NO20013015L - Liposomine inflammatory acid - new transdermal anti-inflammatory drug - Google Patents

Liposomine inflammatory acid - new transdermal anti-inflammatory drug

Info

Publication number
NO20013015L
NO20013015L NO20013015A NO20013015A NO20013015L NO 20013015 L NO20013015 L NO 20013015L NO 20013015 A NO20013015 A NO 20013015A NO 20013015 A NO20013015 A NO 20013015A NO 20013015 L NO20013015 L NO 20013015L
Authority
NO
Norway
Prior art keywords
inflammatory
drug
liposomine
acid
new transdermal
Prior art date
Application number
NO20013015A
Other languages
Norwegian (no)
Other versions
NO20013015D0 (en
Inventor
Konstantinos Demetzos
Helen Kammenou
Michalis Rallis
Georgios Papaioannou
Aristidis Georgopoulos
Georgios Tsamouris
Sofia Hatziantoniou
Georgios Giannisis
Georgios Nounesis
Christina Savva Dimopoulou
Original Assignee
P N Gerolymatos Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by P N Gerolymatos Sa filed Critical P N Gerolymatos Sa
Publication of NO20013015L publication Critical patent/NO20013015L/en
Publication of NO20013015D0 publication Critical patent/NO20013015D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)

Abstract

Innkapsling av medikamentet nifluminsyre i liposomer i den hensikt å danne en ny transdermal ikke-steroid anti-inflammatorisk formulering. Nifluminsyre så vel som dens esterderivater er blitt innkapslet i liposomer med ulike liposomformuleringer for å oppnå økt effektivitet av den aktive forbindelse. Limposomsuspensjonen, med eller uten innkapslet medikament, er blitt formulert som en krem og en stabilitetsstudie av den endelige formulering er blitt utført.Encapsulation of the drug niflumic acid in liposomes for the purpose of forming a new transdermal non-steroidal anti-inflammatory formulation. Niflumic acid as well as its ester derivatives have been encapsulated in liposomes with various liposome formulations to achieve increased efficiency of the active compound. The adhesive suspension, with or without encapsulated drug, has been formulated as a cream and a stability study of the final formulation has been performed.

NO20013015A 1998-12-24 2001-06-18 Liposomine inflammatory acid - new transdermal anti-inflammatory drug NO20013015D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR98100469 1998-12-24
PCT/GR1999/000048 WO2000038681A1 (en) 1998-12-24 1999-12-22 Liposomic niflumic acid - new transdermal anti-inflammatory medicine

Publications (2)

Publication Number Publication Date
NO20013015L true NO20013015L (en) 2001-06-18
NO20013015D0 NO20013015D0 (en) 2001-06-18

Family

ID=10943556

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013015A NO20013015D0 (en) 1998-12-24 2001-06-18 Liposomine inflammatory acid - new transdermal anti-inflammatory drug

Country Status (17)

Country Link
EP (1) EP1140089A1 (en)
JP (1) JP2002533394A (en)
KR (1) KR20010089889A (en)
CN (1) CN1331592A (en)
AU (1) AU1673400A (en)
BR (1) BR9917006A (en)
CA (1) CA2357765A1 (en)
CZ (1) CZ20012240A3 (en)
GR (1) GR1003359B (en)
HU (1) HUP0104853A3 (en)
IL (1) IL143499A0 (en)
IS (1) IS5964A (en)
MX (1) MXPA01006462A (en)
NO (1) NO20013015D0 (en)
PL (1) PL349344A1 (en)
SK (1) SK7962001A3 (en)
WO (1) WO2000038681A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2506746A1 (en) * 2002-11-26 2004-06-10 Gilead Sciences, Inc. Method of drug loading in liposomes by gradient
AU2004233873B2 (en) 2003-04-25 2010-11-18 The Penn State Research Foundation Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
US20050255154A1 (en) 2004-05-11 2005-11-17 Lena Pereswetoff-Morath Method and composition for treating rhinitis
JP4791082B2 (en) * 2005-05-30 2011-10-12 株式会社クラレ Liposomes and topical skin preparations containing the same
JP4931369B2 (en) * 2005-05-31 2012-05-16 ポーラ化成工業株式会社 Liposomes and therapeutic compositions containing the same
SI1888033T1 (en) 2005-06-09 2014-06-30 Meda Ab Method and composition for treating inflammatory disorders
US20120028335A1 (en) 2010-07-28 2012-02-02 Life Technologies Corporation Anti-viral azide-containing compounds
WO2012016048A1 (en) 2010-07-28 2012-02-02 Life Technologies Corporation Anti- viral azide-containing compounds
EP2807252B1 (en) 2012-01-26 2017-05-10 Life Technologies Corporation Methods for increasing the infectivity of viruses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528193A (en) * 1978-12-27 1985-07-09 A. Natterman & Cie. Gmbh Inflammation-preventing pharmaceutical composition of oral administration
EP0225162B1 (en) * 1985-11-27 1992-01-22 Ethicon, Inc. Inhibition of post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug
ES2036593T3 (en) * 1986-06-12 1993-06-01 The Liposome Company, Inc. COMPOSITIONS USING NON-STEROID ANTI-INFLAMMATORY MEDICINES ENCAPSULATED IN LIPOSOMES.
EP0825852B1 (en) * 1995-04-18 2004-07-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposome drug-loading method and composition

Also Published As

Publication number Publication date
IL143499A0 (en) 2002-04-21
CN1331592A (en) 2002-01-16
AU1673400A (en) 2000-07-31
JP2002533394A (en) 2002-10-08
KR20010089889A (en) 2001-10-12
HUP0104853A3 (en) 2003-05-28
MXPA01006462A (en) 2002-06-04
GR1003359B (en) 2000-04-10
CZ20012240A3 (en) 2001-11-14
IS5964A (en) 2001-06-08
HUP0104853A2 (en) 2002-05-29
NO20013015D0 (en) 2001-06-18
CA2357765A1 (en) 2000-07-06
EP1140089A1 (en) 2001-10-10
SK7962001A3 (en) 2002-02-05
PL349344A1 (en) 2002-07-15
BR9917006A (en) 2001-10-30
WO2000038681A1 (en) 2000-07-06

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application