NO20012567D0 - Azepinoindole derivatives, preparation and use thereof - Google Patents
Azepinoindole derivatives, preparation and use thereofInfo
- Publication number
- NO20012567D0 NO20012567D0 NO20012567A NO20012567A NO20012567D0 NO 20012567 D0 NO20012567 D0 NO 20012567D0 NO 20012567 A NO20012567 A NO 20012567A NO 20012567 A NO20012567 A NO 20012567A NO 20012567 D0 NO20012567 D0 NO 20012567D0
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- azepinoindole derivatives
- azepinoindole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19946289A DE19946289A1 (en) | 1999-09-28 | 1999-09-28 | Benzodiazepine derivatives, their production and use |
DE10039610A DE10039610A1 (en) | 2000-08-09 | 2000-08-09 | Azepinoindole derivatives are PARP inhibitors and are useful for the treatment of neurodegenerative diseases, ischemia, tumor, septic shock, inflammation, rheumatic diseases, ARDS and diabetes mellitus |
PCT/EP2000/009024 WO2001023390A2 (en) | 1999-09-28 | 2000-09-15 | Azepinoindole derivatives, the production and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20012567D0 true NO20012567D0 (en) | 2001-05-25 |
NO20012567L NO20012567L (en) | 2001-06-25 |
Family
ID=26006691
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20012567A NO20012567L (en) | 1999-09-28 | 2001-05-25 | Azepinoindole derivatives, preparation and use thereof |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1183259A2 (en) |
JP (1) | JP2003510328A (en) |
KR (1) | KR20010087401A (en) |
CN (1) | CN1374961A (en) |
AU (1) | AU1271201A (en) |
BG (1) | BG105650A (en) |
BR (1) | BR0007174A (en) |
CA (1) | CA2352194A1 (en) |
CZ (1) | CZ20012373A3 (en) |
HK (1) | HK1048999A1 (en) |
HU (1) | HUP0104917A3 (en) |
IL (1) | IL143349A0 (en) |
NO (1) | NO20012567L (en) |
PL (1) | PL347885A1 (en) |
SK (1) | SK8842001A3 (en) |
TR (1) | TR200101499T1 (en) |
WO (1) | WO2001023390A2 (en) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU781711B2 (en) | 1999-01-11 | 2005-06-09 | Agouron Pharmaceuticals, Inc. | Tricyclic inhibitors of poly(ADP-ribose) polymerases |
US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
ES2354249T3 (en) | 2000-12-01 | 2011-03-11 | Eisai Inc. | DERIVATIVES OF AZAFENANTRIDONA AND ITS USE AS PARP INHIBITORS. |
US7026311B2 (en) * | 2002-01-10 | 2006-04-11 | Abbott Gmbh & Co., Kg | Dibenzodiazepine derivatives, their preparation and use |
CA2482806A1 (en) | 2002-04-30 | 2003-11-13 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
EP2036984B1 (en) | 2002-07-26 | 2012-02-22 | BASF Plant Science GmbH | Reversion of the negative selective effect of negative marker proteins as selection procedure |
GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
WO2005028467A1 (en) | 2003-09-15 | 2005-03-31 | Anadys Pharmaceuticals, Inc. | Antibacterial 3,5-diaminopiperidine-substitute aromatic and heteroaromatic compounds |
NZ547984A (en) | 2003-12-01 | 2009-03-31 | Kudos Pharm Ltd | DNA damage repair inhibitors for treatment of cancer |
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
KR20070083484A (en) | 2004-07-14 | 2007-08-24 | 피티씨 테라퓨틱스, 인크. | Methods for treating hepatitis c |
EP1781289A1 (en) | 2004-07-22 | 2007-05-09 | PTC Therapeutics, Inc. | Thienopyridines for treating hepatitis c |
EP2045327B8 (en) | 2005-03-08 | 2012-03-14 | BASF Plant Science GmbH | Expression enhancing intron sequences |
WO2006101937A1 (en) | 2005-03-18 | 2006-09-28 | Janssen Pharmaceutica N.V. | Acylhydrazones as kinase modulators |
GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
UY30639A1 (en) | 2006-10-17 | 2008-05-31 | Kudos Pharm Ltd | SUBSTITUTED DERIVATIVES OF 2H-FTALAZIN-1-ONA, ITS CRYSTAL FORMS, PREPARATION PROCESS AND APPLICATIONS |
CN101809017A (en) | 2007-09-14 | 2010-08-18 | 阿斯利康(瑞典)有限公司 | phthalazinone derivatives |
AR070221A1 (en) | 2008-01-23 | 2010-03-25 | Astrazeneca Ab | DERIVATIVES OF FTALAZINONA POLYMERASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USES OF THE SAME TO PREVENT AND / OR TREAT CANCERIGENE TUMORS, ISCHEMICAL INJURIES AND OTHER ASSOCIATED DISEASES. |
GB0804755D0 (en) * | 2008-03-14 | 2008-04-16 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
PT2346495T (en) | 2008-10-07 | 2016-11-11 | Astrazeneca Uk Ltd | Pharmaceutical formulation 514 |
WO2011058367A2 (en) | 2009-11-13 | 2011-05-19 | Astrazeneca Ab | Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor |
AU2010325549B2 (en) | 2009-11-27 | 2017-04-20 | Basf Plant Science Company Gmbh | Optimized endonucleases and uses thereof |
CA2781835A1 (en) | 2009-11-27 | 2011-06-03 | Basf Plant Science Company Gmbh | Chimeric endonucleases and uses thereof |
CN102686726B (en) | 2009-11-27 | 2015-12-16 | 巴斯夫植物科学有限公司 | Chimeric endonuclease and uses thereof |
EP2575815A4 (en) | 2010-06-04 | 2013-12-25 | Albany Molecular Res Inc | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
ES2879434T3 (en) | 2015-07-23 | 2021-11-22 | Inst Curie | Use of a combination of Dbait molecule and PARP inhibitors for cancer treatment |
GB201519573D0 (en) | 2015-11-05 | 2015-12-23 | King S College London | Combination |
WO2018162439A1 (en) | 2017-03-08 | 2018-09-13 | Onxeo | New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule |
WO2018197461A1 (en) | 2017-04-28 | 2018-11-01 | Akribes Biomedical Gmbh | A parp inhibitor in combination with a glucocorticoid and/or ascorbic acid and/or a protein growth factor for the treatment of impaired wound healing |
JP7264489B2 (en) * | 2017-05-24 | 2023-04-25 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Radiolabeled fluorescent PARP inhibitors for imaging and radiotherapy |
KR20200130856A (en) | 2018-03-13 | 2020-11-20 | 옹쎄오 | Debate molecule for resistance acquired in cancer treatment |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
EP3919495A4 (en) * | 2019-02-02 | 2022-10-19 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Indolo heptamyl oxime analogue as parp inhibitor |
WO2021018298A1 (en) * | 2019-08-01 | 2021-02-04 | 南京明德新药研发有限公司 | Indolo-seven-membered acyloxime compounds as parp inhibitors |
GB201913030D0 (en) | 2019-09-10 | 2019-10-23 | Francis Crick Institute Ltd | Treatment of hr deficient cancer |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
EP4190790A1 (en) * | 2020-07-31 | 2023-06-07 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Indolo heptamyl oxime analog crystal as parp inhibitor and method for preparing same |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999011644A1 (en) * | 1997-09-03 | 1999-03-11 | Guilford Pharmaceuticals Inc. | Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity |
AU781711B2 (en) * | 1999-01-11 | 2005-06-09 | Agouron Pharmaceuticals, Inc. | Tricyclic inhibitors of poly(ADP-ribose) polymerases |
ECSP003637A (en) * | 1999-08-31 | 2002-03-25 | Agouron Pharma | TRICYCLE POLY INHIBITORS (ADP-RIBOSA) POLYMERASES |
-
2000
- 2000-09-15 AU AU12712/01A patent/AU1271201A/en not_active Abandoned
- 2000-09-15 SK SK884-2001A patent/SK8842001A3/en unknown
- 2000-09-15 CA CA002352194A patent/CA2352194A1/en not_active Abandoned
- 2000-09-15 PL PL00347885A patent/PL347885A1/en not_active Application Discontinuation
- 2000-09-15 CN CN00802408A patent/CN1374961A/en active Pending
- 2000-09-15 EP EP00974379A patent/EP1183259A2/en not_active Withdrawn
- 2000-09-15 TR TR2001/01499T patent/TR200101499T1/en unknown
- 2000-09-15 CZ CZ20012373A patent/CZ20012373A3/en unknown
- 2000-09-15 BR BR0007174-9A patent/BR0007174A/en not_active IP Right Cessation
- 2000-09-15 IL IL14334900A patent/IL143349A0/en unknown
- 2000-09-15 WO PCT/EP2000/009024 patent/WO2001023390A2/en not_active Application Discontinuation
- 2000-09-15 HU HU0104917A patent/HUP0104917A3/en unknown
- 2000-09-15 JP JP2001526542A patent/JP2003510328A/en active Pending
- 2000-09-15 KR KR1020017006614A patent/KR20010087401A/en not_active Application Discontinuation
-
2001
- 2001-05-25 NO NO20012567A patent/NO20012567L/en not_active Application Discontinuation
- 2001-06-26 BG BG105650A patent/BG105650A/en unknown
-
2003
- 2003-02-18 HK HK03101179.8A patent/HK1048999A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001023390A3 (en) | 2001-12-27 |
CZ20012373A3 (en) | 2002-05-15 |
HUP0104917A3 (en) | 2002-12-28 |
HK1048999A1 (en) | 2003-04-25 |
SK8842001A3 (en) | 2002-01-07 |
EP1183259A2 (en) | 2002-03-06 |
IL143349A0 (en) | 2002-04-21 |
PL347885A1 (en) | 2002-04-22 |
BG105650A (en) | 2002-02-28 |
WO2001023390A2 (en) | 2001-04-05 |
CN1374961A (en) | 2002-10-16 |
AU1271201A (en) | 2001-04-30 |
JP2003510328A (en) | 2003-03-18 |
KR20010087401A (en) | 2001-09-15 |
NO20012567L (en) | 2001-06-25 |
TR200101499T1 (en) | 2002-09-23 |
HUP0104917A2 (en) | 2002-04-29 |
BR0007174A (en) | 2001-09-04 |
CA2352194A1 (en) | 2001-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |