NO20073244L - Konjugeringsprodukt - Google Patents

Konjugeringsprodukt

Info

Publication number
NO20073244L
NO20073244L NO20073244A NO20073244A NO20073244L NO 20073244 L NO20073244 L NO 20073244L NO 20073244 A NO20073244 A NO 20073244A NO 20073244 A NO20073244 A NO 20073244A NO 20073244 L NO20073244 L NO 20073244L
Authority
NO
Norway
Prior art keywords
peptide
integrin
selectively inhibits
konjugeringsprodukt
ngr motif
Prior art date
Application number
NO20073244A
Other languages
English (en)
Inventor
Angelo Corti
Flavio Curnis
Original Assignee
Molmed Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molmed Spa filed Critical Molmed Spa
Publication of NO20073244L publication Critical patent/NO20073244L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Abstract

Et peptid som selektivt inhiberer a,P3-integrin som omfatter deamideringsproduktet av et peptid omfattende NGR-motivet. ?Et peptid som selektivt inhiberer a,P3-integrin som omfatter deamideringsproduktet av et peptid omfattende NGR-motivet. Et peptid som selektivt inhiberer ?v?3-integrin som omfatter deamideringsproduktet av et peptid omfattende NGR-motivet.
NO20073244A 2004-12-23 2007-06-22 Konjugeringsprodukt NO20073244L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63815804P 2004-12-23 2004-12-23
PCT/IB2005/004058 WO2006067633A2 (en) 2004-12-23 2005-12-21 Conjugation product

Publications (1)

Publication Number Publication Date
NO20073244L true NO20073244L (no) 2007-09-20

Family

ID=36602131

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073244A NO20073244L (no) 2004-12-23 2007-06-22 Konjugeringsprodukt

Country Status (13)

Country Link
US (2) US7795386B2 (no)
EP (2) EP2364995A1 (no)
JP (1) JP2008525424A (no)
KR (1) KR20070102684A (no)
CN (1) CN101124243A (no)
AU (1) AU2005317684B2 (no)
CA (1) CA2593964A1 (no)
EA (1) EA013967B1 (no)
ES (1) ES2388068T3 (no)
HK (1) HK1106781A1 (no)
IL (2) IL183710A (no)
NO (1) NO20073244L (no)
WO (1) WO2006067633A2 (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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WO2006124726A2 (en) * 2005-05-12 2006-11-23 The General Hospital Corporation Novel biotinylated compositions
GB0624308D0 (en) * 2006-12-05 2007-01-17 Molmed Spa Combination product
GB0708864D0 (en) * 2007-05-08 2007-06-13 Molmed Spa Cytokine Conjugate
EP3783019A1 (en) 2007-10-30 2021-02-24 Philogen S.p.A. An antigen associated with rheumatoid arthritis
RS52460B (en) * 2008-05-13 2013-02-28 Molmed Spa CONJUGATES FOR THE TREATMENT OF MESOTELIOMA
US8636978B2 (en) 2008-06-23 2014-01-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cyclized NGR peptide compounds, compositions, and methods of their use
US8852637B2 (en) 2008-11-14 2014-10-07 Histogen, Inc. Extracellular matrix compositions for the treatment of cancer
IT1394860B1 (it) 2009-07-22 2012-07-20 Kemotech S R L Composti farmaceutici
CN102639555B (zh) * 2009-09-24 2015-11-25 加利福尼亚大学董事会 膀胱癌特异性配体肽
EP3437662B1 (en) * 2011-07-27 2021-02-17 Philogen S.p.A. Il-12 immunoconjugate
GB201204868D0 (en) 2012-03-20 2012-05-02 San Raffaele Centro Fond Peptides
US9526800B2 (en) * 2012-03-28 2016-12-27 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US10024860B2 (en) 2012-03-28 2018-07-17 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US9234007B2 (en) 2012-07-02 2016-01-12 University Of South Florida RGD mimetic γ-AApeptides and methods of use
AU2013308519A1 (en) 2012-08-31 2015-04-09 The General Hospital Corporation Biotin complexes for treatment and diagnosis of Alzheimer's disease
JP6158933B2 (ja) 2012-10-03 2017-07-05 フィロゲン エスピーエー 炎症性腸疾患に関連する抗原
US9645155B2 (en) 2013-08-28 2017-05-09 University Of South Florida Methods of synthesizing γ-aapeptides, γ-aapeptide building blocks, γ-aapeptide libraries, and γ-aapeptide inhibitors of Aβ40 aggregates
FR3010527A1 (fr) * 2013-09-11 2015-03-13 Univ Claude Bernard Lyon Procede de caracterisation de particules
CN103483422B (zh) * 2013-09-22 2015-06-17 中国人民解放军第四军医大学 一种ngr多肽放射性药物及其制备方法与应用
US20170168074A1 (en) 2013-11-25 2017-06-15 Ontochem Gmbh Method for diagnosing G-protein coupled receptor-related diseases
PE20180797A1 (es) 2015-07-16 2018-05-09 Philogen Spa Inmunoconjugados de il22
CN108699164B (zh) * 2016-03-02 2022-06-07 法玛科技顾问股份有限公司 双重标靶药物载体
EP3886824A1 (en) * 2018-11-30 2021-10-06 Fondazione Centro San Raffaele Combined treatment of primary central nervous system lymphoma

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GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5214131A (en) 1988-05-06 1993-05-25 Sumitomo Pharmaceuticals Company, Limited Polyethylene glycol derivatives, modified peptides and production thereof
US5091176A (en) * 1988-11-02 1992-02-25 W. R. Grace & Co.-Conn. Polymer-modified peptide drugs having enhanced biological and pharmacological activities
US5196511A (en) * 1989-12-01 1993-03-23 The Scripps Research Institute Peptides and antibodies that inhibit integrin-ligand binding
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GB0209893D0 (en) 2002-04-30 2002-06-05 Molmed Spa Conjugate

Also Published As

Publication number Publication date
AU2005317684B2 (en) 2012-02-16
IL202570A0 (en) 2011-08-01
JP2008525424A (ja) 2008-07-17
CN101124243A (zh) 2008-02-13
EA013967B1 (ru) 2010-08-30
IL183710A0 (en) 2008-04-13
WO2006067633A2 (en) 2006-06-29
EA200701053A1 (ru) 2008-06-30
HK1106781A1 (en) 2008-03-20
US20110076234A1 (en) 2011-03-31
IL183710A (en) 2012-01-31
US20090068106A1 (en) 2009-03-12
EP1831254B1 (en) 2012-06-06
EP2364995A1 (en) 2011-09-14
CA2593964A1 (en) 2006-06-29
US7795386B2 (en) 2010-09-14
AU2005317684A1 (en) 2006-06-29
WO2006067633A3 (en) 2007-04-05
KR20070102684A (ko) 2007-10-19
ES2388068T3 (es) 2012-10-08
EP1831254A2 (en) 2007-09-12

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application