NO20061292L - Heterosyllic compounds and processes for their preparation and use - Google Patents

Heterosyllic compounds and processes for their preparation and use

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Publication number
NO20061292L
NO20061292L NO20061292A NO20061292A NO20061292L NO 20061292 L NO20061292 L NO 20061292L NO 20061292 A NO20061292 A NO 20061292A NO 20061292 A NO20061292 A NO 20061292A NO 20061292 L NO20061292 L NO 20061292L
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NO
Norway
Prior art keywords
compounds
heterosyllic
processes
preparation
compositions
Prior art date
Application number
NO20061292A
Other languages
Norwegian (no)
Inventor
Yeleswarapu Koteswar Rao
Manojit Pal
Vedula Manohar Sharma
Akella Venkateswarlu
Ram Pillarisetti
Original Assignee
Reddy Us Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddy Us Therapeutics Inc filed Critical Reddy Us Therapeutics Inc
Publication of NO20061292L publication Critical patent/NO20061292L/en

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P5/40Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
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    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

Forbindelser med formel (I) og fremgangsmåte og/eller sammensetninger som innbefatter forbindelser som er effektive når det gjelder å modulere inflammasjonsresponser, slik som de som er resultat av AGE og glykatert proteinakkumulering er tilveiebrakt. Fremgangsmåte og/eller sammensetninger som innbefatter forbindelser som er effektive når det gjelder å modulere glattmuskelcelleproliferasjon og sykdommer eller tilstander relatert dertil, er også tilveiebrakt.Compounds of formula (I) and process and / or compositions which include compounds that are effective in modulating inflammatory responses, such as those resulting from AGE and glycated protein accumulation, are provided. Methods and / or compositions which include compounds that are effective in modulating smooth muscle cell proliferation and diseases or conditions related thereto are also provided.

NO20061292A 2003-10-28 2006-03-21 Heterosyllic compounds and processes for their preparation and use NO20061292L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN861CH2003 2003-10-28
US61016304P 2004-09-15 2004-09-15
PCT/US2004/035939 WO2005042712A2 (en) 2003-10-28 2004-10-28 Heterocyclic compounds and methods of making and using thereof

Publications (1)

Publication Number Publication Date
NO20061292L true NO20061292L (en) 2006-07-28

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NO20061292A NO20061292L (en) 2003-10-28 2006-03-21 Heterosyllic compounds and processes for their preparation and use

Country Status (9)

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EP (1) EP1678157A4 (en)
JP (2) JP2007509966A (en)
KR (1) KR20070026306A (en)
AU (1) AU2004286277A1 (en)
CA (1) CA2540460A1 (en)
IL (1) IL174249A0 (en)
NO (1) NO20061292L (en)
RU (1) RU2006112343A (en)
WO (1) WO2005042712A2 (en)

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PT2773354T (en) 2011-11-01 2019-07-17 Resverlogix Corp Oral immediate release formulations for substituted quinazolinones
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
US9271978B2 (en) 2012-12-21 2016-03-01 Zenith Epigenetics Corp. Heterocyclic compounds as bromodomain inhibitors
JO3789B1 (en) 2015-03-13 2021-01-31 Resverlogix Corp Compositions and therapeutic methods for the treatment of complement -associated diseases
DK3439667T3 (en) 2016-04-05 2024-04-02 Immune Sensor Llc CGAS ANTAGONIST COMPOUNDS
RU2635112C1 (en) * 2016-12-12 2017-11-09 федеральное государственное автономное образовательное учреждение высшего образования "Южный федеральный университет" Halides of 1-(4-tert-butylphenyl)-2-{3-[2-(4-fluoro-phenoxy)ethyl]-2-methyl-3h-benzimidazole-1-yl}ethanone with property of rupture cross-linkers of glycated proteins
CA3123843A1 (en) * 2018-12-21 2020-06-25 Acurx Pharmaceuticals, Llc Dna polymerase iiic inhibitors and use thereof
CN112300141B (en) * 2020-10-12 2023-04-18 贵州大学 Quinazoline-containing myricetin derivative, and preparation method and application thereof
WO2022255765A1 (en) * 2021-06-01 2022-12-08 주식회사 에즈큐리스 Novel fluorine-substituted flavonoid derivative, and pharmaceutical composition for preventing or treating allergic diseases, comprising same
TW202334089A (en) 2021-11-02 2023-09-01 美商夫雷爾醫療公司 Pparg inverse agonists and uses thereof

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WO2005042712A3 (en) 2005-07-21
CA2540460A1 (en) 2005-05-12
AU2004286277A1 (en) 2005-05-12
JP2007509966A (en) 2007-04-19
EP1678157A4 (en) 2009-03-18
EP1678157A2 (en) 2006-07-12
RU2006112343A (en) 2007-12-10
IL174249A0 (en) 2006-08-01
JP2008074858A (en) 2008-04-03
WO2005042712A2 (en) 2005-05-12
KR20070026306A (en) 2007-03-08

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