NO20054456L - Process for Preparation of Enantiomeric Forms of Cis-Configured 1,3-Cyclohexanediol Derivatives - Google Patents

Process for Preparation of Enantiomeric Forms of Cis-Configured 1,3-Cyclohexanediol Derivatives

Info

Publication number
NO20054456L
NO20054456L NO20054456A NO20054456A NO20054456L NO 20054456 L NO20054456 L NO 20054456L NO 20054456 A NO20054456 A NO 20054456A NO 20054456 A NO20054456 A NO 20054456A NO 20054456 L NO20054456 L NO 20054456L
Authority
NO
Norway
Prior art keywords
cis
preparation
enantiomeric forms
cyclohexanediol derivatives
cyclohexanediol
Prior art date
Application number
NO20054456A
Other languages
Norwegian (no)
Inventor
Wolfgang Holla
Stefanie Keil
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20054456L publication Critical patent/NO20054456L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

Det beskrives en fremgangsmåte for fremstilling av kirale, ikke-racemiske, cis-1,3-disubstituerte sykloheksandioler med formel (I) der gruppene er som definert i beskrivelsen, ved bruk av en enzymatisk oppløsning av racemater.There is disclosed a process for the preparation of chiral, non-racemic, cis-1,3-disubstituted cyclohexanediols of formula (I) wherein the groups are as defined in the specification using an enzymatic solution of racemates.

NO20054456A 2003-02-27 2005-09-26 Process for Preparation of Enantiomeric Forms of Cis-Configured 1,3-Cyclohexanediol Derivatives NO20054456L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10308350A DE10308350B4 (en) 2003-02-27 2003-02-27 Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
PCT/EP2004/001580 WO2004076390A1 (en) 2003-02-27 2004-02-19 Method for producing the enantiomeric forms of cis 1,3-cyclohexanediol derivatives

Publications (1)

Publication Number Publication Date
NO20054456L true NO20054456L (en) 2005-09-26

Family

ID=32863920

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054456A NO20054456L (en) 2003-02-27 2005-09-26 Process for Preparation of Enantiomeric Forms of Cis-Configured 1,3-Cyclohexanediol Derivatives

Country Status (25)

Country Link
EP (1) EP1599433B1 (en)
JP (1) JP2006519001A (en)
KR (1) KR20050107469A (en)
CN (1) CN100572348C (en)
AR (1) AR044501A1 (en)
AT (1) ATE347543T1 (en)
AU (1) AU2004215674B2 (en)
BR (1) BRPI0407844A (en)
CA (1) CA2516623A1 (en)
CO (1) CO5690547A2 (en)
CY (1) CY1106454T1 (en)
DE (2) DE10308350B4 (en)
DK (1) DK1599433T3 (en)
ES (1) ES2278305T3 (en)
HK (1) HK1088889A1 (en)
IL (1) IL170310A (en)
MX (1) MXPA05009053A (en)
NO (1) NO20054456L (en)
NZ (1) NZ542025A (en)
PL (1) PL377812A1 (en)
PT (1) PT1599433E (en)
RU (1) RU2372319C2 (en)
TW (1) TWI331138B (en)
WO (1) WO2004076390A1 (en)
ZA (1) ZA200505760B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038403B4 (en) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Process for preparing the enantiomeric forms of cis-configured 3-hydroxycyclohexanecarboxylic acid derivatives
DE102004040736B4 (en) * 2004-08-23 2007-01-11 Sanofi-Aventis Deutschland Gmbh Process for the preparation of Diarylcycloalkylderivaten
CN101381302B (en) * 2007-09-07 2013-04-03 上海睿智化学研究有限公司 2-bromomethyl-6-methyl benzoyl chloride/bromium and preparation method thereof
EP2679570A3 (en) 2008-05-21 2014-07-02 Taisho Pharmaceutical Co., Ltd. Method of producing bicyclo[3.1.0]hexane derivative
WO2018152286A1 (en) 2017-02-17 2018-08-23 Trevena, Inc. 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
WO2023070605A1 (en) * 2021-10-29 2023-05-04 Trevena, Inc. Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
CN114891838B (en) * 2022-04-29 2023-09-08 株洲壹诺生物技术有限公司 Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenyl) -butyric acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20013834A3 (en) * 1999-04-28 2002-04-17 Aventis Pharma Deutschland Gmbh Derivatives of acids with three aryl radicals as ligands of PPAR receptors and pharmaceutical preparations in which they are comprised
DE10004926A1 (en) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Process for the enzymatic resolution of aminomethyl aryl cyclohexanol derivatives
MXPA04001850A (en) * 2001-08-31 2004-06-15 Aventis Pharma Gmbh Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar activators.

Also Published As

Publication number Publication date
CY1106454T1 (en) 2011-10-12
PL377812A1 (en) 2006-02-20
ES2278305T3 (en) 2007-08-01
JP2006519001A (en) 2006-08-24
HK1088889A1 (en) 2006-11-17
IL170310A (en) 2010-06-16
PT1599433E (en) 2007-02-28
TWI331138B (en) 2010-10-01
NZ542025A (en) 2009-03-31
CN1753855A (en) 2006-03-29
DE10308350A1 (en) 2004-09-16
KR20050107469A (en) 2005-11-11
CN100572348C (en) 2009-12-23
RU2372319C2 (en) 2009-11-10
DE10308350B4 (en) 2006-06-01
ATE347543T1 (en) 2006-12-15
DK1599433T3 (en) 2007-04-16
WO2004076390A1 (en) 2004-09-10
AU2004215674B2 (en) 2010-02-04
BRPI0407844A (en) 2006-02-14
TW200508392A (en) 2005-03-01
CO5690547A2 (en) 2006-10-31
RU2005129993A (en) 2006-01-27
DE502004002234D1 (en) 2007-01-18
EP1599433A1 (en) 2005-11-30
CA2516623A1 (en) 2004-09-10
EP1599433B1 (en) 2006-12-06
MXPA05009053A (en) 2005-10-19
AR044501A1 (en) 2005-09-14
ZA200505760B (en) 2006-05-31
AU2004215674A1 (en) 2004-09-10

Similar Documents

Publication Publication Date Title
NO20054456L (en) Process for Preparation of Enantiomeric Forms of Cis-Configured 1,3-Cyclohexanediol Derivatives
NO20054852L (en) GFAT inhibitors
IS8230A (en) Substitute 2-aminotetraline for use in the treatment of depression
WO2004096757A8 (en) Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
NO20060402L (en) 3-amino choman and 2-aminotetraline derivatives
NO20071140L (en) New piperidine derivatives such as histamine H3 receptor ligands for the treatment of depression
NO20065456L (en) Substituted morpholine compounds for the treatment of central nervous system disorders
NO20054787L (en) Indene derivatives as pharmaceuticals
HRP20050870A2 (en) Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
NO20062256L (en) Hydroxyalkyl-substituted pyrido-7-pyrimidin-7-ones
NO20052182L (en) New connections
ZA200409379B (en) Cationically substituted diphenyl azetidinones, method for their production, medicaments containing said compounds and use thereof
NO20074303L (en) 7- {4- [2- (2,6-dichloro-4-methylphenoxy) ethoxy] phenyl} -3,9-diazabicyclo [3.3.1] non-6-ene-6-karboksylsyresyklopropyl- (2,3- dimethylbenzyl) amide as a renin inhibitor for the treatment of hypertension
NO20056175L (en) Method of preparing enantiomerically pure mirtazapine
EA200600485A1 (en) Method of producing 2-oxo-1-pyrrolidine derivatives
ATE304354T1 (en) POTASSIUM CHANNEL MODULATING IMIDAZOLE DERIVATIVES
NO20062202L (en) Amidomethyl-substituted 2- (4-sulfonylamino) -3-hydroxy-3,4-dihydro-2H-chromene-6-yl derivatives, processes and intermediates for their preparation, and drugs containing these compounds
NO20061045L (en) imidazole
NO20055002L (en) Benzo [1,2,5] thiadiazole
NO20076000L (en) Amino acid derivatives
DE602006009556D1 (en) CHINOLIN DERIVATIVES FOR THE TREATMENT OF MGLUR5 RECEPTOR-MEDIATED ILLNESSES
CA2281918A1 (en) Oxazolidines as 5-ht2a-antagonists
WO2004062562A3 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
WO2004050616A3 (en) Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
WO2003076426A3 (en) Pyridinyloxy derivatives as 5-ht receptor ligands

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application