NO20081233L - Albumin fusion proteins - Google Patents
Albumin fusion proteinsInfo
- Publication number
- NO20081233L NO20081233L NO20081233A NO20081233A NO20081233L NO 20081233 L NO20081233 L NO 20081233L NO 20081233 A NO20081233 A NO 20081233A NO 20081233 A NO20081233 A NO 20081233A NO 20081233 L NO20081233 L NO 20081233L
- Authority
- NO
- Norway
- Prior art keywords
- albumin infusion
- proteins
- nucleic acids
- vectors
- fusion proteins
- Prior art date
Links
- 102000009027 Albumins Human genes 0.000 title abstract 6
- 108010088751 Albumins Proteins 0.000 title abstract 6
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 238000001802 infusion Methods 0.000 abstract 5
- 102000039446 nucleic acids Human genes 0.000 abstract 5
- 108020004707 nucleic acids Proteins 0.000 abstract 5
- 150000007523 nucleic acids Chemical class 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 239000013598 vector Substances 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Foreliggende oppfinnelse omfatter albuminfusjonsproteinet. Nukleinsyremolekylene kodende for albuminfusjonsproteinene av oppfinnelsen er også omsluttet av oppfinnelsen, det er er også vektorer inneholdende disse nukleinsyrene, vertsceller transformert med disse nukleinsyrevektorene og fremgangsmåter for å lage albuminfusjonsproteiner ifølge oppfinnelsen, og å benytte disse nukleinsyrene, vektorene og/eller vertscellene. I tillegg omslutter den foreliggende oppfinnelsen farmasøytiske sammensetninger omfattende albuminfusjonsproteiner og deres fremgangsmåter og behandling, forebygging eller forbedring av sykdommer, lidelser eller tilstander ved å benytte albuminfusjonsproteiner av oppfinnelsen.The present invention comprises the albumin infusion protein. The nucleic acid molecules encoding the albumin infusion proteins of the invention are also encompassed by the invention, there are also vectors containing these nucleic acids, host cells transformed with these nucleic acid vectors and methods of making albumin infusion proteins of the invention, and using these nucleic acids or vectors or nucleic acids. In addition, the present invention encompasses pharmaceutical compositions comprising albumin infusion proteins and their methods and treatment, prevention or amelioration of diseases, disorders or conditions utilizing albumin infusion proteins of the invention.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70752105P | 2005-08-12 | 2005-08-12 | |
US71238605P | 2005-08-31 | 2005-08-31 | |
US73272405P | 2005-11-03 | 2005-11-03 | |
US77691406P | 2006-02-28 | 2006-02-28 | |
US78136106P | 2006-03-13 | 2006-03-13 | |
US81018206P | 2006-06-02 | 2006-06-02 | |
US81368206P | 2006-06-15 | 2006-06-15 | |
PCT/US2006/029391 WO2007021494A2 (en) | 2005-08-12 | 2006-07-31 | Albumin fusion proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20081233L true NO20081233L (en) | 2008-05-09 |
Family
ID=37758042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081233A NO20081233L (en) | 2005-08-12 | 2008-03-10 | Albumin fusion proteins |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1924596A4 (en) |
JP (1) | JP2009504157A (en) |
KR (1) | KR20080071119A (en) |
AU (1) | AU2006280312A1 (en) |
BR (1) | BRPI0614761A2 (en) |
CA (1) | CA2618476A1 (en) |
EC (1) | ECSP088262A (en) |
IL (1) | IL189246A0 (en) |
MA (1) | MA29836B1 (en) |
MX (1) | MX2008001865A (en) |
NO (1) | NO20081233L (en) |
TN (1) | TNSN08064A1 (en) |
WO (1) | WO2007021494A2 (en) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
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GB9526733D0 (en) | 1995-12-30 | 1996-02-28 | Delta Biotechnology Ltd | Fusion proteins |
CA2405557C (en) | 2000-04-12 | 2013-09-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
ES2545090T3 (en) | 2001-12-21 | 2015-09-08 | Human Genome Sciences, Inc. | Albumin and GCSF fusion proteins |
US20080194481A1 (en) | 2001-12-21 | 2008-08-14 | Human Genome Sciences, Inc. | Albumin Fusion Proteins |
SI1729795T1 (en) | 2004-02-09 | 2016-04-29 | Human Genome Sciences, Inc. | Albumin fusion proteins |
EP1816201A1 (en) | 2006-02-06 | 2007-08-08 | CSL Behring GmbH | Modified coagulation factor VIIa with extended half-life |
EP2046367A4 (en) | 2006-06-07 | 2009-11-11 | Human Genome Sciences Inc | Albumin fusion proteins |
BRPI0716744A2 (en) * | 2006-09-14 | 2016-10-04 | Human Genome Sciences Inc | albumin fusion proteins |
CA2963138C (en) | 2007-01-30 | 2019-05-14 | Epivax, Inc. | Regulatory t cell epitopes, compositions and uses thereof |
EP2305309A2 (en) | 2008-06-13 | 2011-04-06 | Proyecto de Biomedicina Cima, S.L. | Conjugates for the administration of biologically active compounds |
KR20110132326A (en) | 2009-01-16 | 2011-12-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | New stable formulations of recombinant human albumin-human granulocyte colony stimulating factor fusion protein |
SG2014012918A (en) | 2009-02-11 | 2014-04-28 | Novozymes Biopharma Dk As | Albumin variants and conjugates |
KR20100100254A (en) * | 2009-03-05 | 2010-09-15 | (주)바이오큐어팜 | Composition for preventing or treating cancer comprising human serum albumin-timp-2 fusion protein and anti-cancer agent |
AU2010290131C1 (en) | 2009-08-24 | 2015-12-03 | Amunix Operating Inc. | Coagulation factor VII compositions and methods of making and using same |
CN105567699A (en) * | 2009-10-30 | 2016-05-11 | 诺维信生物制药丹麦公司 | Albumin variants |
WO2011124718A1 (en) | 2010-04-09 | 2011-10-13 | Novozymes A/S | Albumin derivatives and variants |
JP6200806B2 (en) | 2010-05-21 | 2017-09-20 | メリマック ファーマシューティカルズ インコーポレーティッド | Bispecific fusion protein |
WO2012118042A1 (en) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | Medicinal agent for inhibiting metastasis of malignant tumor |
CN104011072B (en) | 2011-05-05 | 2018-10-12 | 阿尔布梅迪克斯医疗有限公司 | albumin variants |
US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
PT2717898T (en) | 2011-06-10 | 2019-05-20 | Bioverativ Therapeutics Inc | Pro-coagulant compounds and methods of use thereof |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
SG2014011670A (en) | 2011-10-21 | 2014-10-30 | Abbvie Inc | Combination treatment (eg. with abt-072 or abt -333) of daas for use in treating hcv |
CN103826627B (en) | 2011-10-21 | 2016-02-24 | 艾伯维公司 | Comprise the purposes of compositions in the medicine of preparation treatment HCV of at least two kinds of direct antiviral agent and ribavirin |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
US20140315817A1 (en) | 2011-11-18 | 2014-10-23 | Eleven Biotherapeutics, Inc. | Variant serum albumin with improved half-life and other properties |
BR112014017165B1 (en) | 2012-01-12 | 2023-05-02 | Bioverativ Therapeutics Inc | CHIMERIC PROTEIN COMPRISING A FACTOR VIII PROTEIN, PHARMACEUTICAL COMPOSITION, AND USES THEREOF |
ES2771208T3 (en) | 2012-02-15 | 2020-07-06 | Bioverativ Therapeutics Inc | Factor VIII compositions and methods of preparation and use thereof |
DK2822577T3 (en) | 2012-02-15 | 2019-04-01 | Bioverativ Therapeutics Inc | RECOMBINANT FACTOR VIII PROTEINS |
EP3330283A3 (en) | 2012-03-16 | 2018-07-11 | Albumedix A/S | Albumin variants |
EP3693000B1 (en) | 2012-06-08 | 2022-03-02 | Bioverativ Therapeutics Inc. | Procoagulant compounds |
US10202595B2 (en) | 2012-06-08 | 2019-02-12 | Bioverativ Therapeutics Inc. | Chimeric clotting factors |
CN103525695B (en) * | 2012-07-04 | 2015-05-20 | 长沙中生众捷生物技术有限公司 | Portable kidney function detecting system |
CN104661674A (en) | 2012-07-11 | 2015-05-27 | 阿穆尼克斯运营公司 | Factor VIII complex with XTEN and von willebrand factor protein, and uses thereof |
US10391152B2 (en) | 2012-10-18 | 2019-08-27 | Bioverativ Therapeutics Inc. | Methods of using a fixed dose of a clotting factor |
US20140128326A1 (en) | 2012-11-08 | 2014-05-08 | Novozymes Biopharma Dk A/S | Albumin variants |
DK2956477T4 (en) | 2013-02-15 | 2024-04-15 | Bioverativ Therapeutics Inc | OPTIMIZED FACTOR VIII GENE |
KR20150118123A (en) | 2013-02-16 | 2015-10-21 | 노보자임스 바이오파마 디케이 에이/에스 | Pharmacokinetic animal model |
TWI745671B (en) | 2013-03-15 | 2021-11-11 | 美商百歐維拉提夫治療公司 | Factor ix polypeptide formulations |
SG10201913738YA (en) | 2013-06-28 | 2020-03-30 | Bioverativ Therapeutics Inc | Thrombin cleavable linker with xten and its uses thereof |
WO2015023891A2 (en) | 2013-08-14 | 2015-02-19 | Biogen Idec Ma Inc. | Factor viii-xten fusions and uses thereof |
US10611794B2 (en) | 2013-09-25 | 2020-04-07 | Bioverativ Therapeutics Inc. | On-column viral inactivation methods |
US10584147B2 (en) | 2013-11-08 | 2020-03-10 | Biovertiv Therapeutics Inc. | Procoagulant fusion compound |
DK3091997T5 (en) | 2014-01-10 | 2024-10-14 | Bioverativ Therapeutics Inc | CHIMERIC FACTOR VIII PROTEINS AND USES THEREOF |
WO2016004113A1 (en) | 2014-06-30 | 2016-01-07 | Biogen Ma Inc. | Optimized factor ix gene |
CA2964317C (en) | 2014-10-14 | 2021-10-05 | Halozyme, Inc. | Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same |
MA40835A (en) | 2014-10-23 | 2017-08-29 | Biogen Ma Inc | ANTI-GPIIB / IIIA ANTIBODIES AND THEIR USES |
MA40861A (en) | 2014-10-31 | 2017-09-05 | Biogen Ma Inc | ANTI-GLYCOPROTEIN IIB / IIIA ANTIBODIES |
WO2017024060A1 (en) | 2015-08-03 | 2017-02-09 | Biogen Ma Inc. | Factor ix fusion proteins and methods of making and using same |
CA2989966C (en) | 2015-08-20 | 2024-04-30 | Albumedix A/S | Albumin variants and conjugates |
CA3000742A1 (en) | 2015-10-02 | 2017-04-06 | Silver Creek Pharmaceuticals, Inc. | Bi-specific therapeutic proteins for tissue repair |
CN105254766B (en) * | 2015-10-26 | 2018-10-16 | 中国航天员科研训练中心 | Application of the Mecano growth factor MGF E domain peptides in regulation and control memory related gene and miRNA expression |
US11753461B2 (en) | 2016-02-01 | 2023-09-12 | Bioverativ Therapeutics Inc. | Optimized factor VIII genes |
EA201892448A1 (en) | 2016-04-28 | 2019-06-28 | Эмори Юниверсити | ALKYN-CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND RELATED APPLICATION METHODS |
EP3535585A1 (en) | 2016-11-04 | 2019-09-11 | Aarhus Universitet | Identification and treatment of tumors characterized by an overexpression of the neonatal fc receptor |
JP2019536794A (en) | 2016-12-02 | 2019-12-19 | バイオベラティブ セラピューティクス インコーポレイテッド | Methods for inducing immune tolerance to coagulation factors |
EP3548066A1 (en) | 2016-12-02 | 2019-10-09 | Bioverativ Therapeutics Inc. | Methods of treating hemophilic arthropathy using chimeric clotting factors |
EP3562840A1 (en) | 2016-12-16 | 2019-11-06 | Biogen MA Inc. | Stabilized proteolytically activated growth differentiation factor 11 |
EP3576762A1 (en) | 2017-01-31 | 2019-12-11 | Bioverativ Therapeutics Inc. | Factor ix fusion proteins and methods of making and using same |
MA50141A (en) * | 2017-04-20 | 2020-07-29 | Novo Nordisk As | ALBUMIN FUSION PROTEIN PURIFICATION PROCESSES |
BR112020002394A2 (en) | 2017-08-09 | 2020-07-28 | Bioverativ Therapeutics Inc. | nucleic acid molecules and uses thereof |
TW201946929A (en) | 2018-02-01 | 2019-12-16 | 美商生物化學醫療公司 | Use of lentiviral vectors expressing factor VIII |
NZ769677A (en) | 2018-05-18 | 2024-07-05 | Bioverativ Therapeutics Inc | Methods of treating hemophilia a |
WO2020033863A1 (en) | 2018-08-09 | 2020-02-13 | Bioverativ Therapeutics Inc. | Nucleic acid molecules and uses thereof for non-viral gene therapy |
MX2021006648A (en) | 2018-12-06 | 2021-07-07 | Bioverativ Therapeutics Inc | Use of lentiviral vectors expressing factor ix. |
TW202126284A (en) | 2019-09-30 | 2021-07-16 | 美商百歐維拉提夫治療公司 | Lentiviral vector formulations |
WO2022030580A1 (en) * | 2020-08-06 | 2022-02-10 | 国立大学法人宮崎大学 | Novel long-acting adrenomedullin derivative, method for producing same and pharmaceutical use thereof |
JP2024056667A (en) * | 2022-10-11 | 2024-04-23 | Jcrファーマ株式会社 | Fusion protein of serum albumin and physiologically active protein |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005003296A2 (en) * | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Albumin fusion proteins |
ES2545090T3 (en) * | 2001-12-21 | 2015-09-08 | Human Genome Sciences, Inc. | Albumin and GCSF fusion proteins |
SI1729795T1 (en) * | 2004-02-09 | 2016-04-29 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US20060051859A1 (en) * | 2004-09-09 | 2006-03-09 | Yan Fu | Long acting human interferon analogs |
-
2006
- 2006-07-31 AU AU2006280312A patent/AU2006280312A1/en not_active Abandoned
- 2006-07-31 MX MX2008001865A patent/MX2008001865A/en not_active Application Discontinuation
- 2006-07-31 JP JP2008526056A patent/JP2009504157A/en not_active Withdrawn
- 2006-07-31 KR KR1020087006077A patent/KR20080071119A/en not_active Application Discontinuation
- 2006-07-31 CA CA002618476A patent/CA2618476A1/en not_active Abandoned
- 2006-07-31 EP EP06813242A patent/EP1924596A4/en not_active Withdrawn
- 2006-07-31 WO PCT/US2006/029391 patent/WO2007021494A2/en active Application Filing
- 2006-07-31 BR BRPI0614761-5A patent/BRPI0614761A2/en not_active IP Right Cessation
-
2008
- 2008-02-04 IL IL189246A patent/IL189246A0/en unknown
- 2008-02-11 TN TNP2008000064A patent/TNSN08064A1/en unknown
- 2008-03-07 MA MA30727A patent/MA29836B1/en unknown
- 2008-03-10 NO NO20081233A patent/NO20081233L/en not_active Application Discontinuation
- 2008-03-12 EC EC2008008262A patent/ECSP088262A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007021494A2 (en) | 2007-02-22 |
EP1924596A4 (en) | 2009-07-29 |
KR20080071119A (en) | 2008-08-01 |
EP1924596A2 (en) | 2008-05-28 |
CA2618476A1 (en) | 2007-02-22 |
WO2007021494A3 (en) | 2007-07-26 |
ECSP088262A (en) | 2008-05-30 |
AU2006280312A1 (en) | 2007-02-22 |
JP2009504157A (en) | 2009-02-05 |
MA29836B1 (en) | 2008-10-03 |
BRPI0614761A2 (en) | 2009-05-19 |
TNSN08064A1 (en) | 2009-07-14 |
IL189246A0 (en) | 2008-08-07 |
MX2008001865A (en) | 2008-04-15 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |