI1963335T1 (sl) | 2011-10-28 |
| JP2009515867A (ja) | 2009-04-16 |
| HUP0501046A2 (en) | 2007-08-28 |
| PL1963335T3 (pl) | 2011-12-30 |
| EA014934B1 (ru) | 2011-04-29 |
| EP1963335A2 (de) | 2008-09-03 |
| HU0501046D0 (en) | 2006-01-30 |
| ATE508131T1 (de) | 2011-05-15 |
| EP1997822A1 (de) | 2008-12-03 |
| EA200801043A1 (ru) | 2008-10-30 |
| EA201001278A1 (ru) | 2011-02-28 |
| US7981884B2 (en) | 2011-07-19 |
| DE602006021792D1 (de) | 2011-06-16 |
| WO2007054750A3 (en) | 2007-10-11 |
| WO2007054750A2 (en) | 2007-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |