NO20050745L - New amide compounds with MCH antagonistic effect, and drugs containing such compounds - Google Patents

New amide compounds with MCH antagonistic effect, and drugs containing such compounds

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Publication number
NO20050745L
NO20050745L NO20050745A NO20050745A NO20050745L NO 20050745 L NO20050745 L NO 20050745L NO 20050745 A NO20050745 A NO 20050745A NO 20050745 A NO20050745 A NO 20050745A NO 20050745 L NO20050745 L NO 20050745L
Authority
NO
Norway
Prior art keywords
compounds
antagonistic effect
drugs containing
new amide
amide compounds
Prior art date
Application number
NO20050745A
Other languages
Norwegian (no)
Inventor
Heike-Andrea Wieland
Gerald Juergen Roth
Martin Lenter
Klaus Rudolf
Thorsten Lehmann-Lintz
Stephan Georg Mueller
Ralf Richard Hermann Lotz
Dirk Stenkamp
Philipp Lustenberger
Kirsten Arndt
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO20050745L publication Critical patent/NO20050745L/en

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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Abstract

Foreliggende oppfinnelse angår amidforbindelser med den generelle formel l. Videre angår oppfinnelsen farmasøytiske preparater inneholdende minst ett amid ifølge oppfinnelsen. I betraktning av den MCH-reseptorantagonistiske aktivitet er de farmasøytiske preparater ifølge oppfinnelsen egnet for behandling av metabolske lidelser og/eller spiseforstyrrelser, spesielt fedme, bulimi, anoreksi, hyperfagi og diabetes.The present invention relates to amide compounds of the general formula 1. Furthermore, the invention relates to pharmaceutical compositions containing at least one amide according to the invention. In view of the MCH receptor antagonistic activity, the pharmaceutical compositions of the invention are suitable for the treatment of metabolic disorders and / or eating disorders, especially obesity, bulimia, anorexia, hyperphagia and diabetes.

NO20050745A 2002-10-31 2005-02-11 New amide compounds with MCH antagonistic effect, and drugs containing such compounds NO20050745L (en)

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