NO20075592L - Antistoffer og beslektede molekyler som bindes til PSCA Proteiner - Google Patents

Antistoffer og beslektede molekyler som bindes til PSCA Proteiner

Info

Publication number
NO20075592L
NO20075592L NO20075592A NO20075592A NO20075592L NO 20075592 L NO20075592 L NO 20075592L NO 20075592 A NO20075592 A NO 20075592A NO 20075592 A NO20075592 A NO 20075592A NO 20075592 L NO20075592 L NO 20075592L
Authority
NO
Norway
Prior art keywords
psca
antibodies
bind
variants
fragment
Prior art date
Application number
NO20075592A
Other languages
English (en)
Other versions
NO345322B1 (no
Inventor
Aya Jakobovits
Arthur B Raitano
Pia M Challita-Eid
Xiao-Chi Jia
Robert Kendall Morrison
Jean Gudas
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/131,648 external-priority patent/US7595379B2/en
Priority claimed from PCT/US2005/017412 external-priority patent/WO2005118864A2/en
Priority claimed from PCT/US2006/005693 external-priority patent/WO2006112933A1/en
Application filed by Agensys Inc filed Critical Agensys Inc
Publication of NO20075592L publication Critical patent/NO20075592L/no
Publication of NO345322B1 publication Critical patent/NO345322B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SAMMENDRAG Antistoffer og molekyler avledet derfra som binder til nytt PSCA-protein og varianter derav, er beskrevet hvor PSCA oppviser vevsspesifikk ekspresjon i normalt voksent vev og blir avvikende uttrykt i kreftformen listet opp i Tabell I. Følgelig tilveiebringer PSCA et diagnostisk, prognostisk, profylaktisk og/eller terapeutisk mål for kreft. PSCA-genet eller fragment derav eller dets kodede protein eller varianter derav eller et fragment derav, kan anvendes for å fremkalle en humoral eller cellulær immunrespons; antistoffer eller T-celler reaktive med PSCA kan anvendes ved aktiv eller passiv immunisering.
NO20075592A 2005-04-14 2007-11-05 Antistoffer og beslektede molekyler som bindes til PSCA Proteiner NO345322B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67200005P 2005-04-14 2005-04-14
US11/131,648 US7595379B2 (en) 2003-05-30 2005-05-17 Antibodies and related molecules that bind to PSCA proteins
PCT/US2005/017412 WO2005118864A2 (en) 2004-05-28 2005-05-17 Antibodies and related molecules that bind to psca proteins
PCT/US2006/005693 WO2006112933A1 (en) 2005-04-14 2006-02-15 Antibodies and related molecules that bind to psca proteins

Publications (2)

Publication Number Publication Date
NO20075592L true NO20075592L (no) 2008-01-11
NO345322B1 NO345322B1 (no) 2020-12-07

Family

ID=39226555

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075592A NO345322B1 (no) 2005-04-14 2007-11-05 Antistoffer og beslektede molekyler som bindes til PSCA Proteiner

Country Status (2)

Country Link
CN (1) CN101223191B (no)
NO (1) NO345322B1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3122421A1 (en) * 2018-12-13 2020-06-18 Bellicum Pharmaceuticals, Inc. Psca car-t cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6541212B2 (en) * 1997-03-10 2003-04-01 The Regents Of The University Of California Methods for detecting prostate stem cell antigen protein
EP1514876B1 (en) * 1997-03-10 2013-05-08 The Regents of The University of California Antibody against prostate stem cell antigen (PSCA)
ES2309012T3 (es) * 1999-10-29 2008-12-16 Genentech, Inc. Composiciones del anticuerpo anti-psca y a sus procedimientos contra celulas cancerigenas que expresen psca.
JP2007525196A (ja) * 2003-05-30 2007-09-06 アジェンシス， インコーポレイテッド 前立腺幹細胞抗原（ｐｓｃａ）変異体及びその部分配列

Also Published As

Publication number Publication date
NO345322B1 (no) 2020-12-07
CN101223191A (zh) 2008-07-16
CN101223191B (zh) 2012-09-05

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