NO20061292L - Heterosyllic compounds and processes for their preparation and use - Google Patents
Heterosyllic compounds and processes for their preparation and useInfo
- Publication number
- NO20061292L NO20061292L NO20061292A NO20061292A NO20061292L NO 20061292 L NO20061292 L NO 20061292L NO 20061292 A NO20061292 A NO 20061292A NO 20061292 A NO20061292 A NO 20061292A NO 20061292 L NO20061292 L NO 20061292L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- heterosyllic
- processes
- preparation
- compositions
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Forbindelser med formel (I) og fremgangsmåte og/eller sammensetninger som innbefatter forbindelser som er effektive når det gjelder å modulere inflammasjonsresponser, slik som de som er resultat av AGE og glykatert proteinakkumulering er tilveiebrakt. Fremgangsmåte og/eller sammensetninger som innbefatter forbindelser som er effektive når det gjelder å modulere glattmuskelcelleproliferasjon og sykdommer eller tilstander relatert dertil, er også tilveiebrakt.Compounds of formula (I) and process and / or compositions which include compounds that are effective in modulating inflammatory responses, such as those resulting from AGE and glycated protein accumulation, are provided. Methods and / or compositions which include compounds that are effective in modulating smooth muscle cell proliferation and diseases or conditions related thereto are also provided.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN861CH2003 | 2003-10-28 | ||
US61016304P | 2004-09-15 | 2004-09-15 | |
PCT/US2004/035939 WO2005042712A2 (en) | 2003-10-28 | 2004-10-28 | Heterocyclic compounds and methods of making and using thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20061292L true NO20061292L (en) | 2006-07-28 |
Family
ID=34553826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20061292A NO20061292L (en) | 2003-10-28 | 2006-03-21 | Heterosyllic compounds and processes for their preparation and use |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1678157A4 (en) |
JP (2) | JP2007509966A (en) |
KR (1) | KR20070026306A (en) |
AU (1) | AU2004286277A1 (en) |
CA (1) | CA2540460A1 (en) |
IL (1) | IL174249A0 (en) |
NO (1) | NO20061292L (en) |
RU (1) | RU2006112343A (en) |
WO (1) | WO2005042712A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005042712A2 (en) * | 2003-10-28 | 2005-05-12 | Reddy Us Therapeutics, Inc. | Heterocyclic compounds and methods of making and using thereof |
NZ566180A (en) * | 2005-07-29 | 2011-04-29 | Resverlogix Corp | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
PT2118074E (en) | 2007-02-01 | 2014-03-20 | Resverlogix Corp | Compounds for the prevention and treatment of cardiovascular diseases |
US8952021B2 (en) | 2009-01-08 | 2015-02-10 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
AU2010224523B2 (en) | 2009-03-18 | 2014-05-08 | Resverlogix Corp. | Novel anti-inflammatory agents |
MX352614B (en) | 2009-04-22 | 2017-12-01 | Resverlogix Corp | Novel anti-inflammatory agents. |
CZ2009358A3 (en) * | 2009-06-03 | 2010-12-15 | C3 Bio Gmbh | 5,7-Disubstituted 3-isopropylpyrazolo[4,3-d]pyrimidines for use as medicament and pharmaceutical compositions comprising thereof |
TWI495465B (en) * | 2009-09-30 | 2015-08-11 | Shiseido Co Ltd | A heparinase activity inhibitor and a wrinkle improving agent and a pharmaceutical composition containing the same |
PT2773354T (en) | 2011-11-01 | 2019-07-17 | Resverlogix Corp | Oral immediate release formulations for substituted quinazolinones |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
US9073878B2 (en) | 2012-11-21 | 2015-07-07 | Zenith Epigenetics Corp. | Cyclic amines as bromodomain inhibitors |
US9271978B2 (en) | 2012-12-21 | 2016-03-01 | Zenith Epigenetics Corp. | Heterocyclic compounds as bromodomain inhibitors |
JO3789B1 (en) | 2015-03-13 | 2021-01-31 | Resverlogix Corp | Compositions and therapeutic methods for the treatment of complement -associated diseases |
DK3439667T3 (en) | 2016-04-05 | 2024-04-02 | Immune Sensor Llc | CGAS ANTAGONIST COMPOUNDS |
RU2635112C1 (en) * | 2016-12-12 | 2017-11-09 | федеральное государственное автономное образовательное учреждение высшего образования "Южный федеральный университет" | Halides of 1-(4-tert-butylphenyl)-2-{3-[2-(4-fluoro-phenoxy)ethyl]-2-methyl-3h-benzimidazole-1-yl}ethanone with property of rupture cross-linkers of glycated proteins |
CA3123843A1 (en) * | 2018-12-21 | 2020-06-25 | Acurx Pharmaceuticals, Llc | Dna polymerase iiic inhibitors and use thereof |
CN112300141B (en) * | 2020-10-12 | 2023-04-18 | 贵州大学 | Quinazoline-containing myricetin derivative, and preparation method and application thereof |
WO2022255765A1 (en) * | 2021-06-01 | 2022-12-08 | 주식회사 에즈큐리스 | Novel fluorine-substituted flavonoid derivative, and pharmaceutical composition for preventing or treating allergic diseases, comprising same |
TW202334089A (en) | 2021-11-02 | 2023-09-01 | 美商夫雷爾醫療公司 | Pparg inverse agonists and uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1831395A (en) * | 1994-01-14 | 1995-08-01 | Cell Therapeutics, Inc. | Method for treating diseases mediated by cellular proliferation in response to pdgf, egf, fgf and vegf |
TW399051B (en) * | 1996-01-31 | 2000-07-21 | Ssp Co Ltd | A novel benzoazine thiazolidinedione derivative and pharmaceutical composition for reducing blood glucose |
JPH09268189A (en) * | 1996-01-31 | 1997-10-14 | Ss Pharmaceut Co Ltd | Benzoazine derivative or its salt and medicine containing the same |
US5885997A (en) * | 1996-07-01 | 1999-03-23 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
CA2258949C (en) * | 1996-07-01 | 2008-05-06 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
ES2199366T3 (en) * | 1996-12-31 | 2004-02-16 | Dr. Reddy's Laboratories Ltd. | HETEROCICLICAL COMPOUNDS, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED ILLNESSES. |
ES2200248T3 (en) * | 1997-09-19 | 2004-03-01 | Ssp Co., Ltd. | DERIVATIVES OF ACUDI FENILPROPIONICO REPLACED IN ALFA AND MEDICINAL PRODUCT CONTAINING THEM. |
US6028088A (en) * | 1998-10-30 | 2000-02-22 | The University Of Mississippi | Flavonoid derivatives |
US6608038B2 (en) * | 2000-03-15 | 2003-08-19 | Novartis Ag | Methods and compositions for treatment of diabetes and related conditions via gene therapy |
WO2005042712A2 (en) * | 2003-10-28 | 2005-05-12 | Reddy Us Therapeutics, Inc. | Heterocyclic compounds and methods of making and using thereof |
-
2004
- 2004-10-28 WO PCT/US2004/035939 patent/WO2005042712A2/en active Application Filing
- 2004-10-28 EP EP04817481A patent/EP1678157A4/en not_active Withdrawn
- 2004-10-28 AU AU2004286277A patent/AU2004286277A1/en not_active Abandoned
- 2004-10-28 RU RU2006112343/04A patent/RU2006112343A/en not_active Application Discontinuation
- 2004-10-28 KR KR1020067005607A patent/KR20070026306A/en not_active Application Discontinuation
- 2004-10-28 JP JP2006538290A patent/JP2007509966A/en active Pending
- 2004-10-28 CA CA002540460A patent/CA2540460A1/en not_active Abandoned
-
2006
- 2006-03-12 IL IL174249A patent/IL174249A0/en unknown
- 2006-03-21 NO NO20061292A patent/NO20061292L/en not_active Application Discontinuation
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2007
- 2007-10-11 JP JP2007265960A patent/JP2008074858A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2005042712A3 (en) | 2005-07-21 |
CA2540460A1 (en) | 2005-05-12 |
AU2004286277A1 (en) | 2005-05-12 |
JP2007509966A (en) | 2007-04-19 |
EP1678157A4 (en) | 2009-03-18 |
EP1678157A2 (en) | 2006-07-12 |
RU2006112343A (en) | 2007-12-10 |
IL174249A0 (en) | 2006-08-01 |
JP2008074858A (en) | 2008-04-03 |
WO2005042712A2 (en) | 2005-05-12 |
KR20070026306A (en) | 2007-03-08 |
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