NO20016246D0 - Selective iGluR5 receptor antagonist for the treatment of migraine - Google Patents
Selective iGluR5 receptor antagonist for the treatment of migraineInfo
- Publication number
- NO20016246D0 NO20016246D0 NO20016246A NO20016246A NO20016246D0 NO 20016246 D0 NO20016246 D0 NO 20016246D0 NO 20016246 A NO20016246 A NO 20016246A NO 20016246 A NO20016246 A NO 20016246A NO 20016246 D0 NO20016246 D0 NO 20016246D0
- Authority
- NO
- Norway
- Prior art keywords
- migraine
- treatment
- receptor antagonist
- iglur5 receptor
- selective iglur5
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14248599P | 1999-07-06 | 1999-07-06 | |
US15116599P | 1999-08-27 | 1999-08-27 | |
PCT/US2000/016297 WO2001001972A2 (en) | 1999-07-06 | 2000-06-27 | SELECTIVE iGluR5 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20016246D0 true NO20016246D0 (en) | 2001-12-19 |
NO20016246L NO20016246L (en) | 2002-03-04 |
Family
ID=26840135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20016246A NO20016246L (en) | 1999-07-06 | 2001-12-19 | Selective iGluR5 receptor antagonist for the treatment of migraine |
Country Status (28)
Country | Link |
---|---|
US (4) | US6566370B1 (en) |
EP (1) | EP1200073B1 (en) |
JP (1) | JP4619595B2 (en) |
KR (1) | KR20020024300A (en) |
CN (1) | CN1230174C (en) |
AR (1) | AR029373A1 (en) |
AU (1) | AU773304B2 (en) |
BR (1) | BR0012175A (en) |
CA (1) | CA2378613C (en) |
CZ (1) | CZ20014488A3 (en) |
DE (1) | DE60032905T2 (en) |
DK (1) | DK1200073T3 (en) |
DZ (1) | DZ3209A1 (en) |
EA (1) | EA004290B1 (en) |
ES (1) | ES2278619T3 (en) |
HK (1) | HK1047036A1 (en) |
HR (1) | HRP20020013A2 (en) |
HU (1) | HUP0202253A3 (en) |
IL (1) | IL146697A0 (en) |
MX (1) | MXPA01012726A (en) |
MY (1) | MY133503A (en) |
NO (1) | NO20016246L (en) |
NZ (1) | NZ515616A (en) |
PE (1) | PE20010299A1 (en) |
PT (1) | PT1200073E (en) |
SK (1) | SK112002A3 (en) |
TR (1) | TR200200066T2 (en) |
WO (1) | WO2001001972A2 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2574801A (en) | 1999-12-22 | 2001-07-03 | Eli Lilly And Company | Selective iGLUR5 receptor antagonists |
EP1351951A2 (en) * | 2001-01-05 | 2003-10-15 | Eli Lilly And Company | Pyrrolidinylmethyl- and piperidinyl substituted decahydroisoquinolines as excitatory amino acid receptor antagonists |
SK8242003A3 (en) * | 2001-01-05 | 2004-01-08 | Lilly Co Eli | Excitatory amino acid receptor antagonists |
AU2002241565A1 (en) * | 2001-01-05 | 2002-07-16 | Eli Lilly And Company | Excitatory amino acid receptor antagonist and 5-ht1f agonist combination: a method for the treatment of neurological disorders |
WO2002053556A2 (en) * | 2001-01-05 | 2002-07-11 | Eli Lilly And Company | Pyrrolidinylmethyl substituted decahydroisoquinolines as excitatory amino acid receptor antagonists |
US6924294B2 (en) | 2001-01-05 | 2005-08-02 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
US7205313B2 (en) | 2001-01-05 | 2007-04-17 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
ES2306690T3 (en) * | 2001-01-05 | 2008-11-16 | Eli Lilly And Company | ANTAGONISTS OF RECEIVERS OF EXCITATORY AMINO ACIDS. |
GB0128996D0 (en) | 2001-12-04 | 2002-01-23 | Novartis Ag | Organic compounds |
US20040082606A1 (en) * | 2001-12-20 | 2004-04-29 | Khau Vien Van | Excitatory amino acid receptor antagonists |
JP2005529892A (en) | 2002-04-26 | 2005-10-06 | イーライ・リリー・アンド・カンパニー | Decahydroisoquinoline-3-carboxylic acid ester prodrug as an analgesic |
US7960436B2 (en) | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
KR20090079191A (en) | 2006-08-23 | 2009-07-21 | 밸리언트 파마슈티컬즈 인터내셔널 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
US8993593B2 (en) | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
US8722929B2 (en) | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
ATE538084T1 (en) | 2006-11-28 | 2012-01-15 | Valeant Pharmaceuticals Int | BICYCLIC 1,4-RETIGABINE ANALOGAS AS POTASSIUM CHANNEL INHIBITORS |
US8367684B2 (en) | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
US7786146B2 (en) | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
JP2020529975A (en) | 2017-07-31 | 2020-10-15 | ノバルティス アーゲー | Use of Maboglulanto to reduce cocaine use or prevent relapse of cocaine use |
US10591492B2 (en) | 2018-03-05 | 2020-03-17 | Janssen Pharmaceutica Nv | Assays to detect neurodegeneration |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5284957A (en) * | 1992-09-03 | 1994-02-08 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
US5356902A (en) * | 1992-11-06 | 1994-10-18 | Eli Lilly And Company | Decahydroisoquinoline compounds as excitatory amino acid receptor antagonists |
US5446051A (en) | 1994-05-31 | 1995-08-29 | Eli Lilly And Company | Aryl-spaced decahydroisoquinoline-3-carboxylic acids as excitatory amino acid receptor antagonists |
US5767117A (en) | 1994-11-18 | 1998-06-16 | The General Hospital Corporation | Method for treating vascular headaches |
HUP0002030A3 (en) | 1997-04-07 | 2002-01-28 | Lilly Co Eli | Use of glur5 receptorantagonists for the treatment of pain |
ATE240299T1 (en) | 1999-07-06 | 2003-05-15 | Lilly Co Eli | THIS PRODRUGS OF DECAHYDROISCHINOLINE-3- CARBOXYLIC ACID |
-
2000
- 2000-06-27 EP EP00944671A patent/EP1200073B1/en not_active Expired - Lifetime
- 2000-06-27 CN CNB008096880A patent/CN1230174C/en not_active Expired - Fee Related
- 2000-06-27 DZ DZ003209A patent/DZ3209A1/en active
- 2000-06-27 AU AU58732/00A patent/AU773304B2/en not_active Ceased
- 2000-06-27 CA CA002378613A patent/CA2378613C/en not_active Expired - Fee Related
- 2000-06-27 EA EA200200132A patent/EA004290B1/en not_active IP Right Cessation
- 2000-06-27 WO PCT/US2000/016297 patent/WO2001001972A2/en active IP Right Grant
- 2000-06-27 SK SK11-2002A patent/SK112002A3/en not_active Application Discontinuation
- 2000-06-27 KR KR1020027000138A patent/KR20020024300A/en not_active Application Discontinuation
- 2000-06-27 PT PT00944671T patent/PT1200073E/en unknown
- 2000-06-27 CZ CZ20014488A patent/CZ20014488A3/en unknown
- 2000-06-27 JP JP2001507466A patent/JP4619595B2/en not_active Expired - Fee Related
- 2000-06-27 HU HU0202253A patent/HUP0202253A3/en unknown
- 2000-06-27 IL IL14669700A patent/IL146697A0/en unknown
- 2000-06-27 TR TR2002/00066T patent/TR200200066T2/en unknown
- 2000-06-27 DK DK00944671T patent/DK1200073T3/en active
- 2000-06-27 BR BR0012175-4A patent/BR0012175A/en not_active Application Discontinuation
- 2000-06-27 NZ NZ515616A patent/NZ515616A/en unknown
- 2000-06-27 MX MXPA01012726A patent/MXPA01012726A/en active IP Right Grant
- 2000-06-27 DE DE60032905T patent/DE60032905T2/en not_active Expired - Lifetime
- 2000-06-27 US US10/009,655 patent/US6566370B1/en not_active Expired - Fee Related
- 2000-06-27 ES ES00944671T patent/ES2278619T3/en not_active Expired - Lifetime
- 2000-06-29 AR ARP000103296A patent/AR029373A1/en unknown
- 2000-07-04 MY MYPI20003046 patent/MY133503A/en unknown
- 2000-07-04 PE PE2000000672A patent/PE20010299A1/en not_active Application Discontinuation
-
2001
- 2001-12-19 NO NO20016246A patent/NO20016246L/en not_active Application Discontinuation
-
2002
- 2002-01-07 HR HR20020013A patent/HRP20020013A2/en not_active Application Discontinuation
- 2002-09-27 HK HK02107174.1A patent/HK1047036A1/en unknown
-
2003
- 2003-03-06 US US10/383,296 patent/US6759418B2/en not_active Expired - Fee Related
-
2004
- 2004-04-09 US US10/821,698 patent/US6855823B2/en not_active Expired - Fee Related
-
2005
- 2005-01-11 US US11/032,759 patent/US7157582B2/en not_active Expired - Fee Related
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |