NO20005932L - New compounds derived from <alfa> -D-xylose, and their preparation and therapeutic use - Google Patents

New compounds derived from <alfa> -D-xylose, and their preparation and therapeutic use

Info

Publication number
NO20005932L
NO20005932L NO20005932A NO20005932A NO20005932L NO 20005932 L NO20005932 L NO 20005932L NO 20005932 A NO20005932 A NO 20005932A NO 20005932 A NO20005932 A NO 20005932A NO 20005932 L NO20005932 L NO 20005932L
Authority
NO
Norway
Prior art keywords
preparation
xylose
alfa
therapeutic use
new compounds
Prior art date
Application number
NO20005932A
Other languages
Norwegian (no)
Other versions
NO20005932D0 (en
Inventor
Veronique Barberousse
Christiane Legendre
Soth Samreth
Alan Dunlap Edgar
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Publication of NO20005932D0 publication Critical patent/NO20005932D0/en
Publication of NO20005932L publication Critical patent/NO20005932L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

a-D-xyloseforbindelse med formel (I): der X og Y uavhengig av hverandre betyr et oksygen- eller et svovelatom, RI betyr en CN-, CF3- eller S02CH3-gruppe og R betyr et hydrogenatom eller en alifatisk acylgruppe med 2 til 5 karbonatomer. Forbindelsenes fremstilling beskrives. Forbindelsene finner særlig anvendelse for fremstilling av medikamenter til bruk vis a vis aterosklerose.aD-xylose compound of formula (I): wherein X and Y independently represent an oxygen or sulfur atom, R 1 represents a CN, CF 3 or SO 2 CH 3 group and R represents a hydrogen atom or an aliphatic acyl group having 2 to 5 carbon atoms . The preparation of the compounds is described. The compounds find particular application for the manufacture of medicaments for use in atherosclerosis.

NO20005932A 1998-06-24 2000-11-24 New compounds derived from <alfa> -D-xylose, and their preparation and therapeutic use NO20005932L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9056698P 1998-06-24 1998-06-24
PCT/FR1999/001387 WO1999067261A1 (en) 1998-06-24 1999-06-11 NOVEL COMPOUNDS DERIVED FROM α-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE

Publications (2)

Publication Number Publication Date
NO20005932D0 NO20005932D0 (en) 2000-11-24
NO20005932L true NO20005932L (en) 2001-01-30

Family

ID=22223347

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005932A NO20005932L (en) 1998-06-24 2000-11-24 New compounds derived from <alfa> -D-xylose, and their preparation and therapeutic use

Country Status (20)

Country Link
EP (1) EP1090017B1 (en)
JP (1) JP2002518508A (en)
KR (1) KR20010053038A (en)
CN (1) CN1305486A (en)
AR (1) AR019701A1 (en)
AT (1) ATE226956T1 (en)
AU (1) AU746680B2 (en)
BR (1) BR9911585A (en)
CA (1) CA2335799A1 (en)
DE (1) DE69903727D1 (en)
EE (1) EE200000752A (en)
HK (1) HK1039128A1 (en)
HU (1) HUP0102772A3 (en)
ID (1) ID26806A (en)
IL (1) IL140417A0 (en)
NO (1) NO20005932L (en)
PL (1) PL345068A1 (en)
SK (1) SK20122000A3 (en)
TR (1) TR200003797T2 (en)
WO (1) WO1999067261A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2802929B1 (en) * 1999-12-23 2003-06-06 Fournier Ind & Sante BENZOPHENONE ALPHA-D-GLYCOPYRANOSIDES, PREPARATION AND USE IN THERAPEUTICS
FR2826367B1 (en) * 2001-06-21 2004-01-30 Fournier Lab Sa NOVEL 4- (4-CYANOBENZOYL) PHENYL] GLYCOPYRANOSIDE DERIVATIVES, USE AS MEDICAMENT, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
FR2826368B1 (en) * 2001-06-21 2004-01-30 Fournier Lab Sa NOVEL [4- (4-CYANOBENZOYL) PHENYL] GLYCOFURANOSIDE DERIVATIVES, USE AS MEDICAMENT, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US7800101B2 (en) 2006-01-05 2010-09-21 Samsung Electronics Co., Ltd. Thin film transistor having openings formed therein
FR2903698B1 (en) * 2006-07-13 2009-01-30 Fournier S A Sa Lab NOVEL 5-THIOXYLOPYRANOSE DERIVATIVES.
CN105367614B (en) * 2015-11-24 2019-02-22 中国人民解放军第二军医大学 Preparation method containing glucose derivative of fatty acid and its application in field of medicaments
CN109836462B (en) * 2017-11-28 2021-12-28 重庆圣华曦药业股份有限公司 Preparation method of triacetyl deoxyribose alpha isomer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492830A1 (en) * 1980-10-29 1982-04-30 Sori Soc Rech Ind NOVEL COMPOUNDS BELONGING TO THE BENZOYL- AND A-HYDROXYBENZYL-PHENYL-OSIDES FAMILY, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC APPLICATION
FR2614893B1 (en) * 1987-05-04 1989-12-22 Fournier Innovation Synergie NOVEL B-D-PHENYL-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS

Also Published As

Publication number Publication date
HK1039128A1 (en) 2002-04-12
ID26806A (en) 2001-02-08
EP1090017A1 (en) 2001-04-11
AR019701A1 (en) 2002-03-13
TR200003797T2 (en) 2001-06-21
NO20005932D0 (en) 2000-11-24
CA2335799A1 (en) 1999-12-29
HUP0102772A2 (en) 2001-12-28
BR9911585A (en) 2001-03-20
PL345068A1 (en) 2001-12-03
AU4049099A (en) 2000-01-10
SK20122000A3 (en) 2001-07-10
KR20010053038A (en) 2001-06-25
AU746680B2 (en) 2002-05-02
EE200000752A (en) 2002-04-15
HUP0102772A3 (en) 2003-11-28
WO1999067261A1 (en) 1999-12-29
ATE226956T1 (en) 2002-11-15
JP2002518508A (en) 2002-06-25
EP1090017B1 (en) 2002-10-30
IL140417A0 (en) 2002-02-10
DE69903727D1 (en) 2002-12-05
CN1305486A (en) 2001-07-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application