NO20076563L - Anti- MCP-1 antistoffer, sammensetninger og anvendelser - Google Patents

Anti- MCP-1 antistoffer, sammensetninger og anvendelser

Info

Publication number
NO20076563L
NO20076563L NO20076563A NO20076563A NO20076563L NO 20076563 L NO20076563 L NO 20076563L NO 20076563 A NO20076563 A NO 20076563A NO 20076563 A NO20076563 A NO 20076563A NO 20076563 L NO20076563 L NO 20076563L
Authority
NO
Norway
Prior art keywords
mcp
compositions
antibodies
methods
antibody
Prior art date
Application number
NO20076563A
Other languages
English (en)
Norwegian (no)
Inventor
Anuk Das
Raymond Sweet
Ping Tsui
Michael Bardroff
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of NO20076563L publication Critical patent/NO20076563L/no

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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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NO20076563A 2005-05-19 2007-12-19 Anti- MCP-1 antistoffer, sammensetninger og anvendelser NO20076563L (no)

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ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
EP2481408A3 (fr) 2007-03-01 2013-01-09 Probiodrug AG Nouvelle utilisation d'inhibiteurs glutaminyle cyclase
EP2865670B1 (fr) 2007-04-18 2017-01-11 Probiodrug AG Dérivés de thio-urée utilisés comme inhibiteurs de la glutaminyl cyclase
CN101827610A (zh) * 2007-06-29 2010-09-08 森托科尔奥索生物科技公司 抗mcp-1抗体、组合物、方法和用途
WO2010020669A1 (fr) * 2008-08-20 2010-02-25 Probiodrug Ag Anticorps dirigés contre une protéine-1 chimiotactique des monocytes a terminal pyroglutamate (mcp-1 n1pe)
EP2475428B1 (fr) 2009-09-11 2015-07-01 Probiodrug AG Dérivés hétérocycliques en tant qu'inhibiteurs de glutaminyle cyclase
ES2586231T3 (es) 2010-03-03 2016-10-13 Probiodrug Ag Inhibidores de glutaminil ciclasa
CN102791704B (zh) 2010-03-10 2015-11-25 前体生物药物股份公司 谷氨酰胺酰环化酶(qc, ec 2.3.2.5)的杂环抑制剂
EP2560953B1 (fr) 2010-04-21 2016-01-06 Probiodrug AG Inhibiteurs de glutaminyl cyclase
US8530670B2 (en) 2011-03-16 2013-09-10 Probiodrug Ag Inhibitors
US20150158942A1 (en) * 2012-05-22 2015-06-11 Shire Human Genetic Therapies, Inc. Anti-ccl2 antibodies for treatment of scleroderma
EP2727944A1 (fr) * 2012-10-30 2014-05-07 Universitätsklinikum Regensburg Déplétion de monocytes positifs de CCR2 pour le traitement des états inflammatoires dans le système gastro-intestinal
US10684290B2 (en) 2014-02-18 2020-06-16 Dignity Health LKB1 related diagnostics and treatments of cancer
ES2764840T3 (es) 2015-01-28 2020-06-04 Univ Bordeaux Uso de plerixafor para tratar y/o prevenir exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej
AU2020259884A1 (en) 2019-04-17 2021-10-07 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination
BR112022012010A2 (pt) * 2019-12-18 2022-08-30 Hoffmann La Roche Anticorpos, ácido nucleico isolado, célula hospedeira, formulação farmacêutica, uso do anticorpo, método de produção de um anticorpo, método de tratamento de um indivíduo que tem câncer e método de tratamento de um indivíduo que tem uma doença inflamatória ou autoimune
CN112358547A (zh) * 2020-09-30 2021-02-12 浙江大学 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用
CN114990073A (zh) * 2022-05-27 2022-09-02 河南农业大学 一种抗猪ccl2蛋白的单克隆抗体及其制备方法和应用

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CN101511869A (zh) 2009-08-19
PA8675801A1 (es) 2006-12-07
CA2609349C (fr) 2012-10-30
AU2010202813B2 (en) 2011-11-03
BRPI0613164A2 (pt) 2010-12-21
JP2008546374A (ja) 2008-12-25
PE20110071A1 (es) 2011-01-31
WO2006125202A3 (fr) 2009-05-07
EA014229B1 (ru) 2010-10-29
AR053470A1 (es) 2007-05-09
NZ563516A (en) 2011-04-29
AU2010202813A1 (en) 2010-07-22
CA2609349A1 (fr) 2006-11-23
EP1888114B1 (fr) 2013-09-18
PE20061444A1 (es) 2007-01-15
WO2006125202A2 (fr) 2006-11-23
ZA200711073B (en) 2009-09-30
EA200702532A1 (ru) 2008-06-30
CN101511869B (zh) 2012-12-12
AU2006247034B2 (en) 2010-12-02
AU2006247034A1 (en) 2006-11-23
JP4975020B2 (ja) 2012-07-11
MX2007014610A (es) 2008-04-14
ES2438193T3 (es) 2014-01-16
TW200716174A (en) 2007-05-01
IL187459A0 (en) 2008-03-20
KR100977823B1 (ko) 2010-08-25
EP1888114A2 (fr) 2008-02-20
EP1888114A4 (fr) 2010-02-24
CR9606A (es) 2010-08-18
KR20080012968A (ko) 2008-02-12

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