NO20073015L - Substituted indoles, compositions and processes for their preparation - Google Patents

Substituted indoles, compositions and processes for their preparation

Info

Publication number
NO20073015L
NO20073015L NO20073015A NO20073015A NO20073015L NO 20073015 L NO20073015 L NO 20073015L NO 20073015 A NO20073015 A NO 20073015A NO 20073015 A NO20073015 A NO 20073015A NO 20073015 L NO20073015 L NO 20073015L
Authority
NO
Norway
Prior art keywords
preparation
compositions
processes
substituted indoles
indoles
Prior art date
Application number
NO20073015A
Other languages
Norwegian (no)
Inventor
Baptiste Ronan
Michel Tabart
Fabrice Viviani
Eric Bacque
Frank Halley
Catherine Souaille
Bruno Filoche-Romme
Jean-Philippe Letallec
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0412966A external-priority patent/FR2878849B1/en
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO20073015L publication Critical patent/NO20073015L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00Racemisation; Complete or partial inversion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Foreliggende oppfinnelse angår fremstilling av substituerte indoler, sammensetninger som inneholder dem, en fremgangsmåte for fremstilling derav og deres anvendelse som et medikament, særlig som antikreftmidler.BACKGROUND OF THE INVENTION The present invention relates to the preparation of substituted indoles, to compositions containing them, to a process for their preparation and to their use as a medicament, particularly as anticancer agents.

NO20073015A 2004-12-06 2007-06-13 Substituted indoles, compositions and processes for their preparation NO20073015L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0412966A FR2878849B1 (en) 2004-12-06 2004-12-06 SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING SAME, METHOD OF MANUFACTURE AND USE
US65046505P 2005-02-07 2005-02-07
PCT/FR2005/003003 WO2006061493A1 (en) 2004-12-06 2005-12-02 Substituted indoles, compositions containing them, method for the production thereof and their use

Publications (1)

Publication Number Publication Date
NO20073015L true NO20073015L (en) 2007-08-28

Family

ID=38792212

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073015A NO20073015L (en) 2004-12-06 2007-06-13 Substituted indoles, compositions and processes for their preparation

Country Status (9)

Country Link
JP (1) JP2008532926A (en)
KR (1) KR20070100277A (en)
BR (1) BRPI0515811A (en)
CR (1) CR9115A (en)
EA (1) EA012613B1 (en)
IL (1) IL183438A0 (en)
MA (1) MA29026B1 (en)
MX (1) MX2007006764A (en)
NO (1) NO20073015L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005037499A1 (en) * 2005-08-09 2007-02-15 Merck Patent Gmbh pyrazole
US20220098204A1 (en) * 2019-02-18 2022-03-31 Shenzhen Targetrx, Inc. Substituted fused aromatic ring derivative, composition and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376529B1 (en) * 1995-06-07 2002-04-23 Peng Cho Tang Mono- and bis-indolylquinones and prophylactic and therapeutic uses thereof
JPH11506770A (en) * 1995-06-07 1999-06-15 スーゲン,インコーポレーテッド Methods and compositions for inhibiting adapter protein / tyrosine kinase interactions
US7129225B2 (en) * 2001-10-22 2006-10-31 The Research Foundation Of State University Of New York Protection against and treatment of hearing loss
AU2003243709B2 (en) * 2002-06-24 2007-01-18 Schering Corporation Indole derivatives useful as histamine H3 antagonists
FR2842526B1 (en) * 2002-07-16 2007-07-13 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS COMPRISING A 3-GUANIDINOCARBONYL-1-HETEROARYL-INDOLE DERIVATIVE, PROCESS FOR THE PREPARATION AS MEDICAMENTS
JP2004149429A (en) * 2002-10-29 2004-05-27 Takeda Chem Ind Ltd Indole compound and application thereof

Also Published As

Publication number Publication date
EA200701227A1 (en) 2007-10-26
MX2007006764A (en) 2007-08-15
JP2008532926A (en) 2008-08-21
KR20070100277A (en) 2007-10-10
MA29026B1 (en) 2007-11-01
BRPI0515811A (en) 2008-08-05
IL183438A0 (en) 2007-09-20
CR9115A (en) 2007-10-23
EA012613B1 (en) 2009-10-30

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application