NO20062149L - Bengamide derivatives, methods of preparation and use thereof for the treatment of cancer - Google Patents
Bengamide derivatives, methods of preparation and use thereof for the treatment of cancerInfo
- Publication number
- NO20062149L NO20062149L NO20062149A NO20062149A NO20062149L NO 20062149 L NO20062149 L NO 20062149L NO 20062149 A NO20062149 A NO 20062149A NO 20062149 A NO20062149 A NO 20062149A NO 20062149 L NO20062149 L NO 20062149L
- Authority
- NO
- Norway
- Prior art keywords
- cancer
- preparation
- treatment
- derivatives
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C07D223/10—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Det beskrives bengamidderivater som produseres av mikroorganismen Myxococcus virescens ST2005\611 (DSM 15898) under farmentering. Det beskrives videre anvendelsen av derivatene for behandling av cancer, medikamenter inneholdende derivatene og videre en fremgangsmåte for fremstilling av bengamidene med formel IV. Videre beskrives mikroorganismen Myxococcus virescens ST2005\611 (DSM 15898).Bengamide derivatives produced by the microorganism Myxococcus virescens ST2005 \ 611 (DSM 15898) are described during fermentation. Further described is the use of the derivatives for the treatment of cancer, drugs containing the derivatives and further a process for the preparation of the bengamides of formula IV. Furthermore, the microorganism Myxococcus virescens ST2005 \ 611 (DSM 15898) is described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10349669A DE10349669B3 (en) | 2003-10-24 | 2003-10-24 | Bengamide derivatives, process for their preparation and their use |
PCT/EP2004/011244 WO2005044803A1 (en) | 2003-10-24 | 2004-10-08 | Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20062149L true NO20062149L (en) | 2006-07-11 |
Family
ID=34484998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20062149A NO20062149L (en) | 2003-10-24 | 2006-05-12 | Bengamide derivatives, methods of preparation and use thereof for the treatment of cancer |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP1873146B1 (en) |
JP (1) | JP4769190B2 (en) |
KR (1) | KR20060120044A (en) |
CN (2) | CN100398520C (en) |
AR (1) | AR046553A1 (en) |
AT (2) | ATE420074T1 (en) |
AU (1) | AU2004287561B2 (en) |
BR (1) | BRPI0415529A (en) |
CA (1) | CA2543003A1 (en) |
CL (1) | CL2009000674A1 (en) |
CY (1) | CY1110458T1 (en) |
DE (3) | DE10349669B3 (en) |
DK (1) | DK1680405T3 (en) |
ES (1) | ES2320894T3 (en) |
HK (1) | HK1098131A1 (en) |
HR (1) | HRP20090187T1 (en) |
IL (1) | IL174524A (en) |
MA (1) | MA28213A1 (en) |
ME (1) | MEP33108A (en) |
MX (1) | MXPA06004084A (en) |
NO (1) | NO20062149L (en) |
NZ (1) | NZ546744A (en) |
PL (1) | PL1680405T3 (en) |
PT (1) | PT1680405E (en) |
RS (1) | RS20060263A (en) |
RU (1) | RU2357956C2 (en) |
SI (1) | SI1680405T1 (en) |
UY (1) | UY28574A1 (en) |
WO (1) | WO2005044803A1 (en) |
ZA (1) | ZA200602231B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2878525B1 (en) * | 2004-11-29 | 2007-02-23 | Aventis Pharma Sa | BENGAMIDES HAVING SUBSTITUTED CAPROLACTAM CYCLE, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2878528B1 (en) | 2004-11-29 | 2008-05-16 | Aventis Pharma Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2901556A1 (en) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE DERIVATIVES, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2901555A1 (en) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZOTHIAZEPINE, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2901554B1 (en) | 2006-05-24 | 2011-04-01 | Sanofi Aventis | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZAZEPINE, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO5140099A1 (en) * | 1998-11-17 | 2002-03-22 | Novartis Ag | CERTAIN SUBSTITUTED CAPROLACTAMAS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND ITS USE IN TUMORS TREATMENT |
BR0110641A (en) * | 2000-05-11 | 2003-03-18 | Novartis Ag | Certain substituted caprolactamic carbonates and ethers, pharmaceutical compositions containing them and their use in the treatment of tumors |
JP2004262793A (en) * | 2003-02-28 | 2004-09-24 | Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai | Compound n-9011, its production method and use |
JP2006528611A (en) * | 2003-07-25 | 2006-12-21 | ノバルティス アクチエンゲゼルシャフト | Substituted lactams and their use as anticancer agents |
-
2003
- 2003-10-24 DE DE10349669A patent/DE10349669B3/en not_active Expired - Fee Related
-
2004
- 2004-10-08 AT AT04765884T patent/ATE420074T1/en active
- 2004-10-08 MX MXPA06004084A patent/MXPA06004084A/en active IP Right Grant
- 2004-10-08 PT PT04765884T patent/PT1680405E/en unknown
- 2004-10-08 EP EP07007021A patent/EP1873146B1/en active Active
- 2004-10-08 RU RU2006117769/04A patent/RU2357956C2/en not_active IP Right Cessation
- 2004-10-08 ES ES04765884T patent/ES2320894T3/en active Active
- 2004-10-08 CN CNB2004800306469A patent/CN100398520C/en not_active Expired - Fee Related
- 2004-10-08 CA CA002543003A patent/CA2543003A1/en not_active Abandoned
- 2004-10-08 KR KR1020067007889A patent/KR20060120044A/en not_active Application Discontinuation
- 2004-10-08 EP EP04765884A patent/EP1680405B1/en active Active
- 2004-10-08 SI SI200431054T patent/SI1680405T1/en unknown
- 2004-10-08 CN CNA2008100958532A patent/CN101294173A/en active Pending
- 2004-10-08 JP JP2006535987A patent/JP4769190B2/en not_active Expired - Fee Related
- 2004-10-08 DE DE502004008837T patent/DE502004008837D1/en active Active
- 2004-10-08 DE DE502004011536T patent/DE502004011536D1/en active Active
- 2004-10-08 AT AT07007021T patent/ATE477244T1/en not_active IP Right Cessation
- 2004-10-08 WO PCT/EP2004/011244 patent/WO2005044803A1/en active Application Filing
- 2004-10-08 RS YUP-2006/0263A patent/RS20060263A/en unknown
- 2004-10-08 AU AU2004287561A patent/AU2004287561B2/en not_active Expired - Fee Related
- 2004-10-08 NZ NZ546744A patent/NZ546744A/en unknown
- 2004-10-08 PL PL04765884T patent/PL1680405T3/en unknown
- 2004-10-08 DK DK04765884T patent/DK1680405T3/en active
- 2004-10-08 BR BRPI0415529-7A patent/BRPI0415529A/en not_active IP Right Cessation
- 2004-10-08 ME MEP-331/08A patent/MEP33108A/en unknown
- 2004-10-21 AR ARP040103818A patent/AR046553A1/en not_active Application Discontinuation
- 2004-10-22 UY UY28574A patent/UY28574A1/en unknown
-
2006
- 2006-03-16 ZA ZA200602231A patent/ZA200602231B/en unknown
- 2006-03-23 IL IL174524A patent/IL174524A/en not_active IP Right Cessation
- 2006-04-21 MA MA28955A patent/MA28213A1/en unknown
- 2006-05-12 NO NO20062149A patent/NO20062149L/en not_active Application Discontinuation
-
2007
- 2007-02-15 HK HK07101845A patent/HK1098131A1/en not_active IP Right Cessation
-
2009
- 2009-03-19 CL CL2009000674A patent/CL2009000674A1/en unknown
- 2009-03-23 CY CY20091100336T patent/CY1110458T1/en unknown
- 2009-03-31 HR HR20090187T patent/HRP20090187T1/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |