NO20040811L - Diarylcycloalkyl derivatives, process for their preparation and their use as PPAR activators. - Google Patents
Diarylcycloalkyl derivatives, process for their preparation and their use as PPAR activators.Info
- Publication number
- NO20040811L NO20040811L NO20040811A NO20040811A NO20040811L NO 20040811 L NO20040811 L NO 20040811L NO 20040811 A NO20040811 A NO 20040811A NO 20040811 A NO20040811 A NO 20040811A NO 20040811 L NO20040811 L NO 20040811L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- preparation
- compounds
- ppar activators
- diarylcycloalkyl derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Det beskrives diaiylcykloalkylderivater samt fysiologisk godtakbare salter derav og fysiologisk funksjonelle derivater derav. Derivatene er forbindelser med formel 1 der restene har nærmere angitte betydninger og videre beskrives fremgangsmåter for fremstilling av forbindelsene.Forbindelsene har lipid- og/eller triglyceirdsenkende egenskaper og egner seg for eksempel for behandling av lipidstoffskifteforstyrrelser, type II diabetes og syndrom X.Diylcycloalkyl derivatives as well as physiologically acceptable salts thereof and physiologically functional derivatives thereof are described. The derivatives are compounds of formula 1 in which the residues have specified meanings and methods for the preparation of the compounds are further described. The compounds have lipid and / or triglyceride lowering properties and are suitable, for example, for the treatment of lipid metabolism disorders, type II diabetes and syndrome X.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2002123273 DE10223273A1 (en) | 2002-05-24 | 2002-05-24 | New (((oxazolylalkyl)-cycloalkyl)-alkyl)-benzoic acid derivatives, are peroxisome proliferator activated receptor agonists or antagonists used e.g. for treating lipid metabolism disorders, type II diabetes, syndrome X and obesity |
PCT/EP2002/009221 WO2003020269A1 (en) | 2001-08-31 | 2002-08-17 | Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar activators |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20040811L true NO20040811L (en) | 2004-05-19 |
NO327067B1 NO327067B1 (en) | 2009-04-14 |
Family
ID=29414152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20040811A NO327067B1 (en) | 2002-05-24 | 2004-02-24 | Diarylcycloalkyl derivatives, use thereof, drug containing one or more such compounds, and method of preparation of drug |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE10223273A1 (en) |
NO (1) | NO327067B1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ555683A (en) | 2004-12-14 | 2010-09-30 | Astrazeneca Ab | Oxadiazole derivatives as dgat inhibitors |
JP2009520786A (en) | 2005-12-22 | 2009-05-28 | アストラゼネカ アクチボラグ | Pyrimido- [4,5-B] -oxazine for use as a DGAT inhibitor |
CA2651663A1 (en) | 2006-05-30 | 2007-12-06 | Astrazeneca Ab | Chemical compounds |
US8084478B2 (en) | 2006-05-30 | 2011-12-27 | Asstrazeneca Ab | Substituted 5- phenylamino- 1, 3, 4-oxadiazol-2-ylcarbonylamino-4-phenoxy-cyclohexane carboxylic acid as inhibitors of acetyl coenzyme A diacylglycerol acyltransferase |
GB0611507D0 (en) * | 2006-06-10 | 2006-07-19 | Astrazeneca Ab | Chemical compounds |
PE20091682A1 (en) | 2007-12-20 | 2009-12-04 | Astrazeneca Ab | CARBAMOYL COMPOUNDS AS INHIBITORS OF DGAT1 190 |
KR20120037939A (en) | 2009-06-19 | 2012-04-20 | 아스트라제네카 아베 | Pyrazine carboxamides as inhibitors of dgat1 |
-
2002
- 2002-05-24 DE DE2002123273 patent/DE10223273A1/en not_active Withdrawn
-
2004
- 2004-02-24 NO NO20040811A patent/NO327067B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO327067B1 (en) | 2009-04-14 |
DE10223273A1 (en) | 2003-12-04 |
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |