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Priority claimed from PCT/EP2003/005153external-prioritypatent/WO2003103714A1/en
Application filed by Pliva Lachema AsfiledCriticalPliva Lachema As
Publication of NO20045398LpublicationCriticalpatent/NO20045398L/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Det er beskrevet et stabihsert farmasøytisk preparat omfattende et farmasøytisk aktivt stoff som er dårlig oppløselig i vann, et oppløseliggjørende middel med et lavt irmhold av både basiske og sure forbindelser og et polart organisk oppløsningsmiddel, spesielt et stabilisert injeksjonskonsentrat, fremgangsmåte for fremstilling av slike stabiliserte farmasøytiske preparater og anvendelsen av et oppløsehggj ørende middel med et lavt irmhold av både basiske og sure forbindelser for å stabilisere farmasøytiske preparater for farmasøytisk aktive stoffer.There is disclosed a stabilized pharmaceutical composition comprising a poorly water-soluble pharmaceutically active substance, a low solubilizer of both basic and acidic compounds, and a polar organic solvent, in particular a stabilized injection concentrate, process for preparing such stabilized pharmaceuticals. compositions and the use of a low-solubility agent of both basic and acidic compounds to stabilize pharmaceutical preparations for pharmaceutically active substances.
NO20045398A2002-06-102004-12-10
Stabilized pharmaceutical preparations based on polyoxyethylated castor oil and process for their preparation
NO20045398L
(en)
Use of melagatran or a pharmaceutically acceptable derivative or prodrug thereof, method of treating inflammation, and, pharmaceutical formulation for use in treating inflammation